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Adv Food Nutr Res ; 96: 417-429, 2021.
Article in English | MEDLINE | ID: covidwho-1265623


Selenium (Se) is an element commonly found in the environment at different levels. Its compounds are found in soil, water, and air. This element is also present in raw materials of plant and animal origin, so it can be introduced into human organisms through food. Selenium is a cofactor of enzymes responsible for the antioxidant protection of the body and plays an important role in regulating inflammatory processes in the body. A deficiency in selenium is associated with a number of viral diseases, including COVID-19. This element, taken in excess, may have a toxic effect in the form of joint diseases and diseases of the blood system. Persistent selenium deficiency in the body may also impact infertility, and in such cases supplementation is needed.

COVID-19/blood , Nutritional Status , Selenium/blood , COVID-19/etiology , Female , Humans , Infertility/blood , Infertility/drug therapy , Infertility/etiology , Male , Selenium/deficiency , Selenium/therapeutic use , Selenium/toxicity , Virus Diseases/blood , Virus Diseases/etiology
PLoS One ; 15(9): e0239253, 2020.
Article in English | MEDLINE | ID: covidwho-781669


PURPOSE: To examine the psychological impact of fertility treatment suspensions resulting from the COVID-19 pandemic and to clarify psychosocial predictors of better or worse mental health. METHODS: 92 women from Canada and the United States (ages 20-45 years) whose fertility treatments had been cancelled were recruited via social media. Participants completed a battery of questionnaires assessing depressive symptoms, perceived mental health impact, and change in quality of life related to treatment suspensions. Potential predictors of psychological outcomes were also examined, including several personality traits, aspects of social support, illness cognitions, and coping strategies. RESULTS: 52% of respondents endorsed clinical levels of depressive symptoms. On a 7-point scale, participants endorsed a significant decline in overall quality of life (M(SD) = -1.3(1.3), p < .0001) as well as a significant decline in mental health related to treatment suspensions on a scale from -5 to +5 (M(SD) = -2.1(2.1), p < .001). Several psychosocial variables were found to positively influence these outcomes: lower levels of defensive pessimism (r = -.25, p < .05), greater infertility acceptance (r = .51, p < .0001), better quality social support (r = .31, p < .01), more social support seeking (r = .35, p < .001) and less avoidance of infertility reminders (r = -.23, p = .029). CONCLUSION: Fertility treatment suspensions have had a considerable negative impact on women's mental health and quality of life. However, these findings point to several protective psychosocial factors that can be fostered in the future to help women cope.

Betacoronavirus , Coronavirus Infections/psychology , Infertility/drug therapy , Pneumonia, Viral/psychology , Withholding Treatment , Adult , COVID-19 , Canada/epidemiology , Female , Fertility Agents, Female/supply & distribution , Fertility Agents, Female/therapeutic use , Humans , Infertility/psychology , Mental Health , Middle Aged , Pandemics , Quality of Life/psychology , SARS-CoV-2 , Surveys and Questionnaires , United States/epidemiology , Young Adult
J Assist Reprod Genet ; 37(8): 1831-1835, 2020 Aug.
Article in English | MEDLINE | ID: covidwho-638847


Various fertility scientific societies have published pathways and recommendations for COVID-19 screening during fertility treatments. As there is currently very limited research evidence on how to best deliver this screening, it is not surprising that there are noticeable differences between their recommendations. This paper compares the screening pathways recommended by these guidelines, in the light of the emerging evidence. It proposes the more liberal use of viral testing for improving detection of asymptomatic or mildly symptomatic fertility patients. It also argues that a negative test result on symptomatic individuals should not be over-relied upon for allowing the treatment to proceed. In these cases, a low threshold for cancellation may still need to be maintained.

Betacoronavirus/isolation & purification , Coronavirus Infections/diagnosis , Coronavirus Infections/transmission , Infertility/drug therapy , Infertility/virology , Pneumonia, Viral/diagnosis , Pneumonia, Viral/transmission , Practice Guidelines as Topic/standards , COVID-19 , Coronavirus Infections/drug therapy , Coronavirus Infections/virology , Humans , Pandemics , Pneumonia, Viral/virology , SARS-CoV-2