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Early clinical and CT features of COVID-19 and community-acquired pneumonia from a fever observation ward in Ningbo, China.
Qian, Guoqing; Lin, Yuanwei; Chen, Xueqin; Ma, Ada Hoi Yan; Zhang, Xuehui; Li, Guoxiang; Ruan, Xinzhong; Ruan, Liemin.
  • Qian G; Department of General Internal Medicine, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
  • Lin Y; Division of Respiratory Medicine, National Institute for Health Research, Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom.
  • Chen X; Department of Radiology, Ningbo Hospital of Zhejiang University, Ningbo, Zhejiang, China.
  • Ma AHY; Department of Chinese Traditional Medicine, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
  • Zhang X; Nottingham University Business School, University of Nottingham Ningbo, Ningbo, Zhejiang, China.
  • Li G; Department of General Internal Medicine, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
  • Ruan X; Department of General Internal Medicine, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
  • Ruan L; Department of Radiology, Ningbo Hospital of Zhejiang University, China.
Singapore Med J ; 63(4): 219-224, 2022 04.
Article in English | MEDLINE | ID: covidwho-1040168
ABSTRACT

INTRODUCTION:

We aimed to compare the early clinical manifestations, laboratory results and chest computed tomography (CT) images of COVID-19 patients with those of other community-acquired pneumonia (CAP) patients to differentiate CAP from COVID-19 before reverse transcription-polymerase chain reaction results are obtained.

METHODS:

The clinical and laboratory data and chest CT images of 51 patients were assessed in a fever observation ward for evidence of COVID-19 between January and February 2020.

RESULTS:

24 patients had laboratory-confirmed COVID-19, whereas 27 individuals had negative results. No statistical difference in clinical features was found between COVID-19 and CAP patients, except for diarrhoea. There was a significant difference in lymphocyte and eosinophil counts between COVID-19 and CAP patients. In total, 22 (91.67%) COVID-19 patients had bilateral involvement and multiple lesions according to their lung CT images; the left lower lobe (87.50%) and right lower lobe (95.83%) were affected most often, and all lesions were located in the peripheral zones of the lung. The most common CT feature of COVID-19 was ground-glass opacity, found in 95.83% of patients, compared to 66.67% of CAP patients.

CONCLUSION:

Diarrhoea, lymphocyte counts, eosinophil counts and CT findings (e.g. ground-glass opacity) could help to distinguish COVID-19 from CAP at an early stage of infection, based on findings from our fever observation ward.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Community-Acquired Infections / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Country/Region as subject: Asia Language: English Journal: Singapore Med J Year: 2022 Document Type: Article Affiliation country: Smedj.2021004

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Community-Acquired Infections / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Country/Region as subject: Asia Language: English Journal: Singapore Med J Year: 2022 Document Type: Article Affiliation country: Smedj.2021004