Lithium chloride for the novel coronavirus infection covid-19
Russian Journal of Anesthesiology and Reanimatology
; 6(2):40-44, 2020.
Article
in Russian
| Scopus | ID: covidwho-1034349
ABSTRACT
The novel coronavirus infection COVID-19 is associated with increased release of inflammatory cytokines (cytokine storm) and reactive oxygen species. These processes result a damage to the endothelium, pulmonary alveolar epithelium and their basal membranes (including the structures of blood-air barrier), increased vascular permeability and non-cardiogenic pulmonary edema. These mechanisms underlie the pathogenesis of acute respiratory distress syndrome in patients with coronavirus infection COVID-19. In this review, we have analyzed the data on the effect of lithium chloride on cytokine storm, increased vascular endothelial permeabili-ty, apoptosis of endotheliocyte and advanced activation of innate immune cells in patients with coronavirus infection COVID-19. © 2020, Media Sphera. All rights reserved.
Full text:
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Collection:
Databases of international organizations
Database:
Scopus
Language:
Russian
Journal:
Russian Journal of Anesthesiology and Reanimatology
Year:
2020
Document Type:
Article
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