Clinical efficacy of traditional Chinese medicine Lianhua Qingwen Granules in 42 suspected cases of children with Corona Virus Disease 2019

ABSTRACT

Objective: To evaluate the clinical efficacy of traditional Chinese medicine Lianhua Qingwen Granules in treating suspected cases of children with Corona Virus Disease 2019. Methods: Clinical retrospective study method was used to collect 83 cases of common type children who met the diagnostic criteria of suspected cases of Corona Virus Disease 2019 and were admitted to Xiangyang No.1 People's Hospital from January 28, 2020 to March 31. Among them, 42 patients in the treatment group received routine treatment (antiviral and symptomatic support treatment, combined with antibacterial treatment for infected patients) combined with traditional Chinese medicine Lianhua Qingwen Granules. The control group of 41 patients received routine treatment only. Clinical data were collected after 5 d of treatment, and the disappearance of main symptoms (fever and cough), the duration of fever, and other single symptoms (cough, nasal obstruction, runny nose, shortness of breath, muscle pain, and gastrointestinal symptoms) were compared between the two groups. Results: The disappearance rates of fever and cough in the treatment group were 83.3% and 57.9%, respectively, and those in the control group were 51.2% and 30.3%, respectively. The treatment group was significantly better than the control group (P<0.05). The disappearance rates of phlegm, shortness of breath and digestive tract symptoms in the treatment group were 66.7%, 100% and 87.5%, respectively, and those in the control group were 20%, 60% and 28.6%, respectively, with significant increases (P<0.05). Conclusion: Traditional Chinese medicine Lianhua Qingwen Granules can significantly improve fever, cough, phlegm, shortness of breath and gastrointestinal symptoms in children suspected of Corona Virus Disease 2019, providing preliminary clinical evidence for the prevention and treatment of pediatric cases.