Your browser doesn't support javascript.
Yield of Screening for COVID-19 in Asymptomatic Patients Before Elective or Emergency Surgery Using Chest CT and RT-PCR (SCOUT): Multicenter Study.
Puylaert, Carl A J; Scheijmans, Jochem C G; Borgstein, Alexander B J; Andeweg, Caroline S; Bartels-Rutten, Annemarieke; Beets, Geerard L; van Berge Henegouwen, Mark I; Braak, Sicco J; Couvreur, Roy; Daams, Freek; van Es, Hendrik W; Franken, Lotte C; Grotenhuis, Brechtje A; Hendriks, Eduard R; de Hingh, Ignace H J T; Hoeijmakers, Fieke; Ten Holder, Joris T; Huisman, Peter M; Kazemier, Geert; van Kesteren, Floortje; van Kesteren, Jurre; Keywani, Kammy; Kuiper, Sara Z; Lange, Maurits D J; Lobatto, Mark E; du Mée, Arthur W F; Poeze, Martijn; van Praag, Elise M; van Rossen, Jorit; van Santvoort, Hjalmar C; Sedee, Wouter J A; Seelen, Leonard W F; Sharabiany, Sarah; Sosef, Nico L; Quanjel, Marian J R; Veltman, Jeroen; Verhagen, Tim; van de Vlasakker, Vincent C J; Weeder, Pepijn D; van Werven, Jochem R; Wesdorp, Nina J; van Dieren, Susan; Han, Alvin X; Russell, Colin A; de Jong, Menno D; Bossuyt, Patrick M M; Quarles van Ufford, Jet M E; Prokop, Mathias W; Gisbertz, Suzanne S; Prins, Jan M.
  • Puylaert CAJ; Department of Radiology and Nuclear Medicine, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Scheijmans JCG; Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Borgstein ABJ; Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Andeweg CS; Department of Surgery, St Jansdal Hospital, Harderwijk, the Netherlands.
  • Bartels-Rutten A; Department of Radiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Beets GL; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • van Berge Henegouwen MI; Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Braak SJ; Department of Radiology, Hospital Group Twente, Almelo, the Netherlands.
  • Couvreur R; Department of Surgery, Haaglanden Medical Center, Den Haag, the Netherlands.
  • Daams F; Department of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands.
  • van Es HW; Department of Radiology, Sint Antonius Hospital, Nieuwegein, the Netherlands.
  • Franken LC; Department of Surgery, Flevo Hospital, Almere, the Netherlands.
  • Grotenhuis BA; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Hendriks ER; Department of Surgery, Tergooi Hospitals, Hilversum, the Netherlands.
  • de Hingh IHJT; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.
  • Hoeijmakers F; Department of Surgery, Dijklander Hospital, Hoorn, the Netherlands.
  • Ten Holder JT; Department of Pulmonary Medicine, Haaglanden Medical Center, Den Haag, the Netherlands.
  • Huisman PM; Department of Radiology, Tergooi Hospitals, Hilversum, the Netherlands.
  • Kazemier G; Department of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands.
  • van Kesteren F; Department of Radiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • van Kesteren J; Department of Surgery, Dijklander Hospital, Hoorn, the Netherlands.
  • Keywani K; Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Kuiper SZ; Department of Surgery, Maastricht UMC+, Maastricht, the Netherlands.
  • Lange MDJ; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Lobatto ME; Department of Radiology, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands.
  • du Mée AWF; Department of Radiology, Amphia Hospital, Breda, the Netherlands.
  • Poeze M; Department of Surgery, Maastricht UMC+, Maastricht, the Netherlands.
  • van Praag EM; Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • van Rossen J; Department of Radiology, Hospital Group Twente, Almelo, the Netherlands.
  • van Santvoort HC; Department of Surgery, Sint Antonius Hospital, Nieuwegein, the Netherlands.
  • Sedee WJA; Department of Surgery, UMC Utrecht Cancer Center, UMC Utrecht, Utrecht, the Netherlands.
  • Seelen LWF; Department of Emergency Medicine, St Jansdal Hospital, Harderwijk, the Netherlands.
  • Sharabiany S; Department of Surgery, Sint Antonius Hospital, Nieuwegein, the Netherlands.
  • Sosef NL; Department of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Quanjel MJR; Department of Surgery, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands.
  • Veltman J; Department of Pulmonary Medicine, Sint Antonius Hospital, Nieuwegein, the Netherlands.
  • Verhagen T; Department of Radiology, Hospital Group Twente, Almelo, the Netherlands.
  • van de Vlasakker VCJ; Department of Surgery, Hospital Group Twente, Almelo, the Netherlands.
  • Weeder PD; Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.
  • van Werven JR; Department of Surgery, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands.
  • Wesdorp NJ; Department of Radiology, Amphia Hospital, Breda, the Netherlands.
  • van Dieren S; Department of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands.
  • Han AX; Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Russell CA; Laboratory of Applied Evolutionary Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • de Jong MD; Laboratory of Applied Evolutionary Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Bossuyt PMM; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Quarles van Ufford JME; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Prokop MW; Department of Radiology, Haaglanden Medical Center, Den Haag, the Netherlands.
  • Gisbertz SS; Department of Radiology, Radboud UMC, Nijmegen, the Netherlands.
  • Prins JM; Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Ann Surg ; 272(6): 919-924, 2020 12.
Article in English | MEDLINE | ID: covidwho-1029777
ABSTRACT

OBJECTIVE:

To determine the yield of preoperative screening for COVID-19 with chest CT and RT-PCR in patients without COVID-19 symptoms. SUMMARY OF BACKGROUND DATA Many centers are currently screening surgical patients for COVID-19 using either chest CT, RT-PCR or both, due to the risk for worsened surgical outcomes and nosocomial spread. The optimal design and yield of such a strategy are currently unknown.

METHODS:

This multicenter study included consecutive adult patients without COVID-19 symptoms who underwent preoperative screening using chest CT and RT-PCR before elective or emergency surgery under general anesthesia.

RESULTS:

A total of 2093 patients without COVID-19 symptoms were included in 14 participating centers; 1224 were screened by CT and RT-PCR and 869 by chest CT only. The positive yield of screening using a combination of chest CT and RT-PCR was 1.5% [95% confidence interval (CI) 0.8-2.1]. Individual yields were 0.7% (95% CI 0.2-1.1) for chest CT and 1.1% (95% CI 0.6-1.7) for RT-PCR; the incremental yield of chest CT was 0.4%. In relation to COVID-19 community prevalence, up to ∼6% positive RT-PCR was found for a daily hospital admission rate >1.5 per 100,000 inhabitants, and around 1.0% for lower prevalence.

CONCLUSIONS:

One in every 100 patients without COVID-19 symptoms tested positive for SARS-CoV-2 with RT-PCR; this yield increased in conjunction with community prevalence. The added value of chest CT was limited. Preoperative screening allowed us to take adequate precautions for SARS-CoV-2 positive patients in a surgical population, whereas negative patients needed only routine procedures.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Surgical Procedures, Operative / Thorax / Preoperative Care / Tomography, X-Ray Computed / Mass Screening / Reverse Transcriptase Polymerase Chain Reaction / Emergency Treatment / Asymptomatic Infections / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: Ann Surg Year: 2020 Document Type: Article Affiliation country: SLA.0000000000004218

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Surgical Procedures, Operative / Thorax / Preoperative Care / Tomography, X-Ray Computed / Mass Screening / Reverse Transcriptase Polymerase Chain Reaction / Emergency Treatment / Asymptomatic Infections / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: Ann Surg Year: 2020 Document Type: Article Affiliation country: SLA.0000000000004218