Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 3 de 3
BMC Infect Dis ; 21(1): 833, 2021 Aug 19.
Article in English | MEDLINE | ID: covidwho-1365329


BACKGROUND: Bordetella avium, an aerobic bacterium that rarely causes infection in humans, is a species of Bordetella that generally inhabits the respiratory tracts of turkeys and other birds. It causes a highly contagious bordetellosis. Few reports describe B. avium as a causative agent of eye-related infections. CASE PRESENTATION: We report a case of acute infectious endophthalmitis associated with infection by B. avium after open trauma. After emergency vitrectomy and subsequent broad-spectrum antibiotic treatment, the infection was controlled successfully, and the patient's vision improved. CONCLUSIONS: B. avium can cause infection in the human eye, which can manifest as acute purulent endophthalmitis. Nanopore targeted sequencing technology can quickly identify this organism. Emergency vitrectomy combined with lens removal and silicone oil tamponade and the early application of broad-spectrum antibiotics are key for successful treatment.

Bordetella avium , Bordetella , Cataract Extraction , Endophthalmitis , Endophthalmitis/diagnosis , Endophthalmitis/drug therapy , Endophthalmitis/surgery , Humans , Vitrectomy
Eur J Ophthalmol ; 32(4): 2445-2451, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1354692


OBJECTIVE: To assess the patterns of patient generated aerosol in the context of ophthalmic surgery and ophthalmic examinations. To inform medical teams regarding potential hazards and suggest mitigating measures. METHODS: Qualitatively, real-time time videography assessed exhalation patterns from simulated patients under different clinical scenarios using propylene glycol from an e-cigarette. Quantitatively, high-speed Schlieren imaging was performed to enable high resolution recordings analysable by MATLAB technical computing software. RESULTS: Without a face mask, the standard prior to COVID 19, vapour was observed exiting through the opening in the drape over the surgical field. The amount of vapour increased when a surgical mask was worn. With a taped face mask, the amount of vapour decreased and with inclusion of a continuous suction device, the least amount of vapour was seen. These results were equivocal when the patient was supine or sitting upright. High-speed Schlieren imaging corroborated these findings and in addition showed substantial increase in airflow egress during coughing and with ill-fitting face masks. CONCLUSION: Advising patients to wear a surgical mask at the time of ophthalmic interventions potentially contaminants the ocular field with patient generated aerosol risking endophthalmitis. Surgeon safety can be maintained with personal protective equipment to mitigate the increased egress of vapour from the surgical drape and taping, with or without suction is advisable, whilst meticulous hygiene around lenses is required at the time of slit lamp examination.

COVID-19 , Electronic Nicotine Delivery Systems , Endophthalmitis , Aerosols , COVID-19/prevention & control , Endophthalmitis/surgery , Humans , Personal Protective Equipment
BMC Infect Dis ; 20(1): 849, 2020 Nov 16.
Article in English | MEDLINE | ID: covidwho-1067190


BACKGROUND: Mycobacterium houstonense is rapidly growing mycobacteria (RGM) that belongs to M. fortuitum group. So far, there have been few associated reports of human diseases induced by M. houstonense worldwide. CASE PRESENTATION: We present a delayed-onset postoperative endophthalmitis caused by M. houstonense after glaucoma drainage implant (GDI) surgery. The ocular infection lasted for 2 months without appropriate treatment that developed into endophthalmitis and the patient underwent an emergency enucleation. CONCLUSION: Implant erosion and a delay in diagnosis of ocular infection could lead to irreversible damage as observed in our case. Ophthalmologists should be alert for ocular RGM infection, and prompt laboratory diagnosis with initiation of effective multidrug therapy might prevent loss of vision.

Endophthalmitis/diagnosis , Endophthalmitis/etiology , Glaucoma Drainage Implants/adverse effects , Mycobacteriaceae/genetics , Postoperative Complications/diagnosis , Amikacin/therapeutic use , Anti-Bacterial Agents/therapeutic use , Drug Therapy, Combination , Endophthalmitis/drug therapy , Endophthalmitis/surgery , Eye Enucleation , Follow-Up Studies , Humans , Levofloxacin/therapeutic use , Male , Middle Aged , Mycobacteriaceae/isolation & purification , Postoperative Complications/drug therapy , Postoperative Complications/microbiology , Postoperative Complications/surgery , RNA, Ribosomal, 16S/genetics , RNA, Ribosomal, 23S/genetics , Treatment Outcome