Your browser doesn't support javascript.
Demographic predictors of hospitalization and mortality in US children with COVID-19.
Moreira, Alvaro; Chorath, Kevin; Rajasekaran, Karthik; Burmeister, Fiona; Ahmed, Mubbasheer; Moreira, Axel.
  • Moreira A; Department of Pediatrics, University of Texas Health San Antonio, 7702 Floyd Curl Drive, San Antonio, TX, 78229, USA. MoreiraA@uthscsa.edu.
  • Chorath K; University of Pennsylvania, Philadelphia, PA, USA.
  • Rajasekaran K; University of Pennsylvania, Philadelphia, PA, USA.
  • Burmeister F; Department of Pediatrics, University of Texas Health San Antonio, 7702 Floyd Curl Drive, San Antonio, TX, 78229, USA.
  • Ahmed M; Baylor College of Medicine, Houston, TX, USA.
  • Moreira A; Baylor College of Medicine, Houston, TX, USA.
Eur J Pediatr ; 180(5): 1659-1663, 2021 May.
Article in English | MEDLINE | ID: covidwho-1039197
ABSTRACT
Understanding which children are at increased risk for poor outcome with COVID-19 is critical. In this study, we link pediatric population-based data from the US Center for Disease Control and Prevention to COVID-19 hospitalization and in-hospital death. In 27,045 US children with confirmed COVID-19, we demonstrate that African American [OR 2.28 (95% CI 1.93, 2.70)] or mixed race [OR 2.95 (95% CI 2.28, 3.82)] and an underlying medical condition [OR 3.55 (95% CI 3.14, 4.01)] are strong predictors for hospitalization. Death occurred in 39 (0.19%) of 20,096 hospitalized children; children with a prior medical condition had an increased odd for death [OR 8.8 (95% CI 3.7, 21.1)].

Conclusion:

Hospitalization and in-hospital death are rare in children diagnosed with COVID-19. However, children at higher risk for these outcomes include those with an underlying medical condition, as well as those of African American descent. What is Known • Demographic factors are independent prognosticators of poor outcome in children with COVID-19. What is New • Children with an underlying medical condition and those from an African American or mixed race/ethnicity are at high risk for COVID-19 hospitalization. • History of a comorbidity supersedes age, gender, and race/ethnicity as a risk factor for in-hospital pediatric COVID-19 death.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Hospital Mortality / COVID-19 Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn / Young adult Country/Region as subject: North America Language: English Journal: Eur J Pediatr Year: 2021 Document Type: Article Affiliation country: S00431-021-03955-x

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Hospital Mortality / COVID-19 Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn / Young adult Country/Region as subject: North America Language: English Journal: Eur J Pediatr Year: 2021 Document Type: Article Affiliation country: S00431-021-03955-x