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SARS-CoV-2 associated ischemic stroke: first case report in Peru
Rev. neuropsiquiatr ; 83(2):127-133, 2020.
Article in Spanish | LILACS (Americas) | ID: covidwho-1022922
ABSTRACT
Resumen La enfermedad causada por el coronavirus 2 asociado al síndrome respiratorio agudo grave (SARS-CoV-2) se conoce como Coronavirus Disease-2019 (COVID-19). Su afectación es principalmente respiratoria, pero se han descrito diversas manifestaciones neurológicas. El neurotropismo y potencial rol neuropatógeno del SARS-CoV-2, se plantea en base a modelos en animales y casos de afección neurológica descritos en otros coronavirus, así como por reportes recientes de síndromes neurológicos específicos relacionados a COVID-19, incluido el accidente cerebrovascular (ACV). La sociedad española de neurología (SEN) describió a los ACV isquémicos como la segunda manifestación neurológica más frecuente en pacientes con COVID-19. Se reconoce que el estado de hiperinflamación e hipercoagulabilidad sanguínea desencadenada por el COVID-19 incrementaría el riesgo de eventos protrombóticos. Reportamos 3 casos de pacientes peruanos que presentaron ACV isquémico asociado a COVID-19 describimos el cuadro clínico, exámenes paraclínicos y revisamos la literatura mundial. The disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is known as Coronavirus Disease 2019 (COVID-19). Its involvement is mainly respiratory, but various neurological manifestations have been described. The neurotropism and potential neuropathotogenic role of SARS-CoV-2 is based on animal models and cases of neurological condition described in other coronaviruses, as well as recent reports of specific neurological syndromes related to COVID-19, including ischemic stroke. The Spanish Society of Neurology described ischemic stroke as the second most frequent neurological manifestation in patients with COVID-19. Likewise, the state of hyperinflammation and blood hypercoagulability triggered by COVID-19 would increase the risk of prothrombotic events. We report 3 cases of peruvian patients who presented ischemic stroke associated with COVID-19 we describe the clinical manifestations, paraclinical examinations and review the world literature.
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Collection: Databases of international organizations Database: LILACS (Americas) Type of study: Risk factors Country/Region as subject: South America / Peru Language: Spanish Journal: Rev. neuropsiquiatr Year: 2020 Document Type: Article

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Collection: Databases of international organizations Database: LILACS (Americas) Type of study: Risk factors Country/Region as subject: South America / Peru Language: Spanish Journal: Rev. neuropsiquiatr Year: 2020 Document Type: Article