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MMWR Morb Mortal Wkly Rep ; 71(8): 319-324, 2022 Feb 25.
Article in English | MEDLINE | ID: covidwho-1702097


In 2021, a national emergency* for children's mental health was declared by several pediatric health organizations, and the U.S. Surgeon General released an advisory† on mental health among youths. These actions resulted from ongoing concerns about children's mental health in the United States, which was exacerbated by the COVID-19 pandemic (1,2). During March-October 2020, among all emergency department (ED) visits, the proportion of mental health-related visits increased by 24% among U.S. children aged 5-11 years and 31% among adolescents aged 12-17 years, compared with 2019 (2). CDC examined changes in U.S. pediatric ED visits for overall mental health conditions (MHCs) and ED visits associated with specific MHCs (depression; anxiety; disruptive behavioral and impulse-control disorders; attention-deficit/hyperactivity disorder; trauma and stressor-related disorders; bipolar disorders; eating disorders; tic disorders; and obsessive-compulsive disorders [OCD]) during 2019 through January 2022 among children and adolescents aged 0-17 years, overall and by sex and age. After declines in weekly visits associated with MHCs among those aged 0-17 years during 2020, weekly numbers of ED visits for MHCs overall and for specific MHCs varied by age and sex during 2021 and January 2022, when compared with corresponding weeks in 2019. Among adolescent females aged 12-17 years, weekly visits increased for two of nine MHCs during 2020 (eating disorders and tic disorders), for four of nine MHCs during 2021 (depression, eating disorders, tic disorders, and OCD), and for five of nine MHCs during January 2022 (anxiety, trauma and stressor-related disorders, eating disorders, tic disorders, and OCD), and overall MHC visits during January 2022, compared with 2019. Early identification and expanded evidence-based prevention and intervention strategies are critical to improving children's and adolescents' mental health (1-3), especially among adolescent females, who might have increased need.

Emergency Service, Hospital/statistics & numerical data , Emergency Treatment/trends , Facilities and Services Utilization/trends , Mental Disorders/psychology , Mental Health , Adolescent , Age Distribution , COVID-19/epidemiology , Child , Child, Preschool , Female , Humans , Infant , Male , Mental Disorders/classification , SARS-CoV-2 , Sentinel Surveillance , Sex Distribution , United States/epidemiology
Int J Mol Sci ; 22(16)2021 Aug 05.
Article in English | MEDLINE | ID: covidwho-1341694


The current coronavirus disease-19 (COVID-19) pandemic has strongly revived the pressing need to incorporate new therapeutic alternatives to deal with medical situations that result in a dramatic breakdown in the body's normal homeostasis [...].

Acute Disease/therapy , COVID-19/therapy , Emergency Treatment/methods , Mesenchymal Stem Cell Transplantation/methods , Regenerative Medicine/methods , Acute Disease/mortality , COVID-19/mortality , Clinical Trials as Topic , Emergency Service, Hospital , Emergency Treatment/trends , Humans , Mesenchymal Stem Cell Transplantation/trends , Regenerative Medicine/trends , Survival Rate , Treatment Outcome
Urology ; 147: 43-49, 2021 01.
Article in English | MEDLINE | ID: covidwho-884792


OBJECTIVE: To quantify and characterize the burden of urological patients admitted to emergency department (ED) in Lombardy during Italian COVID-19 outbreak, comparing it to a reference population from 2019. METHODS: We retrospectively analysed all consecutive admissions to ED from 1 January to 9 April in both 2019 and 2020. According to the ED discharge ICD-9-CM code, patients were grouped in urological and respiratory patients. We evaluated the type of access (self-presented/ambulance), discharge priority code, ED discharge (hospitalization, home), need for urological consultation or urgent surgery. RESULTS: The number of urological diagnoses in ED was inversely associated to COVID-19 diagnoses (95% confidence interval -0.41/-0.19; Beta = -0.8; P < .0001). The average access per day was significantly lower after 10 March 2020 (1.5 ± 1.1 vs 6.5 ± 2.6; P < .0001), compared to reference period. From 11 March 2020, the inappropriate admissions to ED were reduced (10/45 vs 96/195; P = .001). Consequently, the patients admitted were generally more demanding, requiring a higher rate of urgent surgeries (4/45 vs 4/195; P = .02). This reflected in an increase of the hospitalization rate from 12.7% to 17.8% (Beta = 0.88; P < .0001) during 2020. CONCLUSION: Urological admissions to ED during lockdown differed from the same period of 2019 both qualitatively and quantitatively. The spectrum of patients seems to be relatively more critical, often requiring an urgent management. These patients may represent a challenge due to the difficult circumstances caused by the pandemic.

COVID-19/prevention & control , Communicable Disease Control/standards , Emergency Treatment/trends , Pandemics/prevention & control , Urologic Diseases/therapy , Academic Medical Centers/standards , Academic Medical Centers/statistics & numerical data , Academic Medical Centers/trends , Adult , Aged , Aged, 80 and over , COVID-19/epidemiology , COVID-19/transmission , Communicable Disease Control/trends , Emergency Service, Hospital/statistics & numerical data , Emergency Service, Hospital/trends , Emergency Treatment/statistics & numerical data , Female , Humans , Italy/epidemiology , Male , Middle Aged , Patient Admission/standards , Patient Admission/statistics & numerical data , Patient Admission/trends , Patient Discharge/standards , Patient Discharge/statistics & numerical data , Patient Discharge/trends , Referral and Consultation/statistics & numerical data , Referral and Consultation/trends , Retrospective Studies , SARS-CoV-2/pathogenicity , Tertiary Care Centers/standards , Tertiary Care Centers/statistics & numerical data , Tertiary Care Centers/trends , Urologic Diseases/diagnosis , Urologic Surgical Procedures/statistics & numerical data , Urologic Surgical Procedures/trends