P253 Acute pulmonary emboli and COVID-19

ABSTRACT

P253 figure 1).COVID-19 associated PE’s were more likely to be unilateral (16/32 compared to 5/27 in COVID-19 negative group [p=0.025]) and trended towards more distal vessels (p=0.09). Accounting for age, an additional PE diagnosis did not significantly affect in-hospital COVID-19 mortality (OR 1.54 [CI 0.52–3.94], [p=0.38]).Abstract P253 Figure 1(a) Initial D-Dimer levels in COVID-19 patients without (L) and with (R) PE diagnosis on CTPA. (b) Proportion of CTPA’s diagnosing a PE at specified D-Dimer ranges[Figure omitted. See PDF]ConclusionOur results demonstrate increased detection of PE in COVID-19. Emboli are more likely to be unilateral, and more distally located. We postulate this may be due to higher rates of in-situ thrombosis rather than distant embolisation of clots. The radiological severity of COVID-19 lung disease does not appear to be strongly linked to PE detection rates which may suggest the hypercoagulable state in COVID-19 is independent from the inflammatory lung process. Patients with COVID-19 and co-existent PE’s have significantly higher D-Dimer’s, and further evaluation is needed into their use as a screening tool.