Critically ill neurologic patients during the COVID-19 pandemic: A short communication.
Brain Behav Immun Health
; 12: 100207, 2021 Mar.
Article
in English
| MEDLINE | ID: covidwho-1037050
ABSTRACT
PURPOSE:
We aimed to evaluate utilization of inpatient hospital and critical care services among critically ill neurologic patients during the COVID-19 pandemic. We hypothesized, based on prior observations among ischemic stroke patients, that there would be significant decline in critically ill neurologic patients presenting to hospitals during the pandemic which may impact outcomes.METHODS:
We used TriNetX, a large research network, collecting real-time electronic medical records data. We extracted data on utilization of critical care and hospital inpatient services among cohorts of patients with common neurocritical conditions between January-June 2020 and compared it to data from similar time-frames in previous years. We also compared clinical outcomes, comprising need for intubation and 30-day mortality, among these cohorts.RESULTS:
We found a 28.1% reduction in intensive care unit (ICU) admissions with critical neurologic illnesses in 2020 when compared to 2019 (8568 vs. 11,917 patients, p â< â0.0001) and a 34.4% reduction compared to 2018 (8568 vs. 13,064 patients, p â< â0.0001). However, there was no statistically significant difference in mortality (2020 12.2 vs. 2019 12.4%; p â= â0.7; vs. 2018 12.6%; p â= â0.62) or intubation rates across the years among patients using critical care services. There was 1% increase in mortality among non-ICU patients with similar diagnoses in 2020 compared to previous years (2020 3.9% vs. 2019 2.9% vs. 2018 3.1%; p â< â0.0001, p â= â0.0001), but no difference in intubation rates.CONCLUSION:
There was a significant reduction in hospital and ICU admissions among patients with acute neurologic emergencies in 2020, after onset of COVID-19 pandemic, compared to previous years. While we did not find a significant difference in mortality among patients admitted to the ICU, there was slightly higher mortality among non-ICU patients with same diagnoses in 2020 compared to previous years. Prospective evaluation and further investigation into the reasons for these trends is needed.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Language:
English
Journal:
Brain Behav Immun Health
Year:
2021
Document Type:
Article
Affiliation country:
J.bbih.2021.100207
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