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Sci Adv ; 7(20)2021 05.
Article in English | MEDLINE | ID: covidwho-1226704


Soft, skin-integrated electronic sensors can provide continuous measurements of diverse physiological parameters, with broad relevance to the future of human health care. Motion artifacts can, however, corrupt the recorded signals, particularly those associated with mechanical signatures of cardiopulmonary processes. Design strategies introduced here address this limitation through differential operation of a matched, time-synchronized pair of high-bandwidth accelerometers located on parts of the anatomy that exhibit strong spatial gradients in motion characteristics. When mounted at a location that spans the suprasternal notch and the sternal manubrium, these dual-sensing devices allow measurements of heart rate and sounds, respiratory activities, body temperature, body orientation, and activity level, along with swallowing, coughing, talking, and related processes, without sensitivity to ambient conditions during routine daily activities, vigorous exercises, intense manual labor, and even swimming. Deployments on patients with COVID-19 allow clinical-grade ambulatory monitoring of the key symptoms of the disease even during rehabilitation protocols.

Accelerometry/instrumentation , Accelerometry/methods , Electrocardiography, Ambulatory/instrumentation , Electrocardiography, Ambulatory/methods , Wearable Electronic Devices , Body Temperature , COVID-19 , Exercise/physiology , Heart Rate , Humans , Monitoring, Physiologic/instrumentation , Monitoring, Physiologic/methods , SARS-CoV-2
J Electrocardiol ; 64: 72-75, 2021.
Article in English | MEDLINE | ID: covidwho-933250


In response to the COVID-19 pandemic, a protocol was designed for mail-out devices and educational materials created to teach patients how to install a device for 2 weeks of continuous ambulatory ECG monitoring. We compared data collection from two sequential patient populations; one who received standard device application in the same clinic in the months before the pandemic response, and another, who received their device by mail for self-installation. Patients received a single phone call when the device was mailed and were able to contact the manufacturer as needed for support. A total of 47 devices were assessed from each group. Each group was similar in age (70 vs 65 years), and clinical indication for monitoring. Noise signal magnitude (22.34 vs 26.28%), symptom based manual activation (10 vs 8 events) and APB/recorded hour burden measurements (37.05 vs 23.36%) were similar in both groups (all comparisons were statistically non-significant). Both groups had a similar mean of hours recorded (240.37 vs. 245.05 h). Zero patient kits were lost, and all reports were delivered. Overall, it was found that a mail-delivered home-based recording platform can be reliably used to acquire clinical data with similar data quality and patient compliance as a conventional in-clinic model for long term ambulatory ECG monitoring.

Electrocardiography, Ambulatory , Patient Education as Topic/methods , Aged , COVID-19 , Electrocardiography, Ambulatory/instrumentation , Electrocardiography, Ambulatory/methods , Female , Home Care Services , Humans , Male , Middle Aged , Self-Management