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Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding.
Xu, Yi; Li, Xufang; Zhu, Bing; Liang, Huiying; Fang, Chunxiao; Gong, Yu; Guo, Qiaozhi; Sun, Xin; Zhao, Danyang; Shen, Jun; Zhang, Huayan; Liu, Hongsheng; Xia, Huimin; Tang, Jinling; Zhang, Kang; Gong, Sitang.
  • Xu Y; Department of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Li X; Department of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Zhu B; Department of Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Liang H; Clinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Fang C; Guangdong Provincial Children's Medical Research Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Gong Y; Department of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Guo Q; Department of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Sun X; Department of Medical Administration, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Zhao D; Department of Medical Administration, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Shen J; Department of Medical Administration, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Zhang H; Department of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Liu H; Department of Pediatric, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Xia H; Guangdong Provincial Children's Medical Research Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Tang J; Division of Neonatology and Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA, USA.
  • Zhang K; Department of Radiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
  • Gong S; Clinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. huiminxia@hotmail.com.
Nat Med ; 26(4): 502-505, 2020 04.
Article in English | MEDLINE | ID: covidwho-10221
ABSTRACT
We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection cases confirmed by real-time reverse transcription PCR assay of SARS-CoV-2 RNA. Symptoms in these cases were nonspecific and no children required respiratory support or intensive care. Chest X-rays lacked definite signs of pneumonia, a defining feature of the infection in adult cases. Notably, eight children persistently tested positive on rectal swabs even after nasopharyngeal testing was negative, raising the possibility of fecal-oral transmission.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Virus Shedding / Coronavirus Infections / Feces / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Limits: Child / Child, preschool / Female / Humans / Infant / Male Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2020 Document Type: Article Affiliation country: S41591-020-0817-4

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Virus Shedding / Coronavirus Infections / Feces / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Topics: Long Covid Limits: Child / Child, preschool / Female / Humans / Infant / Male Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2020 Document Type: Article Affiliation country: S41591-020-0817-4