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Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections' Collaborative of the European Society of Pediatric and Neonatal Intensive Care.
Rimensberger, Peter C; Kneyber, Martin C J; Deep, Akash; Bansal, Mehak; Hoskote, Aparna; Javouhey, Etienne; Jourdain, Gilles; Latten, Lynne; MacLaren, Graeme; Morin, Luc; Pons-Odena, Marti; Ricci, Zaccaria; Singh, Yogen; Schlapbach, Luregn J; Scholefield, Barnaby R; Terheggen, Ulrich; Tissières, Pierre; Tume, Lyvonne N; Verbruggen, Sascha; Brierley, Joe.
  • Rimensberger PC; Division of Neonatology and Paediatric Intensive Care, Department of Paediatrics, University Hospital of Geneva, University of Geneva, Geneva, Switzerland.
  • Kneyber MCJ; Division of Paediatric Critical Care Medicine, Department of Paediatrics, Beatrix Children's Hospital, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
  • Deep A; Critical Care, Department of Anaesthesiology, Peri-operative & Emergency Medicine, University of Groningen, Groningen, The Netherlands.
  • Bansal M; Paediatric Intensive Care Unit, King's College Hospital, London, United Kingdom.
  • Hoskote A; Paediatric Intensive Care, SPS Hospitals, Ludhiana, India.
  • Javouhey E; Cardiac Intensive Care Unit, Heart and Lung Directorate, NIHR Great Ormond Street Hospital Biomedical Research Centre, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, United Kingdom.
  • Jourdain G; Paediatric Intensive Care Unit, Hospices Civils de Lyon, University of Lyon, Lyon, France.
  • Latten L; University Claude Bernard Lyon 1, Hospices Civils of Lyon, Lyon, France.
  • MacLaren G; Division of Paediatrics, Neonatal Critical Care and Transportation, Medical Centre "A.Béclère", Paris Saclay University Hospitals, APHP, Paris, France.
  • Morin L; Critical Care, Nutrition and Dietetics, Alder Hey Children's, NHS Foundation Trust, Liverpool, United Kingdom.
  • Pons-Odena M; Cardiothoracic ICU, National University Hospital, Singapore, Singapore.
  • Ricci Z; Paediatric Intensive Care Unit, Royal Children's Hospital, Melbourne, VIC, Australia.
  • Singh Y; Paediatric Intensive Care, AP-HP Paris-Saclay University, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
  • Schlapbach LJ; Department of Paediatric Intensive Care and Intermediate Care, Sant Joan de Déu University Hospital, Universitat de Barcelona, Esplugues de Llobregat, Spain.
  • Scholefield BR; Immune and Respiratory Dysfunction, Institut de Recerca Sant Joan de Déu, Santa Rosa 39-57, 08950 Esplugues de Llobregat, Spain.
  • Terheggen U; Paediatric Cardiac Intensive Care Unit, Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
  • Tissières P; Department of Paediatrics-Paediatric Cardiology and Neonatology, Cambridge University NHS Foundation Trust, Hospitals and University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
  • Tume LN; Child Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
  • Verbruggen S; Department of Intensive Care Medicine and Neonatology, and Children's Research Centre, University Children's Hospital of Zurich, University of Zurich, Zurich, Switzerland.
  • Brierley J; Department of Paediatric Intensive Care, Birmingham Children's Hospital, Birmingham, United Kingdom.
Pediatr Crit Care Med ; 22(1): 56-67, 2021 01 01.
Article in English | MEDLINE | ID: covidwho-1012891
ABSTRACT

OBJECTIVES:

In children, coronavirus disease 2019 is usually mild but can develop severe hypoxemic failure or a severe multisystem inflammatory syndrome, the latter considered to be a postinfectious syndrome, with cardiac involvement alone or together with a toxic shock like-presentation. Given the novelty of severe acute respiratory syndrome coronavirus 2, the causative agent of the recent coronavirus disease 2019 pandemic, little is known about the pathophysiology and phenotypic expressions of this new infectious disease nor the optimal treatment approach. STUDY SELECTION From inception to July 10, 2020, repeated PubMed and open Web searches have been done by the scientific section collaborative group members of the European Society of Pediatric and Neonatal Intensive Care. DATA EXTRACTION There is little in the way of clinical research in children affected by coronavirus disease 2019, apart from descriptive data and epidemiology. DATA

SYNTHESIS:

Even though basic treatment and organ support considerations seem not to differ much from other critical illness, such as pediatric septic shock and multiple organ failure, seen in PICUs, some specific issues must be considered when caring for children with severe coronavirus disease 2019 disease.

CONCLUSIONS:

In this clinical guidance article, we review the current clinical knowledge of coronavirus disease 2019 disease in critically ill children and discuss some specific treatment concepts based mainly on expert opinion based on limited experience and the lack of any completed controlled trials in children at this time.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Critical Illness / COVID-19 Type of study: Experimental Studies / Prognostic study / Reviews Limits: Child / Humans / Infant, Newborn Language: English Journal: Pediatr Crit Care Med Journal subject: Pediatrics / Critical Care Year: 2021 Document Type: Article Affiliation country: PCC.0000000000002599

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Critical Illness / COVID-19 Type of study: Experimental Studies / Prognostic study / Reviews Limits: Child / Humans / Infant, Newborn Language: English Journal: Pediatr Crit Care Med Journal subject: Pediatrics / Critical Care Year: 2021 Document Type: Article Affiliation country: PCC.0000000000002599