Do not neglect SARS-CoV-2 hospitalization and fatality risks in the middle-aged adult population.
Infect Dis Now
; 51(4): 380-382, 2021 Jun.
Article
in English
| MEDLINE | ID: covidwho-1033154
ABSTRACT
OBJECTIVES:
This study aimed at estimating the SARS-CoV-2 infection hospitalization (IHR) and infection fatality ratios (IFR) in France. PATIENTS ANDMETHODS:
A serosurvey was conducted in 9782 subjects from the two French regions with the highest incidence of COVID-19 during the first wave of the pandemic and coupled with surveillance data.RESULTS:
IHR and IFR were 2.7% and 0.49% overall. Both were higher in men and increased exponentially with age. The relative risks of hospitalization and death were 2.1 (95% CI 1.9-2.3) and 3.8 (2.4-4.2) per 10-year increase, meaning that IHR and IFR approximately doubled every 10 and 5 years, respectively. They were dramatically high in the very elderly (80-90 years IHR 26%, IFR 9.2%), and also substantial in younger adults (40-50 years IHR 0.98%, IFR 0.042%).CONCLUSIONS:
These findings support the need for comprehensive preventive measures to help reduce the spread of the virus, even in young or middle-aged adults.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Hospitalization
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
/
Young adult
Country/Region as subject:
Europa
Language:
English
Journal:
Infect Dis Now
Year:
2021
Document Type:
Article
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