Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 84
Filter
2.
Ophthalmologica ; 245(4): 368-375, 2022.
Article in English | MEDLINE | ID: covidwho-1973979

ABSTRACT

INTRODUCTION: The aim was to identify changes in continuing education and training in ophthalmology in the context of the COVID-19 pandemic and advancing digitalization and to analyse the acceptance of e-learning tools among German ophthalmologists using a novel Retina Case App as an example. METHODS: The participants' training behaviour before and during the COVID-19 pandemic was surveyed. Furthermore, the acceptance and usability of the Retina Case App were evaluated using the System Usability Scale (SUS). A possible influence of the app on everyday clinical practice was assessed. RESULTS: A total of 145 ophthalmologists participated in the survey. The frequency of continuing medical education did not decrease for 62.8% of ophthalmologists during the pandemic. A significant increase in at least monthly use of online courses or lectures has been observed (90.3% vs. 28.2%, p < 0.001). No significant difference was identified in terms of frequency of use of print and digital journals or printed textbooks. The majority of participants stated that online training platforms are well suited to replace the absence of face-to-face events (73.8%). The mean SUS score was 87.7 (SD 11.9), which categorizes the app's usability as excellent. The majority agreed that the newly developed app enables faster learning (82.1%) and leads to increased motivation (71.7%). Most ophthalmologists (80.7%) felt that regular use of the app would improve confidence in the treatment of retinal diseases. CONCLUSIONS: The COVID-19 pandemic has led to a significant change in training behaviour in ophthalmology towards e-learning and online courses, which has not been accompanied by a general decline in training activity. The exemplarily investigated application showed a high user acceptance among ophthalmologists.


Subject(s)
COVID-19 , Computer-Assisted Instruction , Mobile Applications , Ophthalmologists , COVID-19/epidemiology , Humans , Pandemics , Retina
3.
Indian J Ophthalmol ; 70(4): 1412-1415, 2022 04.
Article in English | MEDLINE | ID: covidwho-1939179

ABSTRACT

The coagulation abnormalities and thromboembolic complications of coronavirus 2 (SARS-CoV-2) are now a well-established fact. The hypercoagulable state, the tendency for thromboembolism, and a cytokine surge state have been the exclusive reasons for multiorgan failure and other morbidities that have been regularly reported in COVID-19 patients. Ocular involvement in patients with active disease and those who have recovered is uncommon but not rare. We report a case series of four patients with CRVO, BRVO, CRAO, and vitreous hemorrhage in patients with proven COVID-19 infection and no other systemic ailments. The case series also tries to correlate the elevated D-dimer values, which signify a plausible prothrombotic state with the vaso-occlusive phenomenon in the retina leading to significant visual morbidity.


Subject(s)
COVID-19 , Retinal Vein Occlusion , COVID-19/complications , Humans , Retina , Retinal Vein Occlusion/complications , SARS-CoV-2
4.
Indian J Ophthalmol ; 70(4): 1140-1144, 2022 04.
Article in English | MEDLINE | ID: covidwho-1939166

ABSTRACT

Purpose: A deep learning system (DLS) using artificial intelligence (AI) is emerging as a very promising technology in the future of healthcare diagnostics. While the concept of telehealth is emerging in every field of medicine, AI assistance in diagnosis can become a great tool for successful screening in telemedicine and teleophthalmology. The aim of our study was to assess the acceptability of AI-based retina screening. Methods: This was a prospective non-randomized study performed in the outpatient department of a tertiary eye care hospital. Patients older than 18 years who came for a regular eye check-up or a routine retina screening were recruited in the study. Fundus images of the posterior pole were captured on fundus on a phone camera (REMIDIOTM, India) with a built-in AI software (Netra.AI) that can identify normal versus abnormal retina. The patients were then given an 8-point questionnaire to assess their acceptance and willingness toward AI-based screening. We recruited 104 participants. Results: We found that 90.4% were willing for an AI-based fundus screening; 96.2% were satisfied with AI-based screening. Patients with diabetes (P = 0.03) and the male population (P = 0.029) were more satisfied with the AI-based screening. The majority (i.e., 97.1%) felt that AI-based screening gave them a better understanding of their eye condition and 37.5% felt that AI-based retina screening prior to a doctor's visit can help in routine screening. Conclusion: Considering the current COVID-19 pandemic situation across the globe, this study highlights the importance of AI-based telescreening and positive patient approach toward this technology.


Subject(s)
COVID-19 , Ophthalmology , Telemedicine , Artificial Intelligence , COVID-19/epidemiology , Humans , Male , Pandemics , Prospective Studies , Retina
5.
Nat Commun ; 13(1): 513, 2022 01 26.
Article in English | MEDLINE | ID: covidwho-1915267

ABSTRACT

Loss of photoreceptors in atrophic age-related macular degeneration (AMD) results in severe visual impairment. Since the low-resolution peripheral vision is retained in such conditions, restoration of central vision should not jeopardize the surrounding healthy retina and allow for simultaneous use of the natural and prosthetic sight. This interim report, prespecified in the study protocol, presents the first clinical results with a photovoltaic substitute of the photoreceptors providing simultaneous use of the central prosthetic and peripheral natural vision in atrophic AMD. In this open-label single group feasibility trial (NCT03333954, recruitment completed), five patients with geographic atrophy have been implanted with a wireless 2 x 2 mm-wide 30 µm-thick device, having 378 pixels of 100 µm in size. All 5 patients achieved the primary outcome of the study by demonstrating the prosthetic visual perception in the former scotoma. The four patients with a subretinal placement of the chip demonstrated the secondary outcome: Landolt acuity of 1.17 ± 0.13 pixels, corresponding to the Snellen range of 20/460-20/565. With electronic magnification of up to a factor of 8, patients demonstrated prosthetic acuity in the range of 20/63-20/98. Under room lighting conditions, patients could simultaneously use prosthetic central vision and their remaining peripheral vision in the implanted eye and in the fellow eye.


Subject(s)
Electric Stimulation Therapy/instrumentation , Electric Stimulation Therapy/methods , Geographic Atrophy/therapy , Macular Degeneration/therapy , Vision Disorders/therapy , Visual Perception , Visual Prosthesis , Aged , Aged, 80 and over , Electric Stimulation , Equipment Design , Eyeglasses , Humans , Retina , Treatment Outcome , Visual Acuity
6.
Retin Cases Brief Rep ; 16(4): 403-406, 2022 Jul 01.
Article in English | MEDLINE | ID: covidwho-1909002

ABSTRACT

PURPOSE: To report a case of branch retinal artery occlusion associated with paracentral acute middle maculopathy on spectral-domain optical coherence tomography presumably related to heavy cannabis consumption. METHODS: Retrospective case report. Spectral-domain optical coherence tomography, fluorescein angiography, and optical coherence tomography angiography were performed. RESULTS: A 21-year-old healthy man described the acute onset of superior visual field loss in his right eye. He admitted smoking approximately 15 g daily of cannabis for several weeks during COVID-19 confinement. Ophthalmoscopic examination of the right eye showed inferotemporal retinal whitening. Spectral-domain optical coherence tomography illustrated evidence of the ischemic cascade with diffuse hyperreflectivity of the inner and middle retinal layers within the central region of the retinal infarct and paracentral acute middle maculopathy at the border of the infarct. Optical coherence tomography angiography demonstrated predominant flow signal loss at the level of the deep retinal capillary plexus. Fluorescein angiography and complete systemic workup were unremarkable. CONCLUSION: Branch retinal artery occlusion and paracentral acute middle maculopathy may be related to heavy cannabis use as the result of transient arterial vasospasm.


Subject(s)
COVID-19 , Cannabis , Macular Degeneration , Retinal Artery Occlusion , Retinal Diseases , Acute Disease , Adult , Cannabis/adverse effects , Fluorescein Angiography/methods , Humans , Infarction , Male , Retina , Retinal Artery Occlusion/chemically induced , Retinal Artery Occlusion/diagnosis , Retinal Diseases/chemically induced , Retinal Diseases/diagnosis , Retinal Vessels , Retrospective Studies , Tomography, Optical Coherence/methods , Young Adult
7.
Ophthalmic Surg Lasers Imaging Retina ; 53(6): 326-331, 2022 06.
Article in English | MEDLINE | ID: covidwho-1903576

ABSTRACT

BACKGROUND AND OBJECTIVE: The most common clinical features of X-linked retinoschisis (XLRS) include macular schisis in a spoke wheel pattern and peripheral schisis, though other findings such as vitreous veils, vascular attenuation, and subretinal fibrosis have been described. This is the first report to describe retinal folds as a characteristic feature in patients with XLRS. PATIENTS AND METHODS: This was a case series of patients presenting to the retina service at Bascom Palmer Eye Institute with genetically confirmed XLRS. Patients included in this report underwent examination under anesthesia with multimodality imaging. RESULTS: Three patients with XLRS were found to have retinal folds, including a newly characterized "retinal scroll" seen on examination and multimodality imaging. CONCLUSIONS: The presence of a retinal fold should yield a differential diagnosis that includes XLRS in the correct clinical context. Panel-based genetic testing and multimodal imaging are useful in guiding clinical management. [Ophthalmic Surg Lasers Imaging 2022;53(6):326-331.].


Subject(s)
Retinoschisis , Eye Proteins/genetics , Humans , Multimodal Imaging , Retina , Retinoschisis/diagnosis , Retinoschisis/genetics , Tomography, Optical Coherence/methods , Visual Acuity
8.
J Trop Pediatr ; 68(3)2022 04 05.
Article in English | MEDLINE | ID: covidwho-1853220

ABSTRACT

PURPOSE: Coronavirus disease 2019 (COVID-19) that is caused by severe acute respiratory syndrome coronavirus 2 can cause microvascular alterations that can lead to irreversible complications in multiple tissues and organs. Detrimental effects of COVID-19 on retinal structure have recently been reported in adult population. However, literature data about neonatal population is very scarce. Thus, we aimed to assess possible retinal changes of neonates recovered from COVID-19 infection in this prospective, observational, descriptive study. METHODS: The neonates recovered from COVID-19 infection were included to the study between 01 September 2020 and 30 April 2021. Their initial ophthalmological examination was made after a negative real-time reverse transcription-polymerase chain reaction obtained and all patients were re-examined 1 month later. All examinations were performed by same retina specialist using a binocular indirect ophthalmoscopy. RESULTS: A total of 15 neonates [9 (60%) male, 6 (40%) female, mean gestational age of 38.9 ± 0.9 weeks (ranging from 37 to 40 week)] were evaluated in the study. The mean age at the time of hospitalization was 17.5 ± 8.7 days (ranging from 2 to 29 days), and the mean duration of hospitalization was 12.5 ± 6.2 days (ranging from 4 to 27 days). Except for one patient with bilateral avascular area in Zone-III, no further retinal manifestation related to COVID-19 was found in the study. CONCLUSION: COVID-19 infection can cause retinal damage in neonates. Therefore, these patients should be closely monitored for signs of ocular involvement.


Subject(s)
COVID-19 , Adult , COVID-19/complications , COVID-19/diagnosis , Female , Hospitalization , Humans , Infant , Infant, Newborn , Male , Prospective Studies , Retina , SARS-CoV-2
9.
Immun Inflamm Dis ; 10(6): e619, 2022 06.
Article in English | MEDLINE | ID: covidwho-1850061

ABSTRACT

BACKGROUND: The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global pandemic in an unprecedented time frame. Systemic vascular involvement in COVID-19 has been identified, and SARS-CoV-2 has also been found to cause multiple organ ischemia and posterior ocular segment disease in mammals, raising concerns about the human retinal microvascular involvement in SARS-CoV-2. OBJECTIVE: To objectively assess the presence of retinal microvascular impairment in COVID-19 patients by optical coherence tomography angiography (OCTA), so as to facilitate the clinical system management of COVID-19 patients. METHODS: We searched PubMed, Cochrane Library, EMBASE, Ovid, CBM to collect eligible studies. The main outcomes included the vessel density (VD), area or perimeter of foveal avascular zone (FAZ), central foveal thickness (CFT), subfoveal choroidal thickness (SCT) in our meta-analysis. RESULTS: We eventually included five studies with a total of 401 participants. Our meta-analysis showed that nonacute infectious COVID-19 or post-COVID-19 patients presented significantly lower foveal VD of deep capillary plexus (WMD = -4.22, 95% CI [-8.00, -0.43]) and thinner SCT (WMD = -10.33, 95% CI [-19.08, -1.57]) than healthy controls. The foveal VD and parafoveal VD of superficial capillary plexus, parafoveal VD of deep capillary plexus, CFT, area, and perimeter of FAZ showed no significant differences between the groups. CONCLUSION: The patients of nonacute infectious COVID-19 or post-COVID-19 displayed alterations in the retinal microvasculature and choroidal vessels, including a significantly lower foveal VD in deep capillary plexus and thinner SCT. The impairment may be a medium to long-term process. Close ophthalmic surveillance is necessary for COVID-19 patients or post-COVID-19 patients.


Subject(s)
COVID-19 , Retinal Vessels , Fluorescein Angiography/methods , Humans , Retina/diagnostic imaging , Retinal Vessels/diagnostic imaging , SARS-CoV-2
10.
Ophthalmic Surg Lasers Imaging Retina ; 53(5): 246-248, 2022 05.
Article in English | MEDLINE | ID: covidwho-1847431

Subject(s)
COVID-19 , Humans , Retina , SARS-CoV-2
11.
Stem Cell Reports ; 17(4): 789-803, 2022 04 12.
Article in English | MEDLINE | ID: covidwho-1815188

ABSTRACT

Several studies have pointed to retinal involvement in COVID-19, yet many questions remain regarding the ability of SARS-CoV-2 to infect and replicate in retinal cells and its effects on the retina. Here, we have used human pluripotent stem cell-derived retinal organoids to study retinal infection by SARS-CoV-2. Indeed, SARS-CoV-2 can infect and replicate in retinal organoids, as it is shown to infect different retinal lineages, such as retinal ganglion cells and photoreceptors. SARS-CoV-2 infection of retinal organoids also induces the expression of several inflammatory genes, such as interleukin 33, a gene associated with acute COVID-19 and retinal degeneration. Finally, we show that the use of antibodies to block ACE2 significantly reduces SARS-CoV-2 infection of retinal organoids, indicating that SARS-CoV-2 infects retinal cells in an ACE2-dependent manner. These results suggest a retinal involvement in COVID-19 and emphasize the need to monitor retinal pathologies as potential sequelae of "long COVID."


Subject(s)
COVID-19 , Angiotensin-Converting Enzyme 2 , COVID-19/complications , Humans , Organoids/metabolism , Retina , Retinal Ganglion Cells , SARS-CoV-2
12.
Indian J Ophthalmol ; 70(2): 673-676, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1810682

ABSTRACT

A 41-year-old man presented to the emergency department complaining of decrease of vision in his left eye. Initial examination was consistent with retrobulbar optic neuritis, and an intravenous drip of methylprednisolone was started. On the third day, the fundus examination revealed the appearance of multiple Purtscher-like cotton-wool spots in the posterior pole and nasally to the optic disc, slight retinal whitening around the fovea, and cherry-red spot. The patient reported flu-like symptoms, and he tested positive at PCR (polymerase chain reaction) test for 2019-nCoV (2019 novel coronavirus) infection. Assuming possible 2019-nCoV-related vascular damage, we prescribed low-molecular-weight heparin. The lesions were regressing at follow-up, and we registered a complete visual recovery.


Subject(s)
COVID-19 , Retinal Diseases , Adult , Fundus Oculi , Humans , Male , Retina , SARS-CoV-2
13.
Curr Opin Pharmacol ; 64: 102231, 2022 06.
Article in English | MEDLINE | ID: covidwho-1797024

ABSTRACT

Coronavirus disease (COVID-19) outbreak has caused unprecedented global disruption since 2020. Approximately 238 million people are affected worldwide where the elderly succumb to mortality. Post-COVID syndrome and its side effects have popped up with several health hazards, such as macular degeneration and vision loss. It thus necessitates better medical care and management of our dietary practices. Natural flavonoids have been included in traditional medicine and have also been used safely against COVID-19 and several other diseases. Kaempferol is an essential flavonoid that has been demonstrated to influence several vital cellular signaling pathways involved in apoptosis, angiogenesis, inflammation, and autophagy. In this review, we emphasize the plausible regulatory effects of Kaempferol on hallmarks of COVID-19 and macular degeneration.


Subject(s)
COVID-19 , Macular Degeneration , Retinal Diseases , Aged , COVID-19/drug therapy , Flavonoids/therapeutic use , Humans , Kaempferols/pharmacology , Kaempferols/therapeutic use , Macular Degeneration/drug therapy , Macular Degeneration/metabolism , Retina/metabolism , Retinal Diseases/drug therapy
14.
Ophthalmol Retina ; 6(3): 254-255, 2022 03.
Article in English | MEDLINE | ID: covidwho-1747654

ABSTRACT

This prospective survey study demonstrates a lack of retina clinic patient knowledge about appropriate stem cell therapy applications for retinal disease.


Subject(s)
Retinal Diseases , Stem Cell Transplantation , Humans , Prospective Studies , Retina , Retinal Diseases/therapy
15.
Indian J Ophthalmol ; 69(11): 3297-3301, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1700007

ABSTRACT

PURPOSE: To study and compare the outcomes of pars plana vitrectomy (PPV) with the internal limiting membrane (ILM) peeling in the eyes with recalcitrant diabetic macular edema (DME) with and without vitreomacular traction. METHODS: A comparative prospective interventional study was undertaken in which group 1 included 45 eyes of 45 patients with DME with vitreomacular tractional component and group 2 included 45 eyes of 45 patients with recalcitrant DME without a tractional component. Both groups underwent standard PPV with ILM peeling. All the patients were followed up for a minimum of 6 months. The parameters evaluated were changes in the best-corrected visual acuity (BCVA), central macular thickness (CMT), multifocal electroretinogram (mfERG) parameters, and occurrence of any intraoperative/postoperative surgical complication. RESULTS: The mean CMT improved significantly from 540.6 and 490.2 µm at the baseline to 292.5 and 270.6 µm at 6 months in groups 1 and 2, respectively (P < 0.001). The mean BCVA logMAR improved from 0.78 ± 0.21 to 0.62 ± 0.22 in group 1 and 0.84 ± 0.19 to 0.65 ± 0.21 in group 2 at 6 months follow-up which was not statistically significant. The improvement in the mfERG was seen in group 2 as a significant increase in P1 wave amplitude in ring 2 (2-5°) (P < 0.004) and a significant decrease in P 1 wave implicit time in ring 1 (central 2°) (P < 0.001). None of the eyes suffered from the loss of BCVA or any major surgical complication in either group. CONCLUSION: PPV in recalcitrant DME provides good anatomical outcomes and the results are comparable in DME with and without a tractional component.


Subject(s)
Diabetes Mellitus , Diabetic Retinopathy , Epiretinal Membrane , Macular Edema , Basement Membrane/surgery , Diabetic Retinopathy/complications , Diabetic Retinopathy/diagnosis , Diabetic Retinopathy/surgery , Epiretinal Membrane/surgery , Humans , Macular Edema/diagnosis , Macular Edema/surgery , Prospective Studies , Retina , Retrospective Studies , Tomography, Optical Coherence , Traction , Visual Acuity , Vitrectomy
16.
Retina ; 42(4): 607-615, 2022 04 01.
Article in English | MEDLINE | ID: covidwho-1691767

ABSTRACT

PURPOSE: To characterize how community mobility patterns across the United States correlate with local changes in retina visits during the pandemic. METHODS: Outpatient retina clinic visits were linked to population mobility by combining multiple public data sets, including the Google Community Mobility Reports and data from the Centers for Disease Control and Infection. Percentage change from baseline in daily-average number of retina visits by county and mobility were measured by county. RESULTS: A total of 2,159,689 patient visits were examined across 332 counties. Daily-average retina visits decreased by 7.0%, 19.0%, 5.0%, and 4.0% from Quarter 1 to 4 of 2020. This decrease was negatively correlated with increased incident of COVID-19 deaths for Quarters 1 to 3 (r = -0.13, r = -0.16, and r = -0.15, respectively, P < 0.001) and increased incident cases for Quarters 1 and 2 (r = -0.18, r = -0.13, respectively, P < 0.001). Daily-average retina visits relative to baseline were significantly lower for metropolitan counties in Quarters 1 and 2, compared with urban and rural (P < 0.001). The decline in retina visits had greatest association with decline in workplace visits in Quarters 1 to 3 (r = 0.27, r = 0.09, r = 0.12, respectively, P < 0.001 for all). CONCLUSION: This study provides insight into how regional mobility patterns may help to explain and predict patient behaviors and retina outpatient visit responses during the COVID-19 pandemic.


Subject(s)
COVID-19 , Pandemics , COVID-19/epidemiology , Humans , Outpatients , Retina , Rural Population , United States/epidemiology
17.
BMC Surg ; 22(1): 41, 2022 Feb 05.
Article in English | MEDLINE | ID: covidwho-1690926

ABSTRACT

BACKGROUND: In concordance with medical recommendations in response to COVID-19, Emory Healthcare limited surgical procedures starting March 16, 2020. We investigated the impact of these recommendations on the number, types, and urgency of surgical retina cases. METHODS: We conducted a retrospective review of all surgical patients at the Retina division of the Emory Eye Center from February 17-April 12, 2020 and during the same time period in 2019 and 2018. The demographics of patients and the number, types and urgency of retina surgeries were collected. Descriptive statistics for each variable were reported. Univariate analysis was carried out using the chi-square test or Fisher's exact test for categorical covariates. RESULTS: From February 17-March 15 to March 16-April 12, 2020, total surgeries decreased from 87 to 34. Emergent cases, occurring within 7 days of surgical order placement, decreased from 23 to 18 (p = 0.0056), and urgent cases, occurring within 21 days of surgical order placement, decreased from 26 to 4 (p = 0.0380). From March 16-April 12, 2019 there were 62 surgeries: 21 emergent (34%), 14 urgent (23%). From March 16-April 12, 2018 there were 68 surgeries: 15 emergent (22%), 21 urgent (30%). After March 16, 2020, average patient age decreased from 39.4 to 25.7 years. There were no statistically significant differences in racial make-up or insurance coverage for those having surgery prior to versus after March 16, 2020. CONCLUSION: National recommendations for ophthalmologic surgeries during COVID-19 disproportionately affected older patients and patients with urgent cases at our tertiary care academic medical center. These results may inform the ophthalmologic field of the potential effects of pandemics such as COVID-19 on the surgical retina care of patients.


Subject(s)
COVID-19 , Humans , Pandemics , Retina , Retrospective Studies , SARS-CoV-2
18.
Photodiagnosis Photodyn Ther ; 38: 102742, 2022 Jun.
Article in English | MEDLINE | ID: covidwho-1661891

ABSTRACT

INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that is responsible for the current coronavirus disease pandemic and the vaccines currently developed are administered to prevent this infection. CoronaVac is a vaccine produced by the inactivated virus method. Ocular side effects such as anterior uveitis, optic neuritis, vision loss, episcleritis, allergic reaction and paracentral acute middle maculopathy have been reported after receiving CoronaVac vaccine. We assume that with this study, we can identify potential changes in posterior segment structures and posterior segment vascular density of people who received CoronaVac vaccine with optical coherence tomography angiography (OCTA) device. MATERIAL METHOD: Forty healthcare professionals who applied to the Health Sciences University Antalya Training and Research Hospital Ophthalmology Clinic for routine eye control were included in the study. The subjects who do not have any systemic condition and would be administered CoronaVac vaccine were chosen to assess. OCTA images of the patients before and within 1 week after vaccination were captured, then retinal and optic disc vascular values, foveal avascular zone (FAZ), choriocapillary blood flow (CBF), subfoveal choroidal thickness (SCT) and retinal thickness were analyzed and compared. RESULTS: Two of the 40 patients had burning and stinging in the eye (5%), two of the 40 patients had redness (5%) and itching (5%) in the eye. 36 patients did not have any ocular symptoms.No statistically significant difference was found in the retinal and optic disc vascular density values, FAZ, CBF, SCT and retinal thickness values ​​of the patients before and after vaccination. CONCLUSION: This is among the first studies in the literature to evaluate the changes in retinal and optic disc vascular values ​​in people who received CoronaVac vaccine. In this study, we observed that CoronaVac vaccine did not effect retinal and optic disc vascular density significantly.


Subject(s)
COVID-19 , Optic Disk , Photochemotherapy , Vaccines , COVID-19 Vaccines , Humans , Photochemotherapy/methods , Retina , SARS-CoV-2 , Tomography, Optical Coherence/methods
20.
Ophthalmic Surg Lasers Imaging Retina ; 52(S2): S17-S22, 2021 12.
Article in English | MEDLINE | ID: covidwho-1574804

ABSTRACT

Artificial intelligence (AI) applications are diverse and serve varied functions in clinical practice. The most successful products today are clinical decision tools used by physicians, but autonomous AI is gaining traction. Widespread use of AI is limited in part because of concerns about bias, fault-tolerance, and specificity. Adoption of AI often depends on removing cost and complexity in clinical workflow integration, providing clear incentives for use, and providing clear demonstration of clinical outcome. Existing wide-angle photographic screening could be integrated into the clinical workflow based on prior implementations for premature babies and linked with AI interpretation with existing technology. Incidence of retinal abnormality, clinical considerations, AI performance, grading variation for AI-augmented human grading, and cost and policy aspects play a significant role. Improved outcomes for newborns and a relatively high estimated incidence of abnormality have been named as benefits to counterweigh costs in the long term. [Ophthalmic Surg Lasers Imaging Retina. 2021;52:S17-S22.].


Subject(s)
Artificial Intelligence , Retina , Humans , Infant, Newborn , Neonatal Screening , Photography
SELECTION OF CITATIONS
SEARCH DETAIL