Longitudinal Monitoring of Lactate in Hospitalized and Ambulatory COVID-19 Patients.
Am J Trop Med Hyg
; 104(3): 1041-1044, 2021 Jan 11.
Article
in English
| MEDLINE | ID: covidwho-1024748
ABSTRACT
Hypoxemia is readily detectable by assessing SpO2 levels, and these are important in optimizing COVID-19 patient management. Hyperlactatemia is a marker of tissue hypoxia, particularly in patients with increased oxygen requirement and microvascular obstruction. We monitored peripheral venous lactate concentrations in hospitalized patients with moderate to severe COVID-19 (n = 18) and in mild ambulatory COVID-19 patients in home quarantine (n = 16). Whole blood lactate decreased significantly during the clinical course and recovery in hospitalized patients (P = 0.008). The blood lactate levels were significantly higher in hospitalized patients than ambulatory patients (day 1 hospitalized versus ambulatory patients P = 0.002; day 28 hospitalized versus ambulatory patients P = < 0.0001). Elevated lactate levels may be helpful in risk stratification, and serial monitoring of lactate may prove useful in the care of hospitalized COVID-19 patients.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Lactic Acid
/
Ambulatory Care Facilities
/
COVID-19
/
Hospitalization
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
/
Young adult
Country/Region as subject:
Europa
Language:
English
Journal:
Am J Trop Med Hyg
Year:
2021
Document Type:
Article
Affiliation country:
Ajtmh.20-1282
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