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Eur J Endocrinol ; 185(2): C1-C7, 2021 Jul 05.
Article in English | MEDLINE | ID: covidwho-1298092


Changes that COVID-19 induced in endocrine daily practice as well as the role of endocrine and metabolic comorbidities in COVID-19 outcomes were among the striking features of this last year. The aim of this statement is to illustrate the major characteristics of the response of European endocrinologists to the pandemic including the disclosure of the endocrine phenotype of COVID-19 with diabetes, obesity and hypovitaminosis D playing a key role in this clinical setting with its huge implication for the prevention and management of the disease. The role of the European Society of Endocrinology (ESE) as a reference point of the endocrine community during the pandemic will also be highlighted, including the refocusing of its educational and advocacy activities.

COVID-19/epidemiology , COVID-19/therapy , Endocrinologists/organization & administration , Endocrinology/organization & administration , COVID-19/complications , COVID-19/prevention & control , Community Networks/organization & administration , Community Networks/trends , Delivery of Health Care/history , Delivery of Health Care/organization & administration , Delivery of Health Care/trends , Endocrine System Diseases/diagnosis , Endocrine System Diseases/epidemiology , Endocrine System Diseases/etiology , Endocrine System Diseases/therapy , Endocrinologists/history , Endocrinologists/trends , Endocrinology/history , Endocrinology/trends , Europe/epidemiology , History, 21st Century , Humans , Pandemics , Phenotype , Physician's Role , Practice Patterns, Physicians'/history , Practice Patterns, Physicians'/organization & administration , Practice Patterns, Physicians'/trends , Societies, Medical/history , Societies, Medical/organization & administration , Societies, Medical/trends , Telemedicine/history , Telemedicine/organization & administration , Telemedicine/trends
Minerva Endocrinol ; 45(4): 345-353, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-792806


INTRODUCTION: In the next future, dermatologists, endocrinologist and physicians may cope with the impact of extent SARS-CoV-2 (COVID-19) infection over chronic inflammatory skin diseases and their treatment. COVID-19 pandemic obliged many countries to impose social restrictions, resulting in the need to adapt daily lifestyle habits and working activities. These changes have drastically reduced physical activity and social interactions, with the possible increase of anxiety, eating disorders and weight gain. EVIDENCE ACQUISITION: We searched for relevant studies (trials, real-life studies and case reports, meta-analysis, pooled data analysis, reviews) on endocrine disorders and inflammatory skin diseases. The database used was PubMed. The studies included were those published in the English language between January 1, 2018 and May 5, 2020. EVIDENCE SYNTHESIS: Several studies have been previously showed the association of overweight and obesity, with the metabolic syndrome and insulin-resistance. It has been demonstrated how these conditions correlate with the worsening of such chronic inflammatory skin diseases, such as psoriasis, hidradenitis suppurativa and acne. Many evidences suggest an important role of adipose tissue in the production of pro-inflammatory cytokines (Leptin, adiponectin, TNFα, IL-6, MCP-1, PAI-1), involved in the pathogenesis and the exacerbations of these skin diseases. In addition, we should expect an increasing incidence rate of hypovitaminosis D in the next future due to reduced sun exposure caused by isolation at home and missed holidays. Scientific evidences already show the important immunomodulating role of vitamin D in inflammatory skin diseases. CONCLUSIONS: Our study pays attention on medium-long term effects of COVID-19 outbreak on inflammatory skin disorders, due to the lifestyle changes. In such context this review considers how a multidisciplinary approach, involving dermatologists, nutritionists and endocrinologists, may lead to a better management of dermatologic patients.

COVID-19/complications , Dermatitis/etiology , Endocrine System Diseases/etiology , COVID-19/epidemiology , Disease Outbreaks , Humans