Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 10 de 10
Filter
1.
J Infect Public Health ; 15(7): 746-751, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1885926

ABSTRACT

BACKGROUND: This study aims to assess the neonatal outcomes related to maternal SARS-COV-2 infection. METHODS: In this study, we identified newborns born between May 14 and August 31, 2020, to mothers who were PCR-SRAS-CoV-2 positive at the time of delivery. From the cohort of 974 infants, we performed a nested case-control study. RESULTS: During the study period, 133 (13.7%) mothers were positive for SARS-CoV-2. Among the 35 pregnant women with COVID-19 symptoms (26.3%), cough was the most common symptom, present in half of the cases. Four of them have progressed to critical pneumonia requiring transfer to intensive care unit. The neonates from mothers with positive SARS-CoV-2-RT-PCR, were routinely tested for COVID-19 within the first 24 h after labor, and 3 other newborns tested in the presence of symptoms. There was no significant difference between the two groups with respect to preterm birth, meconium-stained amniotic fluid distress, and neonatal asphyxia. Most infants were breastfed at birth, regardless of their mothers' COVID-19 status. In COVID-19-positive pregnant women admitted to intensive care unit, the proportion of preterm births (OR=12.5 [1.7-90.5]), fetal death in utero (OR=25.9 [2.2-305]) and admission in neonatal intensive care unit admission (OR=13.4 [3.0-60]), appeared higher than the controls. No maternal deaths were recorded. CONCLUSIONS: Our data suggest little neonatal morbidity associated with maternal COVID-19, except for those born to mothers admitted to intensive care unit. However, under breastfeeding conditions with rigorous hygiene precautions and parental education, the risk of transmission of SARS-COV-2 virus to the newborn was very low.


Subject(s)
COVID-19 , Pregnancy Complications, Infectious , Premature Birth , COVID-19/epidemiology , Case-Control Studies , Female , French Guiana/epidemiology , Humans , Infant , Infant, Newborn , Infectious Disease Transmission, Vertical/prevention & control , Pregnancy , Pregnancy Complications, Infectious/diagnosis , Pregnancy Complications, Infectious/epidemiology , Pregnancy Outcome , Premature Birth/epidemiology , SARS-CoV-2
2.
Rev Soc Bras Med Trop ; 55: e02742021, 2022.
Article in English | MEDLINE | ID: covidwho-1833806

ABSTRACT

BACKGROUND: French Guiana (FG) is an ultra-peripheral European region in the Amazon, and the COVID-19 epidemic has had very different kinetics from both its giant neighbors, Brazil or mainland France. METHODS: This study summarized the epidemics of COVID-19 in FG. RESULTS: The tropical climate, multiethnicity, and remoteness of the population forced healthcare providers to accordingly adapt the management of the epidemic. Incidence and mortality have been lower than that in Europe and Latin America due to a combination of prevalence of the youth in the population and highly developed healthcare system. CONCLUSIONS: Currently, vaccine hesitancy hinders the rapid expansion of vaccine coverage.


Subject(s)
COVID-19 , Epidemics , Adolescent , Brazil , COVID-19/epidemiology , Europe , French Guiana/epidemiology , Humans
3.
Infect Genet Evol ; 99: 105243, 2022 04.
Article in English | MEDLINE | ID: covidwho-1763893

ABSTRACT

Mayaro Virus is an emerging arbovirus which can be responsible of important outbreaks in tropical regions. A retrospective study was performed in French Guiana, an ultraperipheral region of Europe in Amazonia. We identified 17 human cases between 2003 and 2019. The clinical and biological picture was close to Chikungunya with fever and arthralgia. One patient had acute meningo-encephalitis, and 4 had persistent arthralgia. Physicians should be aware of this virus, as imported cases in Europe have already occurred. AUTHOR SUMMARY: Latin America has experienced several epidemics of arboviruses in recent years, some known for a long time, such as the dengue virus, and others of more recent introduction such as the chikungunya or Zika viruses. There are other arboviruses for the moment more discreet which are rife with low noise in several countries of the continent, such as the Mayaro virus. This alphavirus, with a presentation similar to that of the chikungunya virus, is currently confined to transmission by forest mosquitoes, but its potential to be transmitted by coastal mosquitoes such as Aedes aegypti, make it a potential candidate for a continent-wide epidemic. It therefore seems necessary to know this virus as well as possible in order to anticipate the occurrence of a possible new epidemic. We present here a both demographic and clinical study of this endemic arbovirus disease in French Guiana.


Subject(s)
Aedes , Arboviruses , Chikungunya Fever , Chikungunya virus , Zika Virus Infection , Zika Virus , Animals , Arthralgia , Cross-Sectional Studies , French Guiana/epidemiology , Humans , Mosquito Vectors , Retrospective Studies , Zika Virus Infection/epidemiology
4.
Soc Sci Med ; 296: 114747, 2022 03.
Article in English | MEDLINE | ID: covidwho-1655166

ABSTRACT

Worldwide, the socioeconomic impacts of COVID-19 disproportionally affect vulnerable groups in society. This paper assesses responses to, and impacts of, the pandemic among mobile migrant populations who work in Artisanal and Small-scale Gold Mining (ASGM) in Suriname and French Guiana. These populations are characterized by poverty, informal or illegal status, and limited access to health care and information. Field research in Suriname (November 2020-January 2021) and French Guiana (January, May, June 2021) included qualitative interviews, informal conversations and observations, and a quantitative survey with 361 men and women in ASGM communities. Contrary to reports from the ASGM sector elsewhere, interviewed inhabitants of ASGM areas in Suriname and French Guiana showed little concern about COVID-19. Respondents reported feeling safer in the forest where they work than in the urban areas or in their home country. Trust in home remedies and over-the-counter pharmaceuticals further reduced anxiety about the pandemic. Three-quarters of survey respondents reported that the COVID-19 pandemic had not affected their work or income at all. The researchers conclude that in these remote Amazon communities, responses to COVID-19 mirror attitudes and behavior vis-à-vis malaria and other health risks: self-medicate, ignore, and pray. Living on the margins of society mitigates the socioeconomic impacts of COVID-19, as containment measures are not applied to these socially invisible populations. Whereas the urban poor are severely hit by the pandemic, this hidden population benefits from high gold prices, an outdoors lifestyle, and traditional resourcefulness in dealing with a life full of risks.


Subject(s)
COVID-19 , Transients and Migrants , COVID-19/epidemiology , Female , French Guiana/epidemiology , Gold , Humans , Male , Mining , Pandemics , SARS-CoV-2 , Suriname/epidemiology
5.
PLoS Negl Trop Dis ; 15(11): e0009945, 2021 11.
Article in English | MEDLINE | ID: covidwho-1518351

ABSTRACT

BACKGROUND: While Latin America has been heavily affected by the pandemic, only a few seroprevalence studies have been conducted there during the first epidemic wave in the first half of 2020. METHODOLOGY/PRINCIPAL FINDINGS: A cross-sectional survey was performed between 15 July 2020 and 23 July 2020 among individuals who visited 4 medical laboratories or 5 health centers for routine screening or clinical management, with the exception of symptomatic suggestive cases of covid-19. Samples were screened for the presence of anti-SARS-CoV-2 IgG directed against domain S1 of the SARS-CoV-2 spike protein using the anti-SARS-CoV-2 enzyme-linked immunosorbent assay (ELISA) from Euroimmun. CONCLUSIONS/SIGNIFICANCE: The overall seroprevalence was 15.4% [9.3%-24.4%] among 480 participants, ranging from 4.0% to 25.5% across the different municipalities. The seroprevalence did not differ according to gender (p = 0.19) or age (p = 0.51). Among SARS-CoV-2 positive individuals, we found that 24.6% [11.5%-45.2%] reported symptoms consistent with COVID-19. Our findings revealed high levels of infection across the territory but a low number of resulting deaths, which can be explained by French Guiana's young population structure.


Subject(s)
Antibodies, Viral/blood , COVID-19/epidemiology , Immunoglobulin G/blood , SARS-CoV-2/immunology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Cross-Sectional Studies , French Guiana/epidemiology , Humans , Infant , Middle Aged , Seroepidemiologic Studies , Young Adult
6.
Emerg Infect Dis ; 27(10): 2673-2676, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1486742

ABSTRACT

An outbreak of severe acute respiratory syndrome coronavirus 2 caused by the Gamma variant of concern infected 24/44 (55%) employees of a gold mine in French Guiana (87% symptomatic, no severe forms). The attack rate was 60% (15/25) among fully vaccinated miners and 75% (3/4) among unvaccinated miners without a history of infection.


Subject(s)
COVID-19 , SARS-CoV-2 , French Guiana/epidemiology , Gold , Humans
7.
Br J Nurs ; 30(9): 540-546, 2021 May 13.
Article in English | MEDLINE | ID: covidwho-1227189

ABSTRACT

BACKGROUND: In emergency departments (EDs), the staff continually face stressful situations requiring staff to adopt various coping strategies. AIMS: The study aimed to assess work-related stress in ED during the COVID-19 outbreak. METHOD: The study was a monocentric investigation based on a questionnaire survey that elicits general information and uses the Karasek model to analyse the data. FINDINGS: A total of 117 forms were collected for analysis. The score for decision latitude (or autonomy and skills at work) was 70 (IQR: 64-74) and the score for psychological demand was 25 (IQR: 23-27). The score for social support by the management team was 11 (IQR: 9-12) and the score for social support by colleagues 12 (IQR: 10-12). Of the total number of respondents, job strain was assessed as affecting 24.8%. CONCLUSION: The study shows high levels of stress among the ED workforce. The findings indicate that it is imperative to develop simple management tools that are capable of measuring the internal causes of stress in order to develop an adapted wellness programme in ED.


Subject(s)
COVID-19 , Disease Outbreaks , Emergency Service, Hospital , Nursing Staff, Hospital , Occupational Stress , COVID-19/epidemiology , COVID-19/nursing , French Guiana/epidemiology , Humans , Nursing Staff, Hospital/psychology , Occupational Stress/epidemiology , Surveys and Questionnaires
8.
Front Public Health ; 9: 586299, 2021.
Article in English | MEDLINE | ID: covidwho-1156164

ABSTRACT

Background: The COVID 19 epidemic submerged many health systems in the Amazon. The objective of the present study was to focus on the epidemic curves of the COVID 19 epidemic in different centers, and to look at testing and mortality data. Methods: Publicly available datasets were used. The log10 of the daily cumulated number of cases starting from the day the territory reached 100 cumulated cases was plotted to compare the magnitude, shape and slope of the different curves. The maximum daily testing efforts were plotted for each territory in relation to the maximum daily number of diagnoses. The case fatality rate was computed by dividing the number of COVID 19 deaths by the number of confirmed cases. Results: In the Amazonian regions in general the speed of growth was generally lower than in Europe or the USA, or Southern Brazil. Whereas, countries like South Korea or New Zealand "broke" the curve relatively rapidly the log linear trajectory seemed much longer with signs of a decline in growth rate as of early July 2020. After a very slow start, French Guiana had the lowest slope when compared to other Amazonian territories with significant epidemics. The Amazonian states of Roraima, Amazonas, Parà, and Amapà had among the highest number of cases and deaths per million inhabitants in the world. French Guiana had significantly fewer deaths relative to its number of confirmed cases than other Amazonian territories. French Guiana had a late epidemic surge with intense testing scale-up often exceeding 4,000 persons tested daily per million inhabitants. Brazil was an outlier with low daily testing levels in relation to the number of daily diagnoses. Conclusions: There were marked heterogeneities mortality rates suggesting that socioeconomic, political factors, and perhaps ethnic vulnerability led to striking outcome differences in this Amazonian context.


Subject(s)
COVID-19/epidemiology , COVID-19/mortality , Cause of Death , Disease Outbreaks/statistics & numerical data , Epidemics/statistics & numerical data , Internationality , Brazil/epidemiology , Europe/epidemiology , French Guiana/epidemiology , Humans , North America/epidemiology , SARS-CoV-2
9.
Nat Commun ; 12(1): 1634, 2021 03 12.
Article in English | MEDLINE | ID: covidwho-1132074

ABSTRACT

While general lockdowns have proven effective to control SARS-CoV-2 epidemics, they come with enormous costs for society. It is therefore essential to identify control strategies with lower social and economic impact. Here, we report and evaluate the control strategy implemented during a large SARS-CoV-2 epidemic in June-July 2020 in French Guiana that relied on curfews, targeted lockdowns, and other measures. We find that the combination of these interventions coincided with a reduction in the basic reproduction number of SARS-CoV-2 from 1.7 to 1.1, which was sufficient to avoid hospital saturation. We estimate that thanks to the young demographics, the risk of hospitalisation following infection was 0.3 times that of metropolitan France and that about 20% of the population was infected by July. Our model projections are consistent with a recent seroprevalence study. The study showcases how mathematical modelling can be used to support healthcare planning in a context of high uncertainty.


Subject(s)
COVID-19/prevention & control , COVID-19/transmission , Pandemics , Quarantine/methods , SARS-CoV-2 , Adolescent , Adult , Aged , Aged, 80 and over , Basic Reproduction Number/prevention & control , Basic Reproduction Number/statistics & numerical data , COVID-19/epidemiology , Child , Child, Preschool , Female , French Guiana/epidemiology , Hospitalization/statistics & numerical data , Hospitalization/trends , Humans , Infant , Infant, Newborn , Male , Middle Aged , Models, Statistical , Pandemics/prevention & control , Pandemics/statistics & numerical data , Quarantine/statistics & numerical data , Quarantine/trends , Young Adult
10.
Eur J Obstet Gynecol Reprod Biol ; 257: 11-18, 2021 Feb.
Article in English | MEDLINE | ID: covidwho-1116622

ABSTRACT

OBJECTIVE: To describe the proportions of asymptomatic, mild and severe diseases in infected pregnant women admitted for delivery. To compare maternal, fetal and neonatal outcomes of SARS-CoV-2 infected pregnant women with those of non-infected patients. STUDY DESIGN: Through an universal PCR testing for SARS-COV-2 at admission (not symptoms-based), this prospective cohort study enrolled all pregnant women admitted for delivery between 16th of June and the 16th of August 2020 in the West French Guiana Hospital Center. RESULTS: 507 pregnant women were included during the study period, of which 137 (27 %) were infected with SARS-COV-2. On admission, only 34/137 (24.8 %) of these patients presented with clinical symptoms. Among asymptomatic women, 16 /103 (15 %) became symptomatic after diagnosis. Throughout the delivery hospitalization and follow-up, 87/137 (63.5 %) remained always asymptomatic, 45/137 (32.8 %) developed a mild COVID-19 and 5/137 (3.6 %) developed a severe infection. SARS-CoV-2 infected patients were more likely to have post-partum hemorrhage >500 mL (14.2 % vs 7.2 %, RR 2.0 [95 %CI 1.1-3.4]), to be transfused (5.5 % vs 1.1 %, RR 4.9 [1.5-16.6]), and to be hospitalized in ICU (3.6 % vs 0.8 %, RR 4.5 [95 %CI 1.1-18.6] than uninfected ones. Intra-uterine fetal demises were more common in infected mothers compared to controls (5.1 % vs 1.1 %, RR 4.7 [95 % CI 1.4-45.9). Among 108 neonates from infected mothers tested at birth, none tested positive (0/108). When tested between 25 and 42 h after delivery, 4/29 (13.7 %) were positive for SARS-CoV-2 RT-PCR on nasopharyngeal swabs and remained asymptomatic. CONCLUSION: Pregnant women admitted for delivery and diagnosed with a SARS-COV-2 infection through an universal screening were symptomatic in only a quarter of cases. Their risks of post-partum hemorrhage, transfusion and admission to ICU were higher than those of uninfected patients. They also presented a higher risk of intra-uterine fetal demise. There were no other differences in maternal, obstetrical or neonatal outcomes.


Subject(s)
Asymptomatic Infections , COVID-19 Testing , COVID-19/diagnosis , Pregnancy Complications, Infectious/diagnosis , Severity of Illness Index , Adult , COVID-19/epidemiology , COVID-19/therapy , COVID-19/transmission , Female , Follow-Up Studies , French Guiana/epidemiology , Humans , Infant, Newborn , Infectious Disease Transmission, Vertical/statistics & numerical data , Male , Pregnancy , Pregnancy Complications, Infectious/epidemiology , Pregnancy Complications, Infectious/therapy , Prognosis , Prospective Studies , Stillbirth/epidemiology
SELECTION OF CITATIONS
SEARCH DETAIL