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[Air pollution and cardiovascular diseases]. / Luftverschmutzung und Herz-Kreislauf-Erkrankungen.
Münzel, Thomas; Hahad, Omar; Daiber, Andreas; Lelieveld, Jos.
  • Münzel T; Zentrum für Kardiologie - Kardiologie I, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland. tmuenzel@uni-mainz.de.
  • Hahad O; Zentrum für Kardiologie - Kardiologie I, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland.
  • Daiber A; Zentrum für Kardiologie - Kardiologie I, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland.
  • Lelieveld J; Max-Planck-Institut für Chemie, Johannes-Gutenberg-Universität Mainz, Mainz, Deutschland.
Herz ; 46(2): 120-128, 2021 Mar.
Article in German | MEDLINE | ID: covidwho-1043352
Semantic information from SemMedBD (by NLM)
1. Structure of wall of blood vessel LOCATION_OF Reactive Oxygen Species
Subject
Structure of wall of blood vessel
Predicate
LOCATION_OF
Object
Reactive Oxygen Species
2. Cardiovascular Risk COEXISTS_WITH Cerebrovascular accident
Subject
Cardiovascular Risk
Predicate
COEXISTS_WITH
Object
Cerebrovascular accident
3. Cardiovascular Risk COEXISTS_WITH Chronic myocardial ischemia
Subject
Cardiovascular Risk
Predicate
COEXISTS_WITH
Object
Chronic myocardial ischemia
4. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
5. Structure of wall of blood vessel LOCATION_OF Reactive Oxygen Species
Subject
Structure of wall of blood vessel
Predicate
LOCATION_OF
Object
Reactive Oxygen Species
6. Cardiovascular Risk COEXISTS_WITH Cerebrovascular accident
Subject
Cardiovascular Risk
Predicate
COEXISTS_WITH
Object
Cerebrovascular accident
7. Cardiovascular Risk COEXISTS_WITH Chronic myocardial ischemia
Subject
Cardiovascular Risk
Predicate
COEXISTS_WITH
Object
Chronic myocardial ischemia
8. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
Air pollution in the environment and in households is responsible worldwide for almost 9 million preventable premature deaths per year and almost 800,000 such deaths within Europe. Air pollution therefore shortens life expectancy worldwide by almost 3 years. Smoking, a proven cardiovascular risk factor, shortens the mean life expectancy by 2.2 years. Epidemiological studies have shown that air pollution from fine and coarse particulate matter is associated with increased cardiovascular morbidity and mortality. Responsible for this are mainly cardiovascular diseases, such as coronary heart disease, heart attack, heart failure, stroke, hypertension and also diabetes, which are mainly caused or aggravated by fine particulate matter. After inhalation fine particulate matter can reach the brain directly and also reach the bloodstream via a transition process. There, the particles are absorbed by the blood vessels where they stimulate the formation of reactive oxygen species (ROS) in the vascular wall. They therefore promote the formation of atherosclerotic changes and in this way increase the cardiovascular risks, especially an increase in chronic ischemic heart disease and stroke. Recent studies also reported that in coronavirus disease 2019 (COVID-19) patients a high degree of air pollution is correlated with severe disease courses with cardiovascular complications and pulmonary diseases. This necessitates preventive measures, such as lowering of the upper limits for air pollutants. Individual measures to mitigate the health consequences of fine particulate matter are also discussed.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Air Pollution / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: German Journal: Herz Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Air Pollution / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: German Journal: Herz Year: 2021 Document Type: Article