QBB rapid transformation into COVID-19 Biorepository: A showcase

ABSTRACT

Background: The SARS-CoV-2 virus and the outbreak of COVID-19 disease has been one of the most important global crises on public health. Qatar Biobank (QBB) had to convert and respond to this crisis by providing its services for the collection, processing and storage of high-quality data and specimens for the better understanding and the response to the therapy and survival of COVID-19 disease. In this study we will highlight the challenges, risks and opportunities of QBB during this transformation period. Methods: QBB is CAP accredited and holds ISO certification for Quality Management Systems 90012105 and Information Security Management Systems 27001 2013. These standards helped QBB management to rabidly adapt by following rigorous processes to effectively convert its operations and facilitate the COVID-19 National project. Results: Within 5 weeks QBB transformed to accommodate a disease/virus-based biorepository. Multi-adjustments had to be implemented at operational level such as i) QBB IT department developed a highly secured electronic system for the data collection and specimen traceability ii) Clinically trained staff (n = 17) were transferred to different healthcare facilities in order to recruit COVID-19 positive patients;iii) QBB Laboratory designed special collection kit, iv) QBB Medical Review Office (n = 4) and Scientific and Education (n = 2) departments managed the recruitment process, set up the study and provided training to the staff;v) the Communications and Participants Recruitment Department (n = 7) transformed its operations to fit the needs of the COVID-19 initiative. The Research Access Office (n = 6) designed the COVID-19 access portal and supported the project from the purchasing of PPE and other administrative works needed. Conclusion: It is now time to consider lessons learned, as many countries have been affected by COVID-19 outbreak, and to understand that biobanks are an asset for a country and integrate them into a new standard with their sustainability in mind. Qatar Biobank and its network with academic, research and governmental entities is a good showcase.