&#945;1-Antitrypsin deficiency and the risk of COVID-19: an urgent call to action.

Yang, Chengliang; Chapman, Kenneth R; Wong, Aaron; Liu, Mingyao

α1-Antitrypsin deficiency and the risk of COVID-19: an urgent call to action.

Yang, Chengliang; Chapman, Kenneth R; Wong, Aaron; Liu, Mingyao.

Yang C; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada.
Chapman KR; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada; Division of Respiratory Medicine, Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada.
Wong A; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L
Liu M; Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada; Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L

Lancet Respir Med ; 9(4): 337-339, 2021 04.

Article in English | MEDLINE | ID: covidwho-1492859

Subject(s)

COVID-19/epidemiology; alpha 1-Antitrypsin Deficiency/epidemiology; alpha 1-Antitrypsin/genetics; COVID-19/diagnosis; COVID-19/genetics; Clinical Trials as Topic; Comorbidity; Genetic Predisposition to Disease; Humans; Mutation; Risk Factors; SARS-CoV-2/metabolism; Serine Endopeptidases/metabolism; Serine Proteinase Inhibitors/pharmacology; Serine Proteinase Inhibitors/therapeutic use; Severity of Illness Index; Virus Internalization/drug effects; alpha 1-Antitrypsin/metabolism; alpha 1-Antitrypsin/pharmacology; alpha 1-Antitrypsin/therapeutic use; alpha 1-Antitrypsin Deficiency/genetics; COVID-19 Drug Treatment

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Alpha 1-Antitrypsin / Alpha 1-Antitrypsin Deficiency / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Lancet Respir Med Year: 2021 Document Type: Article Affiliation country: S2213-2600(21)00018-7

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