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Persistence of SARS-CoV-2 RNA in post-mortem swab 35 days after death: A case report.
Beltempo, Pasquale; Curti, Serena Maria; Maserati, Renato; Gherardi, Mirella; Castelli, Maurizio.
  • Beltempo P; S.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: pbeltempo@ausl.vda.it.
  • Curti SM; S.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: scurti@ausl.vda.it.
  • Maserati R; Dipartimento Scienze mediche e malattie infettive, Fondazione IRCCS Policlinico "San Matteo", Piazzale Golgi 19, 27100, Pavia (PV), Italy. Electronic address: rmaserati@smatteo.pv.it.
  • Gherardi M; S.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: mgherardi@ausl.vda.it.
  • Castelli M; S.C. Medicina Legale, Azienda USL Valle d'Aosta, Località Amerique 7/L, 11020, Quart (AO), Italy. Electronic address: mcastelli@ausl.vda.it.
Forensic Sci Int ; 319: 110653, 2021 Feb.
Article in English | MEDLINE | ID: covidwho-1023567
ABSTRACT
Post-mortem swabs for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA detection have been recommended by several Scientific Committees and Institutions as a standard procedure for post-mortem assessment of potential Coronavirus Disease-19 (COVID-19) related deaths. To date there is no data about the SARS-CoV-2 RNA detectability period in human bodies after death. The present case documents the persistence of SARS-CoV-2 RNA in the upper respiratory tract 35-days after death. Post-mortem swabs could be used as a valuable tool in preventive evaluation of the risks-benefits ratio associated with autopsy execution. SARS-CoV-2 RNA post-mortem detection could have a key diagnostic role in deaths lacking medical assistance, unattended deaths, and patients with multiple comorbidities. Based on the present report, staged post-mortem swabs should be performed even after a long post-mortem interval.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Oropharynx / Cadaver / RNA, Viral / SARS-CoV-2 / Nasal Cavity Type of study: Case report / Experimental Studies / Prognostic study Limits: Humans / Male / Middle aged Language: English Journal: Forensic Sci Int Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Oropharynx / Cadaver / RNA, Viral / SARS-CoV-2 / Nasal Cavity Type of study: Case report / Experimental Studies / Prognostic study Limits: Humans / Male / Middle aged Language: English Journal: Forensic Sci Int Year: 2021 Document Type: Article