Clinical efficacy and safety profile of hydroxychloroquine and azithromycin against COVID-19.

Gautret, Philippe; Lagier, Jean-Christophe; Honoré, Stéphane; Hoang, Van Thuan; Raoult, Didier

Gautret, Philippe; Lagier, Jean-Christophe; Honoré, Stéphane; Hoang, Van Thuan; Raoult, Didier.

Gautret P; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.
Lagier JC; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.
Honoré S; Service Pharmacie, Hôpital Timone, AP-HM, Marseille, France; Laboratoire de Pharmacie Clinique, Aix Marseille Université, Marseille, France.
Hoang VT; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France; Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam.
Raoult D; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France. Electronic address: Didier.raoult@gmail.com.

Int J Antimicrob Agents ; 57(1): 106242, 2021 Jan.

Article in English | MEDLINE | ID: covidwho-1065139

Subject(s)

Antiviral Agents/therapeutic use; Azithromycin/therapeutic use; COVID-19 Drug Treatment; Hydroxychloroquine/therapeutic use; SARS-CoV-2/drug effects; Anti-Bacterial Agents/therapeutic use; Antimalarials/therapeutic use; COVID-19/virology; Clinical Trials as Topic; Drug Combinations; Drug Interactions; Drug Repositioning; Drug Synergism; Electrocardiography; Humans; Hyperkalemia/prevention & control; Hypokalemia/prevention & control; Long QT Syndrome/prevention & control; Magnesium/administration & dosage; Patient Safety; RNA, Viral/antagonists & inhibitors; RNA, Viral/genetics; SARS-CoV-2/genetics; SARS-CoV-2/pathogenicity; Treatment Outcome

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Azithromycin / SARS-CoV-2 / COVID-19 Drug Treatment / Hydroxychloroquine Type of study: Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Int J Antimicrob Agents Year: 2021 Document Type: Article Affiliation country: J.ijantimicag.2020.106242

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