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Drug Discov Today ; 26(8): 1929-1935, 2021 08.
Article in English | MEDLINE | ID: covidwho-1163655

ABSTRACT

The concept of going 'green' and 'cold' has led to utilizing renewable resources for the synthesis of microbial biosurfactants that are both patient and eco-friendly. In this review, we shed light on the potential and regulatory aspects of biosurfactants in pharmaceutical applications and how they can significantly contribute to novel concepts for the Coronavirus 2019 (COVID-19) vaccine and future treatment. We emphasize that more specific guidelines should be formulated to regulate the approval of biosurfactants for human use. It is also crucial to implement a risk-based approach from the early research and development (R&D) phase in addition to establishing more robust standardized techniques and assays to evaluate the characteristics of biosurfactants.


Subject(s)
Antiviral Agents/pharmacology , COVID-19 Drug Treatment , COVID-19 Vaccines/pharmacology , COVID-19 , Drug Discovery , SARS-CoV-2 , Surface-Active Agents/pharmacology , COVID-19/prevention & control , Drug Discovery/methods , Drug Discovery/trends , Drug and Narcotic Control/organization & administration , Ecological and Environmental Phenomena , Humans , Nanostructures , Pharmaceutical Preparations/classification , SARS-CoV-2/drug effects , SARS-CoV-2/physiology
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