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ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection.
Liu, Furong; Long, Xin; Zhang, Bixiang; Zhang, Wanguang; Chen, Xiaoping; Zhang, Zhanguo.
  • Liu F; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China.
  • Long X; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China.
  • Zhang B; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China.
  • Zhang W; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China.
  • Chen X; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China.
  • Zhang Z; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China. Electronic address: zhanguo_tjh@hust.edu.cn.
Clin Gastroenterol Hepatol ; 18(9): 2128-2130.e2, 2020 08.
Article in English | MEDLINE | ID: covidwho-102388
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus that causes coronavirus disease 2019 (COVID-19) in human beings, has caused a serious public health issue.1 Attention to pancreatic injury is lacking, which may impact patients' prognosis. In this study, we explored the expression and distribution of angiotensin-converting enzyme 2 (ACE2), the receptor of SARS-CoV-2, in the pancreas. Combined with clinical data, we showed that pancreatic injury can occur in some COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pancreas / Pancreatic Diseases / Pneumonia, Viral / Receptors, Virus / Coronavirus Infections / Peptidyl-Dipeptidase A / Gene Expression Profiling / Betacoronavirus Type of study: Prognostic study Topics: Long Covid Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Language: English Journal: Clin Gastroenterol Hepatol Journal subject: Gastroenterology Year: 2020 Document Type: Article Affiliation country: J.cgh.2020.04.040

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pancreas / Pancreatic Diseases / Pneumonia, Viral / Receptors, Virus / Coronavirus Infections / Peptidyl-Dipeptidase A / Gene Expression Profiling / Betacoronavirus Type of study: Prognostic study Topics: Long Covid Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Language: English Journal: Clin Gastroenterol Hepatol Journal subject: Gastroenterology Year: 2020 Document Type: Article Affiliation country: J.cgh.2020.04.040