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Diagnostic value of chest CT in Iranian patients with suspected COVID-19.
Salehi-Pourmehr, Hanieh; Pourfathi, Hojjat; Tarzamni, Mohammad Kazem; Ghojazadeh, Morteza; Naghili, Behrooz; Zarrintan, Armin; Mahdipour, Reza; Hajebrahimi, Sakineh.
  • Salehi-Pourmehr H; Research Center for Evidence-Based- Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Pourfathi H; Department of Anesthesiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Tarzamni MK; Department of Radiology, Medical Radiation Sciences Research Group, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Ghojazadeh M; Research Center for Evidence-Based- Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Naghili B; Research Center for Infectious and Tropical Disease, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Zarrintan A; Department of Radiology, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Mahdipour R; Research Center for Evidence-Based- Medicine, Iranian EBM Center: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Hajebrahimi S; Department of Urology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Caspian J Intern Med ; 11(Suppl 1): 527-530, 2020.
Article in English | MEDLINE | ID: covidwho-1022324
ABSTRACT

BACKGROUND:

In the current COVID-19 pandemic, there is a rising need for a rapid and reliable diagnostic tool. We hypothesized that chest computed tomography (CT) can be a potential alternative for reverse transcription-polymerase chain reaction (RT-PCR). The aim of this study was to compare the diagnostic value of chest CT and RT-PCR in Iranian patients with suspected COVID-19.

METHODS:

In a retrospective, single-center case series, 568 consecutive hospitalized or outpatient patients with suspected COVID-19 underwent chest CT and/or RT-PCR testing at Imam Reza Hospital, the tertiary teaching hospital of Tabriz University of Medical Sciences in Iran, from February 21 and March 28, 2020.

RESULTS:

The sensitivity of chest CT for signifying COVID-19 was 64% (95% CI 56%-71%) on the basis of positive RT-PCR results as a standard method. CT imaging also had a specificity of 77% (95% CI 73%-81%), positive predictive value of 35% (95% CI 0.31-0.39), negative predictive value of 66% (95% CI 0.61-0.69), positive likelihood ratio of 2.79 (95% CI 2.26-3.46), and negative likelihood ratio of 0.47 (95% CI 0.38-0.57).

CONCLUSION:

Chest CT had higher specificity in the diagnosis of COVID-19 than that of the previous studies. Therefore, it can play a crucial role in the early diagnosis. Similar to the previous studies, the typical CT features were patchy ground-glass opacities as well as peripheral aspects of the lungs consolidations.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Observational study / Prognostic study Language: English Journal: Caspian J Intern Med Year: 2020 Document Type: Article Affiliation country: Cjim.11.0.527

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Observational study / Prognostic study Language: English Journal: Caspian J Intern Med Year: 2020 Document Type: Article Affiliation country: Cjim.11.0.527