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The Impact of Peripheral Eosinophil Counts and Eosinophil to Lymphocyte Ratio (ELR) in the Clinical Course of COVID-19 Patients: A Retrospective Study.
Georgakopoulou, Vasiliki E; Garmpis, Nikolaos; Damaskos, Christos; Valsami, Serena; Dimitroulis, Dimitrios; Diamantis, Evangelos; Farmaki, Paraskevi; Papageorgiou, Chrysovalantis V; Makrodimitri, Sotiria; Gravvanis, Nikolaos; Velonias, Stamatis; Sklapani, Pagona; Trakas, Nikolaos; Antoniou, Efstathios A; Kontzoglou, Konstantinos; Nikolidakis, Lampros; Damaskou, Zoi; Syllaios, Athanasios; Marinos, Georgios; Vogiatzi, Georgia; Korrou, Georgia-Eleni; Kyriakos, Georgios; Quiles-Sanchez, Lourdes-Victoria; Patsouras, Alexandros; Lamprinos, Dimitrios; Stelianidi, Athanasia; Savvanis, Spyridon; Garmpi, Anna.
  • Georgakopoulou VE; Department of Pulmonology, Laiko General Hospital, Athens, Greece.
  • Garmpis N; First Department of Pulmonology, Sismanogleio Hospital, Athens, Greece.
  • Damaskos C; Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Valsami S; N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Dimitroulis D; N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece; x_damaskos@yahoo.gr.
  • Diamantis E; Renal Transplantation Unit, Laiko General Hospital, Athens, Greece.
  • Farmaki P; Blood Transfusion Department, Aretaieion Hospital, Medical School, National and Kapodistrian Athens University, Athens, Greece.
  • Papageorgiou CV; Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Makrodimitri S; Department of Endocrinology and Diabetes Center, G. Gennimatas General Hospital, Athens, Greece.
  • Gravvanis N; First Department of Pediatrics, Agia Sofia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Velonias S; Department of Pulmonology, Laiko General Hospital, Athens, Greece.
  • Sklapani P; Department of Pulmonology, Laiko General Hospital, Athens, Greece.
  • Trakas N; Health Center Peristeriou, Peristeri, Greece.
  • Antoniou EA; Health Center Peristeriou, Peristeri, Greece.
  • Kontzoglou K; Department of Cytology, Mitera-Hygeia Hospital, Athens, Greece.
  • Nikolidakis L; Biochemistry Department, Sismanogleio Hospital, Athens, Greece.
  • Damaskou Z; Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Syllaios A; N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Marinos G; Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Vogiatzi G; N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Korrou GE; Department of Internal Medicine, Ygeias Melathron Hospital, Athens, Greece.
  • Kyriakos G; Department of Internal Medicine, Ygeias Melathron Hospital, Athens, Greece.
  • Quiles-Sanchez LV; First Department of Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Patsouras A; Emergency Department, Laiko General Hospital, Athens, Greece.
  • Lamprinos D; Emergency Department, Laiko General Hospital, Athens, Greece.
  • Stelianidi A; Emergency Department, Laiko General Hospital, Athens, Greece.
  • Savvanis S; Seccion de Endocrinologia y Nutrition, Hospital General Universitario Santa Lucia, Cartagena, Spain.
  • Garmpi A; Centro de Salud Jesús Marín, Murcia, Spain.
In Vivo ; 35(1): 641-648, 2021.
Article in English | MEDLINE | ID: covidwho-1011857
ABSTRACT
BACKGROUND/

AIM:

Eosinophils are blood cells responsible for response against parasites and allergens. Eosinophil to lymphocyte ratio (ELR) is a biomarker for inflammatory conditions. Our aim was to evaluate the role of eosinophils and ELR in COVID-19 patients. PATIENTS AND

METHODS:

The study included 96 patients hospitalized with COVID-19. They were classified into moderate to severe cases and critical cases. Eosinophils and ELR were determined in both groups, in patients that died or survived and were correlated to duration of hospitalization.

RESULTS:

There was a statistically significant decrease in eosinophils and ELR between patients that died and patients that survived (p<0.05), and in mean values of the two biomarkers (p<0.05 for eosinophils and p<0.05 for ELR) between patients hospitalized for more or less than 15 days among those with moderate to severe disease.

CONCLUSION:

Lower eosinophil counts and ERL could probably predict worse outcome in COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lymphocytes / Eosinophils / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: In Vivo Journal subject: Neoplasms Year: 2021 Document Type: Article Affiliation country: Invivo.12303

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Lymphocytes / Eosinophils / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: In Vivo Journal subject: Neoplasms Year: 2021 Document Type: Article Affiliation country: Invivo.12303