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SCOR: A secure international informatics infrastructure to investigate COVID-19.
Raisaro, J L; Marino, Francesco; Troncoso-Pastoriza, Juan; Beau-Lejdstrom, Raphaelle; Bellazzi, Riccardo; Murphy, Robert; Bernstam, Elmer V; Wang, Henry; Bucalo, Mauro; Chen, Yong; Gottlieb, Assaf; Harmanci, Arif; Kim, Miran; Kim, Yejin; Klann, Jeffrey; Klersy, Catherine; Malin, Bradley A; Méan, Marie; Prasser, Fabian; Scudeller, Luigia; Torkamani, Ali; Vaucher, Julien; Puppala, Mamta; Wong, Stephen T C; Frenkel-Morgenstern, Milana; Xu, Hua; Musa, Baba Maiyaki; Habib, Abdulrazaq G; Cohen, Trevor; Wilcox, Adam; Salihu, Hamisu M; Sofia, Heidi; Jiang, Xiaoqian; Hubaux, J P.
  • Raisaro JL; Data Science Group and Precision Medicine Unit, Lausanne University Hospital, Lausanne, Switzerland.
  • Marino F; Laboratory for Data Security, EPFL, Lausanne, Switzerland.
  • Troncoso-Pastoriza J; Laboratory for Data Security, EPFL, Lausanne, Switzerland.
  • Beau-Lejdstrom R; Institute of Global Health, University of Geneva, Geneva, Switzerland.
  • Bellazzi R; Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy.
  • Murphy R; IRCCS ICS Maugeri, Pavia, Italy.
  • Bernstam EV; School of Biomedical Informatics, UTHealth, Houston, Texas, USA.
  • Wang H; School of Biomedical Informatics, UTHealth, Houston, Texas, USA.
  • Bucalo M; Division of General Internal Medicine, Department of Internal Medicine, McGovern School of Medicine, UTHealth, Houston, Texas, USA.
  • Chen Y; Department of Emergency Medicine, McGovern School of Medicine, UTHealth, Houston, Texas, USA.
  • Gottlieb A; BIOMERIS srl, Pavia, Italy.
  • Harmanci A; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Kim M; School of Biomedical Informatics, UTHealth, Houston, Texas, USA.
  • Kim Y; School of Biomedical Informatics, UTHealth, Houston, Texas, USA.
  • Klann J; School of Biomedical Informatics, UTHealth, Houston, Texas, USA.
  • Klersy C; School of Biomedical Informatics, UTHealth, Houston, Texas, USA.
  • Malin BA; Laboratory of Computer Science, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Méan M; Biometry and Clinical Epidemiology Service, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
  • Prasser F; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Scudeller L; Department of Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland.
  • Torkamani A; Medical Informatics Group, Berlin Institute of Health, Berlin, Germany.
  • Vaucher J; Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Puppala M; Scientific Direction, Clinical Epidemiology and Biostatistics, Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico, Milan, Italy.
  • Wong STC; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, California, USA.
  • Frenkel-Morgenstern M; Department of Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland.
  • Xu H; Department of Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Weill Cornell Medical College, Houston, Texas, USA.
  • Musa BM; Department of Systems Medicine and Bioengineering, Houston Methodist Cancer Center, Weill Cornell Medical College, Houston, Texas, USA.
  • Habib AG; Cancer Genomics and BioComputing of Complex Diseases laboratory, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
  • Cohen T; School of Biomedical Informatics, UTHealth, Houston, Texas, USA.
  • Wilcox A; Department of Medicine, Africa Center of Excellence in Population Health and Policy, Bayero University, Kano, Nigeria.
  • Salihu HM; Department of Medicine, Africa Center of Excellence in Population Health and Policy, Bayero University, Kano, Nigeria.
  • Sofia H; Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA.
  • Jiang X; Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA.
  • Hubaux JP; Department of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
J Am Med Inform Assoc ; 27(11): 1721-1726, 2020 11 01.
Article in English | MEDLINE | ID: covidwho-1024117
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ABSTRACT
Global pandemics call for large and diverse healthcare data to study various risk factors, treatment options, and disease progression patterns. Despite the enormous efforts of many large data consortium initiatives, scientific community still lacks a secure and privacy-preserving infrastructure to support auditable data sharing and facilitate automated and legally compliant federated analysis on an international scale. Existing health informatics systems do not incorporate the latest progress in modern security and federated machine learning algorithms, which are poised to offer solutions. An international group of passionate researchers came together with a joint mission to solve the problem with our finest models and tools. The SCOR Consortium has developed a ready-to-deploy secure infrastructure using world-class privacy and security technologies to reconcile the privacy/utility conflicts. We hope our effort will make a change and accelerate research in future pandemics with broad and diverse samples on an international scale.
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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Pneumonia, Viral / Computer Security / Coronavirus Infections / Privacy / Information Dissemination / Biomedical Research / Pandemics Subject: Pneumonia, Viral / Computer Security / Coronavirus Infections / Privacy / Information Dissemination / Biomedical Research / Pandemics Type of study: Prognostic study / Risk factors Language: English Journal: J Am Med Inform Assoc Clinical aspect: Etiology Year: 2020

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Pneumonia, Viral / Computer Security / Coronavirus Infections / Privacy / Information Dissemination / Biomedical Research / Pandemics Subject: Pneumonia, Viral / Computer Security / Coronavirus Infections / Privacy / Information Dissemination / Biomedical Research / Pandemics Type of study: Prognostic study / Risk factors Language: English Journal: J Am Med Inform Assoc Clinical aspect: Etiology Year: 2020
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