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Replicative capacity of four porcine enteric coronaviruses in LLC-PK1 cells.
Xiao, Wenwen; Wang, Xunlei; Wang, Jing; Fang, Puxian; Xiao, Shaobo; Fang, Liurong.
  • Xiao W; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.
  • Wang X; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, 430070, People's Republic of China.
  • Wang J; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.
  • Fang P; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, 430070, People's Republic of China.
  • Xiao S; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.
  • Fang L; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, 430070, People's Republic of China.
Arch Virol ; 166(3): 935-941, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1045234
ABSTRACT
Enteric coronaviruses (CoVs) are major pathogens that cause diarrhea in piglets. To date, four porcine enteric CoVs have been identified transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and HKU2-like porcine enteric alphacoronavirus (PEAV). In this study, we investigated the replicative capacity of these four enteric CoVs in LLC-PK1 cells, a porcine kidney cell line. The results showed that LLC-PK1 cells are susceptible to all four enteric CoVs, particularly to TGEV and PDCoV infections, indicating that LLC-PK1 cells can be applied to porcine enteric CoV research in vitro, particularly for coinfection studies.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Replication / Transmissible gastroenteritis virus / Porcine epidemic diarrhea virus / Gastroenteritis, Transmissible, of Swine / Deltacoronavirus Limits: Animals Language: English Journal: Arch Virol Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Replication / Transmissible gastroenteritis virus / Porcine epidemic diarrhea virus / Gastroenteritis, Transmissible, of Swine / Deltacoronavirus Limits: Animals Language: English Journal: Arch Virol Year: 2021 Document Type: Article