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The bioenergetics of COVID-19 immunopathology and the therapeutic potential of biophysical radiances.
Surazakov, Arzhan; Klassen, Anna; Gizinger, Oksana.
  • Surazakov A; Radiant Life Technologies, Ltd., 10 Chalkokondyli Street, Amaral 7, Office 101 Lykavitos, P.C.1071 Nicosia, Cyprus. Electronic address: arzhan@radiant-life-technologies.com.
  • Klassen A; No affiliation, Valdayskaya 73, pos. Belmesevo, Barnaul, 656901, Russia.
  • Gizinger O; Department of Microbiology and Virology, Department of Immunology and Allergology, Medical Institute, RUDN University, Moscow, Russia.
J Photochem Photobiol B ; 213: 112083, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-1023667
ABSTRACT
In developing an effective clinical tool against COVID-19, we need to consider why SARS-CoV-2 infections develop along remarkably different trajectories from completely asymptomatic to a severe course of disease. In this paper we hypothesize that the progressive exhaustion and loss of lymphocytes associated with severe stages of COVID-19 result from an intracellular energy deficit in an organism which has already been depleted by preexisting chronic diseases, acute psychological stress and the aging process. A bioenergetics view of COVID-19 immunopathology opens a new biophysical opportunity to enhance impaired immune function via proposed pathways of photomagnetic catalysis of ATP synthesis, regenerative photobiomodulation and the ultrasonic acceleration of cell restructuring. Moreover, we suggest that a coherent application of multiple biophysical radiances (coMra) may synergistically enhance energy-matter-information kinetics of basal self-regeneration of cells and thus improve immune function and accelerate recovery.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Ultrasonic Therapy / Low-Level Light Therapy / Energy Metabolism / Biophysical Phenomena / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: J Photochem Photobiol B Journal subject: Biology Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Ultrasonic Therapy / Low-Level Light Therapy / Energy Metabolism / Biophysical Phenomena / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: J Photochem Photobiol B Journal subject: Biology Year: 2020 Document Type: Article