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Coronavirus Disease 2019 (COVID-19) in a Patient with Disseminated Histoplasmosis and HIV-A Case Report from Argentina and Literature Review.
Messina, Fernando A; Marin, Emmanuel; Caceres, Diego H; Romero, Mercedes; Depardo, Roxana; Priarone, Maria M; Rey, Laura; Vázquez, Mariana; Verweij, Paul E; Chiller, Tom M; Santiso, Gabriela.
  • Messina FA; Unidad de Micología, Hospital de Infecciosas F. J. Muñiz B.A. Uspallata 2272, C1282 CABA, Argentina.
  • Marin E; Unidad de Micología, Hospital de Infecciosas F. J. Muñiz B.A. Uspallata 2272, C1282 CABA, Argentina.
  • Caceres DH; Mycotic Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.
  • Romero M; Department of Medical Microbiology, Radboud University Medical Center and Center of Expertise in Mycology Radboudumc/CWZ, 9101 Nijmegen, The Netherlands.
  • Depardo R; Unidad de Micología, Hospital de Infecciosas F. J. Muñiz B.A. Uspallata 2272, C1282 CABA, Argentina.
  • Priarone MM; Unidad de Micología, Hospital de Infecciosas F. J. Muñiz B.A. Uspallata 2272, C1282 CABA, Argentina.
  • Rey L; División de HIV SIDA, Hospital de Infecciosas F. J. Muñiz B.A., Uspallata 2272, C1282 CABA, Argentina.
  • Vázquez M; División de Neumonología, Hospital de Infecciosas F. J. Muñiz B.A., Uspallata 2272, C1282 CABA, Argentina.
  • Verweij PE; Bacteriología de Guardia, Hospital de Infecciosas F. J. Muñiz B.A., Uspallata 2272, C1282 CABA, Argentina.
  • Chiller TM; Department of Medical Microbiology, Radboud University Medical Center and Center of Expertise in Mycology Radboudumc/CWZ, 9101 Nijmegen, The Netherlands.
  • Santiso G; Mycotic Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA.
J Fungi (Basel) ; 6(4)2020 Nov 10.
Article in English | MEDLINE | ID: covidwho-1024594
ABSTRACT
The disease caused by the new SARS-CoV-2, known as Coronavirus disease 2019 (COVID-19), was first identified in China in December 2019 and rapidly spread around the world. Coinfections with fungal pathogens in patients with COVID-19 add challenges to patient care. We conducted a literature review on fungal coinfections in patients with COVID-19. We describe a report of a patient with disseminated histoplasmosis who was likely infected with SARS-CoV-2 and experienced COVID-19 during hospital care in Buenos Aires, Argentina. This patient presented with advanced HIV disease, a well-known factor for disseminated histoplasmosis; on the other hand, we suspected that COVID-19 was acquired during hospitalization but there is not enough evidence to support this hypothesis. Clinical correlation and the use of specific Histoplasma and COVID-19 rapid diagnostics assays were key to the timely diagnosis of both infections, permitting appropriate treatment and patient care.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study / Reviews Country/Region as subject: South America / Argentina Language: English Year: 2020 Document Type: Article Affiliation country: Jof6040275

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study / Reviews Country/Region as subject: South America / Argentina Language: English Year: 2020 Document Type: Article Affiliation country: Jof6040275