Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 3 de 3
Korean J Parasitol ; 59(4): 399-402, 2021 Aug.
Article in English | MEDLINE | ID: covidwho-1381388


The COVID-19 pandemic continues to be a major health problem worldwide. Timely diagnosis of co-infections mimicking COVID-19, such as malaria, might be challenging particularly in non-endemic areas. We report the first case of COVID-19 and Plasmodium ovale malaria co-infection from our region aiming to highligt the importance of travel history and prophylaxis in malaria management in the context of pandemic. The galloping sound can sometimes be a harbinger of zebra besides the horse.

COVID-19/virology , Coinfection/parasitology , Coinfection/virology , Malaria/parasitology , Plasmodium ovale/physiology , Adult , Humans , Male , Plasmodium ovale/genetics , SARS-CoV-2/genetics , SARS-CoV-2/physiology
Am J Trop Med Hyg ; 103(2): 572-577, 2020 08.
Article in English | MEDLINE | ID: covidwho-459519


The COVID-19 pandemic, caused by SARS-CoV-2, have surpassed 5 million cases globally. Current models suggest that low- and middle-income countries (LMICs) will have a similar incidence but substantially lower mortality rate than high-income countries. However, malaria and neglected tropical diseases (NTDs) are prevalent in LMICs, and coinfections are likely. Both malaria and parasitic NTDs can alter immunologic responses to other infectious agents. Malaria can induce a cytokine storm and pro-coagulant state similar to that seen in severe COVID-19. Consequently, coinfections with malaria parasites and SARS-CoV-2 could result in substantially worse outcomes than mono-infections with either pathogen, and could shift the age pattern of severe COVID-19 to younger age-groups. Enhancing surveillance platforms could provide signals that indicate whether malaria, NTDs, and COVID-19 are syndemics (synergistic epidemics). Based on the prevalence of malaria and NTDs in specific localities, efforts to characterize COVID-19 in LMICs could be expanded by adding testing for malaria and NTDs. Such additional testing would allow the determination of the rates of coinfection and comparison of severity of outcomes by infection status, greatly improving the understanding of the epidemiology of COVID-19 in LMICs and potentially helping to mitigate its impact.

Coronavirus Infections/epidemiology , Malaria/epidemiology , Parasitic Diseases/epidemiology , Pneumonia, Viral/epidemiology , Syndemic , Betacoronavirus , COVID-19 , Coinfection/epidemiology , Coinfection/parasitology , Coinfection/virology , Developing Countries , Humans , Neglected Diseases/epidemiology , Pandemics , SARS-CoV-2 , Tropical Medicine