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1.
Front Neurol ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32425880

ABSTRACT

COVID-19 has rapidly become a pandemic emergency, distressing health systems in each affected country COVID-19 determines the need for healthcare in a large number of people in an extremely short time and, like a tsunami wave, overruns emergency, infectious diseases, and pneumology departments as well as intensive care units, choking healthcare services Rehabilitation services are also affected by this epidemic which forces radical changes both in the organization and in the operating methods In the absence of reference literature on this issue, this report aims to provide a background documentation to support physicians and healthcare personnel involved in neurorehabilitation and rehabilitation care

2.
Front Public Health ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32426318

ABSTRACT

As the coronavirus outbreak quickly surges worldwide, many countries are adopting non-therapeutic preventive measures, which include travel bans, remote office activities, country lockdown, and most importantly, social distancing However, these measures face challenges in Bangladesh, a lower-middle-income economy with one of the world's densest populations Social distancing is difficult in many areas of the country, and with the minimal resources the country has, it would be extremely challenging to implement the mitigation measures Mobile sanitization facilities and temporary quarantine sites and healthcare facilities could help mitigate the impact of the pandemic at a local level A prompt, supportive, and empathic collaboration between the Government, citizens, and health experts, along with international assistance, can enable the country to minimize the impact of the pandemic

3.
Front Med (Lausanne) ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32426363

ABSTRACT

The new coronavirus SARS-CoV-2 pandemic of early 2020 poses an enormous challenge to global public health Coronavirus Disease 2019 (COVID-19) caused by the virus has spread rapidly throughout the world, taking thousands of lives in just over 2 months It is critical to refine the incidence and mortality risks of COVID-19 for the effective management of the general public and patients during the outbreak In this report, we investigate the incidence and mortality risks of the infection by analyzing the age composition of 5,319 infected patients, 76 fatal cases, and 1,144,648 individuals of the general public in China Our results show a relatively low incidence risk for young people but a very high mortality risk for seniors Notably, mortality risk could be as high as 0 48 for people older than 80 years Furthermore, our study suggests that a good medical service can effectively reduce the mortality rate of the viral infection to 1% or less

4.
Front Cardiovasc Med ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32426374

ABSTRACT

In December 2019, Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2, occurred in China and has currently led to a global pandemic In addition to respiratory involvement, COVID-19 was also associated with significant multiple organ dysfunction syndrome (MODS) Cardiovascular impairment has been observed and is now drawing growing attention Cardiovascular protective strategies are urgent and of great significance to the overall prognosis of COVID-19 patients Direct viral infection, cytokine storm, and aggravation of existing cardiovascular diseases were recognized as possible mechanisms of cardiovascular impairment in COVID-19 Hyperactivated inflammation plays an important role in all three mechanisms and is considered to be fundamental in the development of cardiovascular impairment and MODS in COVID-19 Therefore, in addition to conventional cardiovascular treatment, anti-inflammatory therapy is a reasonable strategy for severe cases to further enhance cardiovascular protection and potentially mitigate MODS We reviewed the inflammatory features and current promising treatments of COVID-19 as well as cardiovascular anti-inflammatory therapies that have been verified in previous clinical trials with positive outcomes We believe that targeting the central pathway (IL-1beta, TNF-alpha, IL-6), balancing the Th1 and Th2 response, and administering long-term anti-inflammatory therapy might be promising prospects to reduce cardiovascular impairment and even MODS during the acute and recovery phases of COVID-19 The cardiovascular anti-inflammatory therapies might be of great application value to the management of COVID-19 patients and we further propose an algorithm for the selection of anti-inflammatory therapy for COVID-19 patients with or at high risk of cardiovascular impairment We recommend to take the experiences in cardiovascular anti-inflammatory therapy as references in the management of COVID-19 and conduct related clinical trials, while the clinical translation of novel treatments from preclinical studies or in vitro drug screening should proceed with caution due to unguaranteed efficacy and safety profiles

5.
Clin Pract Cases Emerg Med ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32426653

ABSTRACT

Introduction: Coronavirus disease 2019 (COVID-19) is caused by the virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Several case series from Italy and China have highlighted the lung ultrasound findings of this disease process and may demonstrate its clinical utility during the current pandemic Case Report: We present a case of a COVID-19 patient who presented to the emergency department twice within a 24-hour period with rapidly progressing illness A multi-organ point-of-care ultrasound (POCUS) evaluation was used on the return visit and assisted clinical decision-making Discussion: A multi-organ POCUS exam allows for quick assessment of acute dyspnea in the emergency department As the lung involvement of COVID-19 is primarily a peripheral process it is readily identifiable via lung ultrasound We believe that when applied efficiently and safely a POCUS exam can reduce clinical uncertainty and potentially limit the use of other imaging modalities when treating patients with COVID-19 Conclusion: This case highlights the utility of an early multiorgan point-of-care assessment for patients presenting with moderate respiratory distress during the severe SARS-CoV-2 pandemic

6.
Crit Care Explor ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32426755

ABSTRACT

Social distancing as a technique to limit transmission of infectious disease has come into common parlance following the arrival and rapid spread of a novel coronavirus disease around the world in 2019 and 2020 But in the face of an emerging pandemic threat, it is crucial that we start to apply these principles to the clinic, the emergency department, and the hospital ward We propose that this dynamic situation calls for a parallel "Clinical Distancing" in which we as a medical culture go against many of our fundamental instincts and, at least in the short term, begin to reduce unnecessary patient-care contacts for the benefit of our patients and our ability to continue to provide care to those who need it most In this commentary, we provide specific recommendations for the rapid implementation of clinical distancing techniques

7.
OMICS ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427517

ABSTRACT

The successful sequencing of the novel coronavirus SARS-CoV-2 nucleic acid paved the way for exploration of omics systems science and integrative biology research approaches for combating this unprecedented planetary health challenge Omics-scale studies on this viral infection are emerging rapidly and offer a tremendous potential to unravel the puzzles of the SARS-CoV-2 pathobiology, and ways forward for diagnostic and therapeutic innovation

8.
Orv Hetil ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427569

ABSTRACT

The first Hungarian COVID-19 case was reported on March 4, 2020 by Hungarian officials Healthcare workers (HCWs) are at the highest risk of contracting the novel coronavirus (SARS-CoV-2), with 12% of total coronavirus cases confirmed among them recently 80% of the infected persons show only mild, moderate symptoms or stay asymptomatic The single-stranded viral RNA can be detected by RT-PCR from the respiratory tract, urine, blood and, particulary in children, from stool samples for 30-40 days We have no valid data of how many HCWs have been infected since the Hungarian SARS-CoV-2 outbreak, due to the lack of the systematic screening HCWs could play a critical role in transmission and might jeopardize the health of both their patients and their own family members Both cross-sectional and longitudinal sudies are recommended to evaluate the ratio of the recovered, i e , "already protected", the ones in the acute phase, i e , "the infectious", and the virus-naive, i e , "at risk" workers Of the available molecular diagnostic options, in addition to RT-PCR it would be advisable to introduce the novel rapid antibody tests which can give quick results, reveal the timeline of the infection, are easy to handle, inexpensive and can be used periodically to monitor HCWs' viral status during the still unkown duration of the SARS-CoV-2 pandemic Orv Hetil 2020;161(21): 854-860

10.
Acad Med ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427597
11.
Acad Med ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427598
12.
Crit Care Med ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427614
13.
Curr Opin Urol ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427632

ABSTRACT

PURPOSE OF REVIEW: The novel coronavirus-2019 disease (COVID-19) pandemic has had devastating consequences on healthcare systems globally The effect this has on urologists and the patients they care for is not fully understood and presents the challenge of prioritizing the most urgent cases We aim to review the impact on urology services and evaluate strategies to minimize disruption RECENT FINDINGS: Various healthcare systems have been forced to postpone treatment for many urological conditions as resources are dedicated to the treatment of COVID-19 Training has been postponed as staff are reallocated to areas of need Face-to-face contact is largely minimized and innovative, virtual communication methods are used in the outpatient setting and multidisciplinary team meetings Surgical practice is changing because of the risks posed by COVID-19 and procedures can be prioritized in a nonurgent, low priority, high priority or emergency category SUMMARY: Although the COVID-19 pandemic will inevitably affect urological services, steps can be taken to mitigate the impact and prioritize the patients most in need of urgent care Similarly, in future;simulation, e-learning and webinars will allow interaction to share, discuss and debate focused training and education

14.
Cardiol Rev ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427637

ABSTRACT

The COVID-19 pandemic has placed a significant strain on healthcare providers As the number of patients continue to surge, healthcare workers are now forced to find different approaches to practicing medicine that may affect patient care In addition, COVID-19 has many cardiovascular complications that affect the clinical course of patients In this article we summarize the cardiovascular impact of COVID-19 and some of the challenges that patients and the healthcare system will face during this pandemic

19.
Rehabil Nurs ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427685
20.
J Bone Joint Surg Am ; 2020.
Article | COVIDWHO | ID: covidwhomdl-32427767
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