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Explainable COVID-19 Detection Using Chest CT Scans and Deep Learning.
Alshazly, Hammam; Linse, Christoph; Barth, Erhardt; Martinetz, Thomas.
  • Alshazly H; Institute for Neuro- and Bioinformatics, University of Lübeck, 23562 Lübeck, Germany.
  • Linse C; Mathematics Department, Faculty of Science, South Valley University, Qena 83523, Egypt.
  • Barth E; Institute for Neuro- and Bioinformatics, University of Lübeck, 23562 Lübeck, Germany.
  • Martinetz T; Institute for Neuro- and Bioinformatics, University of Lübeck, 23562 Lübeck, Germany.
Sensors (Basel) ; 21(2)2021 Jan 11.
Article in English | MEDLINE | ID: covidwho-1022007
ABSTRACT
This paper explores how well deep learning models trained on chest CT images can diagnose COVID-19 infected people in a fast and automated process. To this end, we adopted advanced deep network architectures and proposed a transfer learning strategy using custom-sized input tailored for each deep architecture to achieve the best performance. We conducted extensive sets of experiments on two CT image datasets, namely, the SARS-CoV-2 CT-scan and the COVID19-CT. The results show superior performances for our models compared with previous studies. Our best models achieved average accuracy, precision, sensitivity, specificity, and F1-score values of 99.4%, 99.6%, 99.8%, 99.6%, and 99.4% on the SARS-CoV-2 dataset, and 92.9%, 91.3%, 93.7%, 92.2%, and 92.5% on the COVID19-CT dataset, respectively. For better interpretability of the results, we applied visualization techniques to provide visual explanations for the models' predictions. Feature visualizations of the learned features show well-separated clusters representing CT images of COVID-19 and non-COVID-19 cases. Moreover, the visualizations indicate that our models are not only capable of identifying COVID-19 cases but also provide accurate localization of the COVID-19-associated regions, as indicated by well-trained radiologists.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thorax / Tomography, X-Ray Computed / Deep Learning / COVID-19 Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Year: 2021 Document Type: Article Affiliation country: S21020455

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thorax / Tomography, X-Ray Computed / Deep Learning / COVID-19 Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Year: 2021 Document Type: Article Affiliation country: S21020455