NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Biomol NMR Assign
; 15(1): 137-142, 2021 04.
Article
in English
| MEDLINE | ID: covidwho-1042942
ABSTRACT
SARS-CoV-2 is a novel pathogen causing pneumonia named COVID-19 and leading to a severe pandemic since the end of 2019. The genome of SARS-CoV-2 contains a macro domain that may play an important role in regulating ADP-ribosylation in host cells and initiating viral replication. Here, we report the 1H, 13C, and 15N resonance assignments of the SARS-CoV-2 macro domain. This work provides the ground for further structural deciphering and biophysical investigation in protein function and antiviral agent design.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Viral Proteins
/
Magnetic Resonance Spectroscopy
/
Viral Nonstructural Proteins
/
SARS-CoV-2
Language:
English
Journal:
Biomol NMR Assign
Journal subject:
Molecular Biology
/
Nuclear Medicine
Year:
2021
Document Type:
Article
Affiliation country:
S12104-020-09996-x
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