Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Codon Usage and Replicative Fitness.
Glob Med Genet
; 7(3): 92-94, 2020 Oct.
Article
in English
| MEDLINE | ID: covidwho-1005856
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) codon usage, as shown by the polyprotein coding sequence, shows better translation potential in the human host when compared with human coronavirus OC43 (HCoV-OC43) codon usage. Such translational advantage might facilitate SARS-CoV-2 replication, immunogenicity, and pathogenicity, thus also accounting for the less harmful character of HCoV-OC43 infection.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Language:
English
Journal:
Glob Med Genet
Year:
2020
Document Type:
Article
Affiliation country:
S-0040-1721080
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