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J Eur Acad Dermatol Venereol ; 36(11): e868-e870, 2022 11.
Article in English | MEDLINE | ID: covidwho-1895997
Dermatol Ther ; 35(7): e15545, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1819890


The clinical presentation of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2 COVID-19) varies from asymptomatic infection to a life-threatening, multiorgan disease. One of these manifestations is telogen effluvium (TE) which is characterized by diffuse hair loss occurring in patients previously infected with SARS-CoV-2 and lasts ~3 months, after which excessive hair loss follows. Hair follicles are known to contain a well-characterized niche for adult stem cells which is the bulge containing epithelial and melanocytic stem cells. Stem cells in the hair bulge, a demarcated structure within the lower permanent portion of hair follicles, can generate the interfollicular epidermis, hair follicle structures, and sebaceous glands. This study aims to evaluate autologous micrografts from scalp tissues as a therapeutic modality in the management of TE caused by COVID-19. Twenty patients of previous COVID-19 infection suffered from TE were included in this study for human follicle stem cells micrograft scalp treatment and they were evaluated after 3 months of treatment and after 6 months. There was significant improvement of the hair thickness and density compared with the start of the treatment and 6 months of follow-up. Autologous micrograft of the scalp showed marked improvement in the treatment of COVID-19 TE.

Alopecia Areata , Autografts , COVID-19 , Hair Follicle , Microsurgery , Scalp , Adult , Alopecia Areata/etiology , Alopecia Areata/surgery , Alopecia Areata/virology , COVID-19/complications , COVID-19/virology , Follow-Up Studies , Hair Follicle/transplantation , Humans , SARS-CoV-2 , Scalp/transplantation , Stem Cell Transplantation , Time Factors
J Eur Acad Dermatol Venereol ; 36(6): 790-796, 2022 Jun.
Article in English | MEDLINE | ID: covidwho-1673165


Scalp dysesthesia is an abnormal sensation of the scalp in the absence of cutaneous disease. It is characterized by a burning and/or itching sensation and can be related to a variety of neurogenic or psychogenic causes. This condition is extremely bothersome and is also common- especially among the geriatric population, in women, in patients with diabetes mellitus, and patients with psychiatric history. However, despite its prevalence in many populations, there are limited data about its causes and characteristics. Given its limited cutaneous manifestations, it is also easily misdiagnosed and an underrecognized cause of scalp pruritus in the dermatological community. Therefore, education on scalp dysesthesia is paramount to helping physicians identify and provide appropriate treatment for these patients. This review focuses predominantly on the neurogenic causes (with a brief review of psychogenic itch) of scalp dysesthesia and the therapeutics that have been found to be effective for this condition. Neurogenic causes of scalp dysesthesia occur with damage to the central or peripheral pathways of itch sensation, resulting in modification and heightened sensitivity of nerves that result in abnormal sensations in the absence of or out of proportion to external stimuli. A comprehensive review of etiologies is provided here, ranging from lesions to the central nervous system caused by cervical spine disease, trigeminal trophic syndrome, tumor, stroke, and multiple sclerosis, to small-fiber neuropathies caused by diabetes, brow lifts, keloid, and burn scarring. Recently, there have also been reports of scalp dysesthesias associated with post-infectious COVID-19. Treatment options tailored toward disease severity and different causes of disease will also be discussed. By elucidating the different mechanisms and therapeutic treatments of scalp dysesthesia, we hope to provide clinicians with the tools to identify and treat this condition as well as encourage further research into its etiologies and therapeutics.

COVID-19 , Skin Diseases , Aged , Female , Humans , Paresthesia/etiology , Pruritus/etiology , Scalp , Skin Diseases/complications
BMJ Case Rep ; 14(2)2021 Feb 05.
Article in English | MEDLINE | ID: covidwho-1066846


A young man presented to our centre needing an urgent debridement of his postcraniotomy wound due to massive myiasis during the COVID-19 pandemic in October 2020. Prior to the surgery, his nasopharyngeal swab real-time PCR test result was unknown. One day later, it returned as SARS-CoV-2 positive. All healthcare workers who were involved in the patient management avoided cross infection as they wore appropriate personal protective equipment. This article depicts the importance of adequate preparations when handling potentially infectious patients and the perioperative issues associated with it.

COVID-19/complications , Debridement/methods , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Myiasis/complications , Myiasis/surgery , Perioperative Care/methods , Scalp/surgery , Adult , COVID-19/prevention & control , Humans , Male , Personal Protective Equipment , SARS-CoV-2 , Young Adult
Int J Dermatol ; 60(5): e195-e197, 2021 May.
Article in English | MEDLINE | ID: covidwho-1057996

COVID-19 , SARS-CoV-2 , Alopecia , Humans , Scalp
J Am Acad Dermatol ; 84(2): e87-e88, 2021 02.
Article in English | MEDLINE | ID: covidwho-988142
Pediatr Dermatol ; 37(6): 1193-1194, 2020 Nov.
Article in English | MEDLINE | ID: covidwho-744798


Within a two-week timespan in April 2020, multiple children presented with hemorrhagic macules, papules, and erosions localized to the posterior neck and occipital scalp. All of these patients were children of health care workers, with at least one confirmed COVID-19 exposure. The unique lesional morphology and the timing of onset led to SARS-CoV-2 antibody testing for all and biopsy of one child. Biopsy ultimately confirmed these lesions were consistent with arthropod bites, which coincided with an unprecedented surge in local populations of Simulium tuberosum, a biting gnat.

Bites and Stings/diagnosis , Disease Outbreaks , Neck , Scalp , Simuliidae , Animals , Biopsy , COVID-19/diagnosis , Child, Preschool , Diagnosis, Differential , Female , Humans , Male , Minnesota , Pandemics
J Neurosurg Anesthesiol ; 34(1): e73, 2022 01 01.
Article in English | MEDLINE | ID: covidwho-744588