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Clinical characteristics of 14 COVID-19 deaths in Tianmen, China: a single-center retrospective study.
Hu, Jijia; Zhang, Yingang; Wang, Wei; Tao, Zhihe; Tian, Juan; Shao, Ning; Liu, Nian; Wei, Hui; Huang, Hao.
  • Hu J; Division of Nephrology, Renmin Hospital of Wuhan University, Hubei, China.
  • Zhang Y; Division of Medical Services, The First People's Hospital of Tianmen, Tianmen, Hubei, China.
  • Wang W; Division of Health Examination Center, The First People's Hospital of Tianmen, Tianmen, Hubei, China.
  • Tao Z; Director's Office, The First People's Hospital of Tianmen, Tianmen, Hubei, China.
  • Tian J; Division of Rheumatology, The First People's Hospital of Tianmen, Tianmen, Hubei, China.
  • Shao N; Division of Nephrology, The First People's Hospital of Tianmen, Tianmen, Hubei, China.
  • Liu N; Division of Rheumatology, The First People's Hospital of Tianmen, Tianmen, Hubei, China.
  • Wei H; Division of Cardiology, The First People's Hospital of Tianmen, Tianmen, Hubei, China. Xajh1998@126.com.
  • Huang H; Division of Rheumatology, The First People's Hospital of Tianmen, Tianmen, Hubei, China. ahuanghao@163.com.
BMC Infect Dis ; 21(1): 88, 2021 Jan 20.
Article in English | MEDLINE | ID: covidwho-1038476
ABSTRACT

BACKGROUND:

The treatment of critically ill patients with COVID-19 who were hospitalized in Wuhan has been reported. However, the clinical characteristics of patients who died of COVID-19 in regions with relatively scarce healthcare resources remain unknown.

METHODS:

In this retrospective study, a total of 14 patients who were admitted from January 18 to February 11, 2020 and died of COVID-19 were evaluated. The epidemiological, symptomatic, laboratory, radiological and treatment records were reviewed and analyzed.

RESULTS:

The mean age of the 14 patients was 56.7 (SD 15.3) years, and 8 (57.1%) were older than 50 years. Eight (57.1%) were men, and 11 (78.6%) had one or more high risk factors. The most common chronic diseases among these patients were cardiovascular disease (7, 50.0%), hypertension (6, 42.9%), and chronic kidney disease (5, 35.7%). General symptoms included cough (12, 85.7%), fever (11, 78.6%), and dyspnea (10, 71.4%). The median duration from the onset of symptoms to death was 11 (IQR 6.5-19.5) days, and the median duration from admission to death was 4.5 (1.0-11.8) days. Patients who died within 4.5 days had more severe pulmonary lesions, significantly reduced lymphocytes and elevated C-reactive protein (CRP). Most patients had organ dysfunction, including 13 (92.9%) with acute respiratory distress syndrome (ARDS), 4 (28.6%) with cardiac injury, 3 (21.4%) with acute kidney injury, and 3 (21.4%) with liver dysfunction.

CONCLUSIONS:

Elderly SARS-CoV-2-infected patients with comorbidities, especially those with ARDS and severe chest CT findings on admission, are at increased risk of death and deserve special attention and quality medical treatment.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: BMC Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: S12879-021-05770-z

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: BMC Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: S12879-021-05770-z