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Neuromuscul Disord ; 30(10): 859-861, 2020 10.
Article in English | MEDLINE | ID: covidwho-759207


In recent months, the new beta-coronavirus has caused a pandemic with symptoms affecting mainly the respiratory system. It is established that the virus may play a neurotropic role and in recent months several cases of Guillain-Barré-Strohl syndrome (GBS) have been reported in patients infected with COVID-19. We report the case of a 54-year-old patient with acute demyelinating polyneuropathy during infection by SARS-CoV-2 who progressed clinically to require assisted ventilation. After several weeks of specific symptomatic treatment, the patient had a favorable outcome. In conclusion, despite being a rare complication, we think it is important to consider the possibility of diffuse involvement of the peripheral nervous system in patients with COVID-19 to adjust clinical monitoring and treatment in these cases.

Betacoronavirus/pathogenicity , Coronavirus Infections/therapy , Coronavirus Infections/virology , Guillain-Barre Syndrome/therapy , Pneumonia, Viral/therapy , Pneumonia, Viral/virology , COVID-19 , Coronavirus Infections/complications , Coronavirus Infections/diagnosis , Guillain-Barre Syndrome/complications , Guillain-Barre Syndrome/diagnosis , Humans , Male , Middle Aged , Pandemics , Peripheral Nervous System/virology , Pneumonia, Viral/complications , Pneumonia, Viral/diagnosis , SARS-CoV-2
Indian J Med Res ; 152(1 & 2): 41-47, 2020.
Article in English | MEDLINE | ID: covidwho-732738


The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been predominantly a respiratory manifestation. Currently, with evolving literature, neurological signs are being increasingly recognized. Studies have reported that SARS-CoV-2 affects all aspects of the nervous system including the central nervous system (CNS), peripheral nervous system (PNS) and the muscular system as well. Not all patients have reverse transcription-polymerase chain reaction positive for the virus in the cerebrospinal fluid, and diagnosing the association of the virus with the myriad of neurological manifestations can be a challenge. It is important that clinicians have a high-index of suspicion for COVID-19 in patients presenting with new-onset neurological symptoms. This will lead to early diagnosis and specific management. Further studies are desired to unravel the varied neurological manifestations, treatment, outcome and long-term sequel in COVID-19 patients.

Central Nervous System/pathology , Coronavirus Infections/epidemiology , Nervous System Diseases/epidemiology , Peripheral Nervous System/pathology , Pneumonia, Viral/epidemiology , Betacoronavirus/pathogenicity , COVID-19 , Central Nervous System/virology , Coronavirus Infections/complications , Coronavirus Infections/pathology , Coronavirus Infections/virology , Humans , Muscle, Skeletal/pathology , Muscle, Skeletal/virology , Nervous System Diseases/complications , Nervous System Diseases/pathology , Nervous System Diseases/virology , Pandemics , Peripheral Nervous System/virology , Pneumonia, Viral/complications , Pneumonia, Viral/pathology , Pneumonia, Viral/virology , SARS-CoV-2