Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 403
Filter
1.
Comb Chem High Throughput Screen ; 25(4): 634-641, 2022.
Article in English | MEDLINE | ID: covidwho-1817778

ABSTRACT

BACKGROUND: Drug development requires a lot of money and time, and the outcome of the challenge is unknown. So, there is an urgent need for researchers to find a new approach that can reduce costs. Therefore, the identification of drug-target interactions (DTIs) has been a critical step in the early stages of drug discovery. These computational methods aim to narrow the search space for novel DTIs and to elucidate the functional background of drugs. Most of the methods developed so far use binary classification to predict the presence or absence of interactions between the drug and the target. However, it is more informative but also more challenging to predict the strength of the binding between a drug and its target. If the strength is not strong enough, such a DTI may not be useful. Hence, the development of methods to predict drug-target affinity (DTA) is of significant importance Method: We have improved the GraphDTA model from a dual-channel model to a triple-channel model. We interpreted the target/protein sequences as time series and extracted their features using the LSTM network. For the drug, we considered both the molecular structure and the local chemical background, retaining the four variant networks used in GraphDTA to extract the topological features of the drug and capturing the local chemical background of the atoms in the drug by using BiGRU. Thus, we obtained the latent features of the target and two latent features of the drug. The connection of these three feature vectors is then inputted into a 2 layer FC network, and a valuable binding affinity is the output. RESULT: We used the Davis and Kiba datasets, using 80% of the data for training and 20% of the data for validation. Our model showed better performance when compared with the experimental results of GraphDTA Conclusion: In this paper, we altered the GraphDTA model to predict drug-target affinity. It represents the drug as a graph and extracts the two-dimensional drug information using a graph convolutional neural network. Simultaneously, the drug and protein targets are represented as a word vector, and the convolutional neural network is used to extract the time-series information of the drug and the target. We demonstrate that our improved method has better performance than the original method. In particular, our model has better performance in the evaluation of benchmark databases.


Subject(s)
Drug Development , Neural Networks, Computer , Amino Acid Sequence , Drug Interactions , Molecular Structure
2.
J Healthc Eng ; 2022: 9581387, 2022.
Article in English | MEDLINE | ID: covidwho-1779440

ABSTRACT

Prior to COVID-19, the tourism industry was one of the important sectors of the world economy. This study intends to measure the perception of Chinese tourists concerning the spread of COVID-19 in China. The crowding perception, xenophobia, and ethnocentrism are the measurement indicators of the study. A five-point Likert scale is used to predict the perception of the tourists in various destinations. The Kaiser-Mayer-Olkin test and Cronbach's alpha are conducted to ensure the validity and reliability of the corresponding items. SPSS version 21 is used to obtain factor loading, mean values, and standard deviation. Regression analysis is used to measure the strength of the constructs' relationship and prove the hypotheses. Questionnaires have been filled from 730 Chinese respondents. Artificial neural networks and confusion matrices are used for validation and performance evaluation, respectively. Results show that crowding perception, xenophobia, and ethnocentrism caused the spread of COVID-19 during the epidemic. Hence, the tourism industry in China is adversely affected by COVID-19. The crisis management stakeholders of the country need to adopt policies to reduce the spread of COVID-19. The tourism sector needs to provide confidence to the tourists. It will provide ground for the mental strength of the tourists in China.


Subject(s)
COVID-19 , COVID-19/epidemiology , China/epidemiology , Humans , Neural Networks, Computer , Reproducibility of Results , Tourism
3.
Comput Math Methods Med ; 2022: 1566727, 2022.
Article in English | MEDLINE | ID: covidwho-1779431

ABSTRACT

Since the outbreak of COVID-19, BRICS countries have experienced different epidemic spread due to different health conditions, social isolation measures, vaccination rates, and other factors. A descriptive analysis is conducted for the spread of the epidemic in the BRICS countries. Considering the nonlinear and nonstationary characteristics of COVID-19 data, a principle of decomposition-reconstruction(R)-prediction-integration is proposed. Correspondingly, this paper constructs an integrated deep learning prediction model of CEEMDAN-R-ILSTM-Elman. Specifically, the prediction model is integrated by complete ensemble empirical mode decomposition (CEEMDAN), improved long-term and short-term memory network (ILSTM), and Elman neural network. First, the data is decomposed by adopting CEEMDAN. Then, by calculating the permutation entropy and average period, the decomposed eigenmode component IMFs are reconstructed into four sequences of high, medium, low level, and trend term. Thus, ILSTM and Elman algorithms are used for component sequence prediction, whose results are integrated as the final results. The ILSTM is established based on the LSTM model and the improved beetle antennae search algorithm (IBAS). The ILSTM mainly considers that the prediction accuracy of LSTM model is vulnerable to the influence of parameter selection. The IBAS with adaptive step size is used to automatically optimize the super parameters of LSTM model and to improve the modeling efficiency and prediction accuracy. Experimental results indicate that compared with other benchmark models, CEEMDAN-R-ILSTM-Elman integrated model predicts the number of newly confirmed cases of COVID-19 in BRICS countries with higher accuracy and lower error. Strict social policies have a greater impact on the infection rate and mortality rate of the epidemic. During July-August 2021, epidemic spread in BRICS countries will slow down, and the overall situation is still quite severe.


Subject(s)
COVID-19 , Deep Learning , Algorithms , COVID-19/epidemiology , Humans , Neural Networks, Computer
4.
Front Public Health ; 10: 861062, 2022.
Article in English | MEDLINE | ID: covidwho-1776092

ABSTRACT

Background and Objective: According to the WHO, diabetes mellitus is a long-term condition marked by high blood sugar levels. The consequences might be far-reaching. According to current increases in mortality, diabetes has risen to number 10 among the leading causes of mortality worldwide. When used to predict diabetes using unbalanced datasets from testing, machine learning (ML) classifiers and established approaches for encoding categorical data have exhibited a broad variety of surprising outcomes. Early studies also made use of an artificial neural network to extract features without obtaining a grasp of the sequence information. Methods: This study offers a deep learning-based decision support system (DSS), utilizing bidirectional long/short-term memory (BiLSTM), to accurately predict diabetic illness from patient data. In order to predict diabetes, the BiLSTM hybrid model was used after balancing the data set. Results: Unlike earlier studies, this proposed model's trial findings were promising, with an accuracy of 93.07%, 93% precision, 92% recall, and a 92% F1-score. Conclusions: Using a BILSTM model for classification outperforms current approaches in the diabetes detection domain.


Subject(s)
Diabetes Mellitus , Algorithms , Decision Support Systems, Clinical , Diabetes Mellitus/diagnosis , Humans , Machine Learning , Neural Networks, Computer
5.
Front Public Health ; 10: 858327, 2022.
Article in English | MEDLINE | ID: covidwho-1776086

ABSTRACT

Early detection of vessels from fundus images can effectively prevent the permanent retinal damages caused by retinopathies such as glaucoma, hyperextension, and diabetes. Concerning the red color of both retinal vessels and background and the vessel's morphological variations, the current vessel detection methodologies fail to segment thin vessels and discriminate them in the regions where permanent retinopathies mainly occur. This research aims to suggest a novel approach to take the benefit of both traditional template-matching methods with recent deep learning (DL) solutions. These two methods are combined in which the response of a Cauchy matched filter is used to replace the noisy red channel of the fundus images. Consequently, a U-shaped fully connected convolutional neural network (U-net) is employed to train end-to-end segmentation of pixels into vessel and background classes. Each preprocessed image is divided into several patches to provide enough training images and speed up the training per each instance. The DRIVE public database has been analyzed to test the proposed method, and metrics such as Accuracy, Precision, Sensitivity and Specificity have been measured for evaluation. The evaluation indicates that the average extraction accuracy of the proposed model is 0.9640 on the employed dataset.


Subject(s)
Algorithms , Retinal Vessels/diagnostic imaging , Fundus Oculi , Humans , Neural Networks, Computer , Retinal Vessels/anatomy & histology
6.
J Healthc Eng ; 2022: 1773259, 2022.
Article in English | MEDLINE | ID: covidwho-1775006

ABSTRACT

Automated disease prediction has now become a key concern in medical research due to exponential population growth. The automated disease identification framework aids physicians in diagnosing disease, which delivers accurate disease prediction that provides rapid outcomes and decreases the mortality rate. The spread of Coronavirus disease 2019 (COVID-19) has a significant effect on public health and the everyday lives of individuals currently residing in more than 100 nations. Despite effective attempts to reach an appropriate trend to forecast COVID-19, the origin and mutation of the virus is a crucial obstacle in the diagnosis of the detected cases. Even so, the development of a model to forecast COVID-19 from chest X-ray (CXR) and computerized tomography (CT) images with the correct decision is critical to assist with intelligent detection. In this paper, a proposed hybrid model of the artificial neural network (ANN) with parameters optimization by the butterfly optimization algorithm has been introduced. The proposed model was compared with the pretrained AlexNet, GoogLeNet, and the SVM to identify the publicly accessible COVID-19 chest X-ray and CT images. There were six datasets for the examinations: three datasets with X-ray pictures and three with CT images. The experimental results approved the superiority of the proposed model for cognitive COVID-19 pattern recognition with average accuracy 90.48, 81.09, 86.76, and 84.97% for the proposed model, support vector machine (SVM), AlexNet, and GoogLeNet, respectively.


Subject(s)
COVID-19 , Algorithms , Cognition , Humans , Neural Networks, Computer , Support Vector Machine
7.
PLoS One ; 17(3): e0265691, 2022.
Article in English | MEDLINE | ID: covidwho-1770752

ABSTRACT

Automatic detection of some pulmonary abnormalities using chest X-rays may be impacted adversely due to obscuring by bony structures like the ribs and the clavicles. Automated bone suppression methods would increase soft tissue visibility and enhance automated disease detection. We evaluate this hypothesis using a custom ensemble of convolutional neural network models, which we call DeBoNet, that suppresses bones in frontal CXRs. First, we train and evaluate variants of U-Nets, Feature Pyramid Networks, and other proposed custom models using a private collection of CXR images and their bone-suppressed counterparts. The DeBoNet, constructed using the top-3 performing models, outperformed the individual models in terms of peak signal-to-noise ratio (PSNR) (36.7977±1.6207), multi-scale structural similarity index measure (MS-SSIM) (0.9848±0.0073), and other metrics. Next, the best-performing bone-suppression model is applied to CXR images that are pooled from several sources, showing no abnormality and other findings consistent with COVID-19. The impact of bone suppression is demonstrated by evaluating the gain in performance in detecting pulmonary abnormality consistent with COVID-19 disease. We observe that the model trained on bone-suppressed CXRs (MCC: 0.9645, 95% confidence interval (0.9510, 0.9780)) significantly outperformed (p < 0.05) the model trained on non-bone-suppressed images (MCC: 0.7961, 95% confidence interval (0.7667, 0.8255)) in detecting findings consistent with COVID-19 indicating benefits derived from automatic bone suppression on disease classification. The code is available at https://github.com/sivaramakrishnan-rajaraman/Bone-Suppresion-Ensemble.


Subject(s)
COVID-19 , Lung Diseases , COVID-19/diagnostic imaging , Humans , Neural Networks, Computer , Radiography, Thoracic/methods , Ribs , Signal-To-Noise Ratio
8.
J Xray Sci Technol ; 30(2): 365-376, 2022.
Article in English | MEDLINE | ID: covidwho-1771015

ABSTRACT

BACKGROUND: Chest X-ray images are widely used to detect many different lung diseases. However, reading chest X-ray images to accurately detect and classify different lung diseases by doctors is often difficult with large inter-reader variability. Thus, there is a huge demand for developing computer-aided automated schemes of chest X-ray images to help doctors more accurately and efficiently detect lung diseases depicting on chest X-ray images. OBJECTIVE: To develop convolution neural network (CNN) based deep learning models and compare their feasibility and performance to classify 14 chest diseases or pathology patterns based on chest X-rays. METHOD: Several CNN models pre-trained using ImageNet dataset are modified as transfer learning models and applied to classify between 14 different chest pathology and normal chest patterns depicting on chest X-ray images. In this process, a deep convolution generative adversarial network (DC-GAN) is also trained to mitigate the effects of small or imbalanced dataset and generate synthetic images to balance the dataset of different diseases. The classification models are trained and tested using a large dataset involving 91,324 frontal-view chest X-ray images. RESULTS: In this study, eight models are trained and compared. Among them, ResNet-152 model achieves an accuracy of 67% and 62% with and without data augmentation, respectively. Inception-V3, NasNetLarge, Xcaption, ResNet-50 and InceptionResNetV2 achieve accuracy of 68%, 62%, 66%, 66% and 54% respectively. Additionally, Resnet-152 with data augmentation achieves an accuracy of 83% but only for six classes. CONCLUSION: This study solves the problem of having fewer data by using GAN-based techniques to add synthetic images and demonstrates the feasibility of applying transfer learning CNN method to help classify 14 types of chest diseases depicting on chest X-ray images.


Subject(s)
COVID-19 , Deep Learning , Algorithms , Humans , Neural Networks, Computer , SARS-CoV-2 , X-Rays
9.
J Healthc Eng ; 2022: 5329014, 2022.
Article in English | MEDLINE | ID: covidwho-1770038

ABSTRACT

Coronavirus disease 2019 (COVID-19) is a novel disease that affects healthcare on a global scale and cannot be ignored because of its high fatality rate. Computed tomography (CT) images are presently being employed to assist doctors in detecting COVID-19 in its early stages. In several scenarios, a combination of epidemiological criteria (contact during the incubation period), the existence of clinical symptoms, laboratory tests (nucleic acid amplification tests), and clinical imaging-based tests are used to diagnose COVID-19. This method can miss patients and cause more complications. Deep learning is one of the techniques that has been proven to be prominent and reliable in several diagnostic domains involving medical imaging. This study utilizes a convolutional neural network (CNN), stacked autoencoder, and deep neural network to develop a COVID-19 diagnostic system. In this system, classification undergoes some modification before applying the three CT image techniques to determine normal and COVID-19 cases. A large-scale and challenging CT image dataset was used in the training process of the employed deep learning model and reporting their final performance. Experimental outcomes show that the highest accuracy rate was achieved using the CNN model with an accuracy of 88.30%, a sensitivity of 87.65%, and a specificity of 87.97%. Furthermore, the proposed system has outperformed the current existing state-of-the-art models in detecting the COVID-19 virus using CT images.


Subject(s)
COVID-19 , Deep Learning , COVID-19/diagnostic imaging , Humans , Neural Networks, Computer , Tomography, X-Ray Computed/methods
10.
Comput Intell Neurosci ; 2022: 2103975, 2022.
Article in English | MEDLINE | ID: covidwho-1759493

ABSTRACT

The drones can be used to detect a group of people who are unmasked and do not maintain social distance. In this paper, a deep learning-enabled drone is designed for mask detection and social distance monitoring. A drone is one of the unmanned systems that can be automated. This system mainly focuses on Industrial Internet of Things (IIoT) monitoring using Raspberry Pi 4. This drone automation system sends alerts to the people via speaker for maintaining the social distance. This system captures images and detects unmasked persons using faster regions with convolutional neural network (faster R-CNN) model. When the system detects unmasked persons, it sends their details to respective authorities and the nearest police station. The built model covers the majority of face detection using different benchmark datasets. OpenCV camera utilizes 24/7 service reports on a daily basis using Raspberry Pi 4 and a faster R-CNN algorithm.


Subject(s)
Internet of Things , Algorithms , Humans , Neural Networks, Computer
11.
Tomography ; 8(2): 869-890, 2022 03 21.
Article in English | MEDLINE | ID: covidwho-1753687

ABSTRACT

The automatic recognition of COVID-19 diseases is critical in the present pandemic since it relieves healthcare staff of the burden of screening for infection with COVID-19. Previous studies have proven that deep learning algorithms can be utilized to aid in the diagnosis of patients with potential COVID-19 infection. However, the accuracy of current COVID-19 recognition models is relatively low. Motivated by this fact, we propose three deep learning architectures, F-EDNC, FC-EDNC, and O-EDNC, to quickly and accurately detect COVID-19 infections from chest computed tomography (CT) images. Sixteen deep learning neural networks have been modified and trained to recognize COVID-19 patients using transfer learning and 2458 CT chest images. The proposed EDNC has then been developed using three of sixteen modified pre-trained models to improve the performance of COVID-19 recognition. The results suggested that the F-EDNC method significantly enhanced the recognition of COVID-19 infections with 97.75% accuracy, followed by FC-EDNC and O-EDNC (97.55% and 96.12%, respectively), which is superior to most of the current COVID-19 recognition models. Furthermore, a localhost web application has been built that enables users to easily upload their chest CT scans and obtain their COVID-19 results automatically. This accurate, fast, and automatic COVID-19 recognition system will relieve the stress of medical professionals for screening COVID-19 infections.


Subject(s)
COVID-19 , Deep Learning , Algorithms , COVID-19/diagnostic imaging , Humans , Neural Networks, Computer , Tomography, X-Ray Computed/methods
12.
J Healthc Eng ; 2022: 4130674, 2022.
Article in English | MEDLINE | ID: covidwho-1745632

ABSTRACT

Intelligent decision support systems (IDSS) for complex healthcare applications aim to examine a large quantity of complex healthcare data to assist doctors, researchers, pathologists, and other healthcare professionals. A decision support system (DSS) is an intelligent system that provides improved assistance in various stages of health-related disease diagnosis. At the same time, the SARS-CoV-2 infection that causes COVID-19 disease has spread globally from the beginning of 2020. Several research works reported that the imaging pattern based on computed tomography (CT) can be utilized to detect SARS-CoV-2. Earlier identification and detection of the diseases is essential to offer adequate treatment and avoid the severity of the disease. With this motivation, this study develops an efficient deep-learning-based fusion model with swarm intelligence (EDLFM-SI) for SARS-CoV-2 identification. The proposed EDLFM-SI technique aims to detect and classify the SARS-CoV-2 infection or not. Also, the EDLFM-SI technique comprises various processes, namely, data augmentation, preprocessing, feature extraction, and classification. Moreover, a fusion of capsule network (CapsNet) and MobileNet based feature extractors are employed. Besides, a water strider algorithm (WSA) is applied to fine-tune the hyperparameters involved in the DL models. Finally, a cascaded neural network (CNN) classifier is applied for detecting the existence of SARS-CoV-2. In order to showcase the improved performance of the EDLFM-SI technique, a wide range of simulations take place on the COVID-19 CT data set and the SARS-CoV-2 CT scan data set. The simulation outcomes highlighted the supremacy of the EDLFM-SI technique over the recent approaches.


Subject(s)
COVID-19 , Deep Learning , Humans , Intelligence , Neural Networks, Computer , SARS-CoV-2
13.
Technol Cancer Res Treat ; 21: 15330338221085375, 2022.
Article in English | MEDLINE | ID: covidwho-1745537

ABSTRACT

Introduction: Chest computed tomography (CT) is important for the early screening of lung diseases and clinical diagnosis, particularly during the COVID-19 pandemic. We propose a method for classifying peripheral lung cancer and focal pneumonia on chest CT images and undertake 5 window settings to study the effect on the artificial intelligence processing results. Methods: A retrospective collection of CT images from 357 patients with peripheral lung cancer having solitary solid nodule or focal pneumonia with a solitary consolidation was applied. We segmented and aligned the lung parenchyma based on some morphological methods and cropped this region of the lung parenchyma with the minimum 3D bounding box. Using these 3D cropped volumes of all cases, we designed a 3D neural network to classify them into 2 categories. We also compared the classification results of the 3 physicians with different experience levels on the same dataset. Results: We conducted experiments using 5 window settings. After cropping and alignment based on an automatic preprocessing procedure, our neural network achieved an average classification accuracy of 91.596% under a 5-fold cross-validation in the full window, in which the area under the curve (AUC) was 0.946. The classification accuracy and AUC value were 90.48% and 0.957 for the junior physician, 94.96% and 0.989 for the intermediate physician, and 96.92% and 0.980 for the senior physician, respectively. After removing the error prediction, the accuracy improved significantly, reaching 98.79% in the self-defined window2. Conclusion: Using the proposed neural network, in separating peripheral lung cancer and focal pneumonia in chest CT data, we achieved an accuracy competitive to that of a junior physician. Through a data ablation study, the proposed 3D CNN can achieve a slightly higher accuracy compared with senior physicians in the same subset. The self-defined window2 was the best for data training and evaluation.


Subject(s)
COVID-19 , Lung Neoplasms , Artificial Intelligence , COVID-19/diagnostic imaging , Humans , Lung Neoplasms/diagnostic imaging , Neural Networks, Computer , Pandemics , Retrospective Studies , Tomography, X-Ray Computed/methods
14.
BMC Infect Dis ; 22(1): 102, 2022 Jan 29.
Article in English | MEDLINE | ID: covidwho-1745499

ABSTRACT

BACKGROUND: Acquired immunodeficiency syndrome (AIDS) is a malignant infectious disease with high mortality caused by HIV (human immunodeficiency virus, and up to now there are no curable drugs or effective vaccines. In order to understand AIDS's development trend, we establish hybrid EMD-BPNN (empirical modal decomposition and Back-propagation artificial neural network model) model to forecast new HIV infection in Dalian and to evaluate model's performance. METHODS: The monthly HIV data series are decomposed by EMD method, and then all decomposition results are used as training and testing data to establish BPNN model, namely BPNN was fitted to each IMF (intrinsic mode function) and residue separately, and the predicted value is the sum of the predicted values from the models. Meanwhile, using yearly HIV data to established ARIMA and using monthly HIV data to established BPNN, and SARIMA (seasonal autoregressive integrated moving average) model to compare the predictive ability with EMD-BPNN model. RESULTS: From 2004 to 2017, 3310 cases of HIV were reported in Dalian, including 101 fatal cases. The monthly HIV data series are decomposed into four relatively stable IMFs and one residue item by EMD, and the residue item showed that the incidence of HIV increases firstly after declining. The mean absolute percentage error value for the EMD-BPNN, BPNN, SARIMA (1,1,2) (0,1,1)12 in 2018 is 7.80%, 10.79%, 9.48% respectively, and the mean absolute percentage error value for the ARIMA (3,1,0) model in 2017 and 2018 is 8.91%. CONCLUSIONS: The EMD-BPNN model was effective and reliable in predicting the incidence of HIV for annual incidence, and the results could furnish a scientific reference for policy makers and health agencies in Dalian.


Subject(s)
HIV Infections , China/epidemiology , Forecasting , HIV Infections/epidemiology , Humans , Incidence , Neural Networks, Computer
15.
Sensors (Basel) ; 22(5)2022 Mar 01.
Article in English | MEDLINE | ID: covidwho-1742607

ABSTRACT

This work addresses the challenge of building an accurate and generalizable periocular recognition model with a small number of learnable parameters. Deeper (larger) models are typically more capable of learning complex information. For this reason, knowledge distillation (kd) was previously proposed to carry this knowledge from a large model (teacher) into a small model (student). Conventional KD optimizes the student output to be similar to the teacher output (commonly classification output). In biometrics, comparison (verification) and storage operations are conducted on biometric templates, extracted from pre-classification layers. In this work, we propose a novel template-driven KD approach that optimizes the distillation process so that the student model learns to produce templates similar to those produced by the teacher model. We demonstrate our approach on intra- and cross-device periocular verification. Our results demonstrate the superiority of our proposed approach over a network trained without KD and networks trained with conventional (vanilla) KD. For example, the targeted small model achieved an equal error rate (EER) value of 22.2% on cross-device verification without KD. The same model achieved an EER of 21.9% with the conventional KD, and only 14.7% EER when using our proposed template-driven KD.


Subject(s)
Deep Learning , Biometry , Humans , Neural Networks, Computer
16.
Sensors (Basel) ; 22(5)2022 Feb 22.
Article in English | MEDLINE | ID: covidwho-1742604

ABSTRACT

The axle box in the bogie system of subway trains is a key component connecting primary damper and the axle. In order to extract deep features and large-scale fault features for rapid diagnosis, a novel fault reconstruction characteristics classification method based on deep residual network with a multi-scale stacked receptive field for rolling bearings of a subway train axle box is proposed. Firstly, multi-layer stacked convolutional kernels and methods to insert them into ultra-deep residual networks are developed. Then, the original vibration signals of four fault characteristics acquired are reconstructed with a Gramian angular summation field and trainable large-scale 2D time-series images are obtained. In the end, the experimental results show that ResNet-152-MSRF has a low complexity of network structure, less trainable parameters than general convolutional neural networks, and no significant increase in network parameters and calculation time after embedding multi-layer stacked convolutional kernels. Moreover, there is a significant improvement in accuracy compared to lower depths, and a slight improvement in accuracy compared to networks than unembedded multi-layer stacked convolutional kernels.


Subject(s)
Image Processing, Computer-Assisted , Neural Networks, Computer , Algorithms , Disease Progression , Humans , Image Processing, Computer-Assisted/methods
17.
Contrast Media Mol Imaging ; 2022: 7377502, 2022.
Article in English | MEDLINE | ID: covidwho-1741725

ABSTRACT

Coronavirus disease (COVID-19) is a viral infection caused by SARS-CoV-2. The modalities such as computed tomography (CT) have been successfully utilized for the early stage diagnosis of COVID-19 infected patients. Recently, many researchers have utilized deep learning models for the automated screening of COVID-19 suspected cases. An ensemble deep learning and Internet of Things (IoT) based framework is proposed for screening of COVID-19 suspected cases. Three well-known pretrained deep learning models are ensembled. The medical IoT devices are utilized to collect the CT scans, and automated diagnoses are performed on IoT servers. The proposed framework is compared with thirteen competitive models over a four-class dataset. Experimental results reveal that the proposed ensembled deep learning model yielded 98.98% accuracy. Moreover, the model outperforms all competitive models in terms of other performance metrics achieving 98.56% precision, 98.58% recall, 98.75% F-score, and 98.57% AUC. Therefore, the proposed framework can improve the acceleration of COVID-19 diagnosis.


Subject(s)
COVID-19 Testing , COVID-19/diagnostic imaging , Neural Networks, Computer , SARS-CoV-2 , Tomography, X-Ray Computed , Female , Humans , Male
18.
Sci Rep ; 12(1): 3930, 2022 03 10.
Article in English | MEDLINE | ID: covidwho-1740468

ABSTRACT

During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage healthcare resources. In this context, several experts have called for the necessity to account for human mobility to explain the spread of COVID-19. Existing approaches often apply standard models of the respective research field, frequently restricting modeling possibilities. For instance, most statistical or epidemiological models cannot directly incorporate unstructured data sources, including relational data that may encode human mobility. In contrast, machine learning approaches may yield better predictions by exploiting these data structures yet lack intuitive interpretability as they are often categorized as black-box models. We propose a combination of both research directions and present a multimodal learning framework that amalgamates statistical regression and machine learning models for predicting local COVID-19 cases in Germany. Results and implications: the novel approach introduced enables the use of a richer collection of data types, including mobility flows and colocation probabilities, and yields the lowest mean squared error scores throughout the observational period in the reported benchmark study. The results corroborate that during most of the observational period more dispersed meeting patterns and a lower percentage of people staying put are associated with higher infection rates. Moreover, the analysis underpins the necessity of including mobility data and showcases the flexibility and interpretability of the proposed approach.


Subject(s)
COVID-19/epidemiology , Neural Networks, Computer , Spatio-Temporal Analysis , Adolescent , Adult , Female , Germany/epidemiology , Humans , Machine Learning , Male , Middle Aged , Young Adult
19.
Comput Biol Med ; 144: 105344, 2022 May.
Article in English | MEDLINE | ID: covidwho-1734295

ABSTRACT

Many countries in the world have been facing the rapid spread of COVID-19 since February 2020. There is a dire need for efficient and cheap automated diagnosis systems that can reduce the pressure on healthcare systems. Extensive research is being done on the use of image classification for the detection of COVID-19 through X-ray and CT-scan images of patients. Deep learning has been the most popular technique for image classification during the last decade. However, the performance of deep learning-based methods heavily depends on the architecture of the deep neural network. Over the last few years, metaheuristics have gained popularity for optimizing the architecture of deep neural networks. Metaheuristics have been widely used to solve different complex non-linear optimization problems due to their flexibility, simplicity, and problem independence. This paper aims to study the different image classification techniques for chest images, including the applications of metaheuristics for optimization and feature selection of deep learning and machine learning models. The motivation of this study is to focus on applications of different types of metaheuristics for COVID-19 detection and to shed some light on future challenges in COVID-19 detection from medical images. The aim is to inspire researchers to focus their research on overlooked aspects of COVID-19 detection.


Subject(s)
COVID-19 , Deep Learning , Algorithms , COVID-19/diagnostic imaging , Humans , Neural Networks, Computer , SARS-CoV-2
20.
Comput Intell Neurosci ; 2022: 5115432, 2022.
Article in English | MEDLINE | ID: covidwho-1731354

ABSTRACT

In view of the impact of COVID-19 on the mental health of college students, this paper proposes a study on the relationship between psychological status and epidemic situation of university students based on BP neural network, so as to provide theoretical basis for universities to take targeted mental health education. This paper investigates the effects of COVID-19 on the psychological emotions of college students. According to the behavior and psychological characteristics of college students, the relevant investigation results are obtained through event monitoring, early warning, and usual performance, and a relationship model between college students' psychological status and epidemic situation based on BP neural network is constructed. This paper studies several factors through the relationship model and uses the principal component analysis method to analyze the impact of various factors on college students' psychology. According to the model prediction and result analysis, it concluded that the influence of COVID-19 should focus on improving the professional quality, physical quality, humanistic quality, and moral quality of university students, so as to improve the stability of colleges and universities in the event of public health emergencies. The model constructed in this paper can provide reference for carrying out mental health education and formulating effective intervention programs.


Subject(s)
COVID-19 , COVID-19/epidemiology , Humans , Neural Networks, Computer , SARS-CoV-2 , Students/psychology , Universities
SELECTION OF CITATIONS
SEARCH DETAIL