SARS-COV2 Alters Blood Brain Barrier Integrity Contributing to Neuro-Inflammation.

Reynolds, Jessica L; Mahajan, Supriya D

Reynolds, Jessica L; Mahajan, Supriya D.

Reynolds JL; Department of Medicine, Division of Allergy, Immunology & Rheumatology, Jacobs School of Medicine and Biomedical Sciences, Clinical & Translational Research Center, University at Buffalo, 875 Ellicott Street, Buffalo, NY, 14203, USA.
Mahajan SD; Department of Medicine, Division of Allergy, Immunology & Rheumatology, Jacobs School of Medicine and Biomedical Sciences, Clinical & Translational Research Center, University at Buffalo, 875 Ellicott Street, Buffalo, NY, 14203, USA. smahajan@buffalo.edu.

J Neuroimmune Pharmacol ; 16(1): 4-6, 2021 03.

Article in English | MEDLINE | ID: covidwho-1009182

Subject(s)

Blood-Brain Barrier; COVID-19/physiopathology; Encephalitis, Viral/physiopathology; SARS-CoV-2/pathogenicity; Angiotensin-Converting Enzyme 2/physiology; Astrocytes/drug effects; Astrocytes/metabolism; Astrocytes/virology; Brain/blood supply; COVID-19/complications; Cell Line; Culture Media, Conditioned/pharmacology; Cytokine Release Syndrome/etiology; Cytokines/biosynthesis; Cytokines/genetics; Encephalitis, Viral/etiology; Encephalitis, Viral/virology; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Endothelial Cells/virology; Gene Expression Regulation, Viral; Humans; Microvessels/virology; Oxidative Stress; Receptors, Virus/physiology; SARS-CoV-2/physiology; Spike Glycoprotein, Coronavirus/pharmacology; Spike Glycoprotein, Coronavirus/physiology; Tight Junction Proteins/biosynthesis; Tight Junction Proteins/genetics

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Blood-Brain Barrier / Encephalitis, Viral / SARS-CoV-2 / COVID-19 Topics: Long Covid Limits: Humans Language: English Journal: J Neuroimmune Pharmacol Journal subject: Allergy and Immunology / Pharmacology / Neurology Year: 2021 Document Type: Article Affiliation country: S11481-020-09975-y

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