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J Cosmet Dermatol ; 19(12): 3168-3170, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-808315

ABSTRACT

BACKGROUND: COVID-19 due to SARS-CoV-2 was first described in the city of Wuhan in China and spread around the world turning into a pandemic. COVID-19 can affect different organ systems, including the oral mucosa. AIMS: Although cutaneous involvement has been defined in association with COVID-19, the number of case reports about mucosal involvement by SARS-CoV-2 is limited. Hereby, we report a case of hemorrhagic necrosis on the lip in a patient with paroxysmal nocturnal hemoglobinuria (PNH) and COVID-19 infection and briefly discuss its possible mechanism. PATIENTS: The clinical features and causes of hemorrhagic necrosis on the lip in a woman are presented. RESULTS: In our patient, we think that PNH-associated dermal micro-occlusions caused extensive painful necrosis of the lip. Additionally, COVID-19-induced endothelial damage helped to develop exaggerated hemorrhagic necrosis. CONCLUSION: This current case presentation will contribute to the literature as another case with COVID-19 triggering mucosal involvement.


Subject(s)
COVID-19/complications , Hemoglobinuria, Paroxysmal/complications , Lip/pathology , Aged , COVID-19/pathology , Female , Hemoglobinuria, Paroxysmal/pathology , Humans , Necrosis/diagnosis , Necrosis/etiology , Necrosis/therapy
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