Replicative capacity of four porcine enteric coronaviruses in LLC-PK1 cells.
Arch Virol
; 166(3): 935-941, 2021 Mar.
Article
in English
| MEDLINE | ID: covidwho-1045234
ABSTRACT
Enteric coronaviruses (CoVs) are major pathogens that cause diarrhea in piglets. To date, four porcine enteric CoVs have been identified transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and HKU2-like porcine enteric alphacoronavirus (PEAV). In this study, we investigated the replicative capacity of these four enteric CoVs in LLC-PK1 cells, a porcine kidney cell line. The results showed that LLC-PK1 cells are susceptible to all four enteric CoVs, particularly to TGEV and PDCoV infections, indicating that LLC-PK1 cells can be applied to porcine enteric CoV research in vitro, particularly for coinfection studies.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Virus Replication
/
Transmissible gastroenteritis virus
/
Porcine epidemic diarrhea virus
/
Gastroenteritis, Transmissible, of Swine
/
Deltacoronavirus
Limits:
Animals
Language:
English
Journal:
Arch Virol
Year:
2021
Document Type:
Article
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