Side effects of lopinavir/ritonavir for COVID-19
Chinese Journal of Clinical Pharmacology and Therapeutics
; 25(11):1283-1287, 2020.
Article
in Chinese
| EMBASE | ID: covidwho-1024781
ABSTRACT
AIM:
To study the regularity and characteristics of side effects of lopinavir/ritonavir for COVID-19.METHODS:
The type of side effects, general information, medical history and prognosis in 61 confirmed and suspected COVID-19 patients with lopinavir/ritonavir were analyzed.RESULTS:
Among the 61 patients, 41(67.21%) had lopinavir/ritonavir related side effects, mainly manifested as gastrointestinal reactions (82.93%) and liver function damage (53.66%). Old age, long course of disease and chronic gastrointestinal disease are independent risk factors for side effects.CONCLUSION:
Lopinavir/ritonavir has a high incidence of side effects and can be used in COVID-19 patients under the condition of close observation of the patient's symptoms and test results. Special population should improve pharmaceutical care to ensure the safety of drug use.
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Experimental Studies
Language:
Chinese
Journal:
Chinese Journal of Clinical Pharmacology and Therapeutics
Year:
2020
Document Type:
Article
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