Demographic predictors of hospitalization and mortality in US children with COVID-19.
Eur J Pediatr
; 180(5): 1659-1663, 2021 May.
Article
in English
| MEDLINE | ID: covidwho-1039197
ABSTRACT
Understanding which children are at increased risk for poor outcome with COVID-19 is critical. In this study, we link pediatric population-based data from the US Center for Disease Control and Prevention to COVID-19 hospitalization and in-hospital death. In 27,045 US children with confirmed COVID-19, we demonstrate that African American [OR 2.28 (95% CI 1.93, 2.70)] or mixed race [OR 2.95 (95% CI 2.28, 3.82)] and an underlying medical condition [OR 3.55 (95% CI 3.14, 4.01)] are strong predictors for hospitalization. Death occurred in 39 (0.19%) of 20,096 hospitalized children; children with a prior medical condition had an increased odd for death [OR 8.8 (95% CI 3.7, 21.1)].Conclusion:
Hospitalization and in-hospital death are rare in children diagnosed with COVID-19. However, children at higher risk for these outcomes include those with an underlying medical condition, as well as those of African American descent. What is Known ⢠Demographic factors are independent prognosticators of poor outcome in children with COVID-19. What is New ⢠Children with an underlying medical condition and those from an African American or mixed race/ethnicity are at high risk for COVID-19 hospitalization. ⢠History of a comorbidity supersedes age, gender, and race/ethnicity as a risk factor for in-hospital pediatric COVID-19 death.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Hospital Mortality
/
COVID-19
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
/
Young adult
Country/Region as subject:
North America
Language:
English
Journal:
Eur J Pediatr
Year:
2021
Document Type:
Article
Affiliation country:
S00431-021-03955-x
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