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1.
Acta Otorhinolaryngol Ital ; 42(Suppl. 1): S87-S93, 2022 Apr.
Article in English | MEDLINE | ID: covidwho-1863394

ABSTRACT

Objective: The persistence of auditory, vestibular, olfactory, and gustatory dysfunction for an extended time after COVID-19 has been documented, which represents an emerging challenge of which ENT specialists must be aware. This systematic review aims to evaluate the prevalence of persistent audiovestibolar and olfactory/gustatory symptoms in patients with "long-COVID". Methods: The literature was systematically reviewed according to PRISMA guidelines; PubMed, Scopus and Google Scholar were screened by searching articles on audiovestibular symptoms and olfactory/gustatory dysfunction after SARS-CoV-2 infection. The keywords used were hearing loss, tinnitus, vertigo, smell disorders, parosmia, anosmia, hyposmia, dysgeusia combined with COVID-19 or SARS-CoV-2. Results: 1100 articles were identified. After removal of duplicates (382), 702 articles were excluded, and 16 were included in the systematic review. All articles included identified an association between SARS-CoV-2 infection and persistent hearing or chemosensory impairment. The studies were published over a period of 2 years, between 2019 and 2021. Conclusions: The likelihood of patients with persistent audiovestibular symptoms related to COVID-19 was different among the articles; however, olfactory and gustatory disturbances were more consistently reported. Studies with longer follow-up are required to fully evaluate the long-term impact of these conditions.


Subject(s)
COVID-19 , Olfaction Disorders , Taste Disorders , COVID-19/complications , Hearing Disorders/diagnosis , Hearing Disorders/virology , Humans , Olfaction Disorders/diagnosis , Olfaction Disorders/virology , SARS-CoV-2 , Taste Disorders/diagnosis , Taste Disorders/virology , Vertigo/diagnosis , Vertigo/virology
3.
Int J Audiol ; 59(7): 487-491, 2020 07.
Article in English | MEDLINE | ID: covidwho-596122

ABSTRACT

Objective: This rapid systematic review investigated audio-vestibular symptoms associated with coronavirus.Design: The protocol for the rapid review was registered in the International Prospective Register of Systematic Reviews and the review methods were developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Risk of bias was assessed using the National Institute of Heath quality assessment tools.Study sample: After rejecting more than 2300 records, there were five case reports and two cross-sectional studies that met the inclusion criteria.Results: No records of audio-vestibular symptoms were reported with the earlier types of coronavirus (i.e. severe acute respiratory syndrome [SARS] and Middle East respiratory syndrome [MERS]). Reports of hearing loss, tinnitus, and vertigo have rarely been reported in individuals who tested positive for the SARS-CoV-2.Conclusion: Reports of audio-vestibular symptoms in confirmed COVID-19 cases are few, with mostly minor symptoms, and the studies are of poor quality. Emphasis over time is likely to shift from life-threatening concerns to longer-term health-related consequences such as audio-vestibular dysfunction. High-quality studies are needed to investigate the acute effects of COVID-19, as well as for understanding long-term risks, on the audio-vestibular system. Review registration: Prospective Register of Systematic Reviews (PROSPERO; registration number CRD42020184932).


Subject(s)
Betacoronavirus , Coronavirus Infections/complications , Hearing Disorders/virology , Pneumonia, Viral/complications , Vestibular Diseases/virology , COVID-19 , Coronavirus Infections/virology , Humans , Pandemics , Pneumonia, Viral/virology , SARS-CoV-2 , Tinnitus/virology , Vertigo/virology
5.
Clin Nucl Med ; 45(6): 495-496, 2020 Jun.
Article in English | MEDLINE | ID: covidwho-120660

ABSTRACT

Neurological symptoms and gastrointestinal symptoms were rare at onset in COVID-19. Here we report a 37-year-old man with vertigo, fever, and diarrhea symptoms as the first manifestation. F-FDG PET/CT spotted multiple ground glass opacity (GGO) lesions in the lungs, with increased tracer uptake in both lung GGOs and the whole colon. Serial CT examinations showed the emersion and dissipation of lung GGOs. We illustrate the symptoms initiation, the laboratory test results, the imaging examination, and the treatment strategy in the duration of COVID-19 with a timeline chart.


Subject(s)
Coronavirus Infections/diagnostic imaging , Pneumonia, Viral/diagnostic imaging , Positron Emission Tomography Computed Tomography , Adult , Betacoronavirus , COVID-19 , Diarrhea/virology , Fever/virology , Fluorodeoxyglucose F18 , Humans , Lung/diagnostic imaging , Lung/pathology , Male , Pandemics , SARS-CoV-2 , Vertigo/virology
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