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Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers.
Català, Martí; Pino, David; Marchena, Miquel; Palacios, Pablo; Urdiales, Tomás; Cardona, Pere-Joan; Alonso, Sergio; López-Codina, David; Prats, Clara; Alvarez-Lacalle, Enrique.
  • Català M; Department of Physics, Universitat Politècnica de Catalunya (UPC ⋅ BarcelonaTech), Barcelona, Spain.
  • Pino D; Comparative Medicine and Bioimage Centre of Catalonia (CMCiB), Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Badalona, Catalonia, Spain.
  • Marchena M; Department of Physics, Universitat Politècnica de Catalunya (UPC ⋅ BarcelonaTech), Barcelona, Spain.
  • Palacios P; Department of Physics, Universitat Politècnica de Catalunya (UPC ⋅ BarcelonaTech), Barcelona, Spain.
  • Urdiales T; Department of Physics, Universitat Politècnica de Catalunya (UPC ⋅ BarcelonaTech), Barcelona, Spain.
  • Cardona PJ; Department of Physics, Universitat Politècnica de Catalunya (UPC ⋅ BarcelonaTech), Barcelona, Spain.
  • Alonso S; Comparative Medicine and Bioimage Centre of Catalonia (CMCiB), Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Badalona, Catalonia, Spain.
  • López-Codina D; Experimental Tuberculosis Unit (UTE), Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Universitat Autònoma de Barcelona (UAB), Badalona, Catalonia, Spain.
  • Prats C; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.
  • Alvarez-Lacalle E; Department of Physics, Universitat Politècnica de Catalunya (UPC ⋅ BarcelonaTech), Barcelona, Spain.
PLoS One ; 16(1): e0243701, 2021.
Article in English | MEDLINE | ID: covidwho-1060187
Preprint
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ABSTRACT
Policymakers need clear, fast assessment of the real spread of the COVID-19 epidemic in each of their respective countries. Standard measures of the situation provided by the governments include reported positive cases and total deaths. While total deaths indicate immediately that countries like Italy and Spain had the worst situation as of mid-April, 2020, reported cases alone do not provide a complete picture of the situation. Different countries diagnose differently and present very distinctive reported case fatality ratios. Similar levels of reported incidence and mortality might hide a very different underlying pictures. Here we present a straightforward and robust estimation of the diagnostic rate in each European country. From that estimation we obtain a uniform, unbiased incidence of the epidemic. The method to obtain the diagnostic rate is transparent and empirical. The key assumption of the method is that the infection fatality ratio of COVID-19 in Europe is not strongly country-dependent. We show that this number is not expected to be biased due to demography nor to the way total deaths are reported. The estimation protocol is dynamic, and it has been yielding converging numbers for diagnostic rates in all European countries as from mid-April, 2020. Using this diagnostic rate, policy makers can obtain Effective Potential Growth updated every day, providing an unbiased assessment of the countries at greater risk of experiencing an uncontrolled situation. The method developed has been and will be used to track possible improvements in the diagnostic rate in European countries as the epidemic evolves.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2021 Document Type: Article Affiliation country: Journal.pone.0243701

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2021 Document Type: Article Affiliation country: Journal.pone.0243701