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Optical technologies for the detection of viruses like COVID-19: Progress and prospects.
Lukose, Jijo; Chidangil, Santhosh; George, Sajan D.
  • Lukose J; Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal, 576 104, India; Centre of Excellence for Biophotonics, Manipal Academy of Higher Education, Manipal, 576 104, India.
  • Chidangil S; Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal, 576 104, India; Centre of Excellence for Biophotonics, Manipal Academy of Higher Education, Manipal, 576 104, India.
  • George SD; Department of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal, 576 104, India; Centre for Applied Nanosciences, Manipal Academy of Higher Education, Manipal, 576 104, India. Electronic address: sajan.george@manipal.edu.
Biosens Bioelectron ; 178: 113004, 2021 Apr 15.
Article in English | MEDLINE | ID: covidwho-1032329
ABSTRACT
The outbreak of life-threatening pandemic like COVID-19 necessitated the development of novel, rapid and cost-effective techniques that facilitate detection of viruses like SARS-CoV-2. The presently popular approach of a collection of samples using the nasopharyngeal swab method and subsequent detection of RNA using the real-time polymerase chain reaction suffers from false-positive results and a longer diagnostic time scale. Alternatively, various optical techniques namely optical sensing, spectroscopy, and imaging shows a great promise in virus detection. Herein, a comprehensive review of the various photonics technologies employed for virus detection, particularly the SARS-CoV family, is discussed. The state-of-art research activities in utilizing the photonics tools such as near-infrared spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, fluorescence-based techniques, super-resolution microscopy, surface plasmon resonance-based detection, for virus detection accounted extensively with an emphasis on coronavirus detection. Further, an account of emerging photonics technologies of SARS-CoV-2 detection and future possibilities is also explained. The progress in the field of optical techniques for virus detection unambiguously show a great promise in the development of rapid photonics-based devices for COVID-19 detection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Testing / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study Topics: Long Covid Limits: Humans Language: English Journal: Biosens Bioelectron Journal subject: Biotechnology Year: 2021 Document Type: Article Affiliation country: J.bios.2021.113004

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Testing / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study Topics: Long Covid Limits: Humans Language: English Journal: Biosens Bioelectron Journal subject: Biotechnology Year: 2021 Document Type: Article Affiliation country: J.bios.2021.113004