COVID-19 - A vascular disease.

Siddiqi, Hasan K; Libby, Peter; Ridker, Paul M

Siddiqi, Hasan K; Libby, Peter; Ridker, Paul M.

Siddiqi HK; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Libby P; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: plibby@bwh.harvard.edu.
Ridker PM; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

Trends Cardiovasc Med ; 31(1): 1-5, 2021 01.

Article in English | MEDLINE | ID: covidwho-1006309

ABSTRACT

ABSTRACT

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to multi-system dysfunction with emerging evidence suggesting that SARS-CoV-2-mediated endothelial injury is an important effector of the virus. Potential therapies that address vascular system dysfunction and its sequelae may have an important role in treating SARS-CoV-2 infection and its long-lasting effects.

Subject(s)

COVID-19/complications; COVID-19/therapy; SARS-CoV-2/pathogenicity; Vascular Diseases/therapy; Vascular Diseases/virology; Endothelium, Vascular/metabolism; Endothelium, Vascular/pathology; Endothelium, Vascular/physiopathology; Humans

Keywords

Coagulation; Endothelium; Inflammation; Microvessels; Thrombosis

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vascular Diseases / SARS-CoV-2 / COVID-19 Topics: Long Covid Limits: Humans Language: English Journal: Trends Cardiovasc Med Journal subject: Vascular Diseases / Cardiology Year: 2021 Document Type: Article Affiliation country: J.tcm.2020.10.005

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