Intrauterine Transmission of SARS-CoV-2.

Stonoga, Emanuele T S; de Almeida Lanzoni, Laura; Rebutini, Patricia Zadorosnei; Permegiani de Oliveira, André Luiz; Chiste, Jullie Anne; Fugaça, Cyllian Arias; Prá, Daniele M M; Percicote, Ana Paula; Rossoni, Andrea; Nogueira, Meri Bordignon; de Noronha, Lucia; Raboni, Sonia Mara

Stonoga, Emanuele T S; de Almeida Lanzoni, Laura; Rebutini, Patricia Zadorosnei; Permegiani de Oliveira, André Luiz; Chiste, Jullie Anne; Fugaça, Cyllian Arias; Prá, Daniele M M; Percicote, Ana Paula; Rossoni, Andrea; Nogueira, Meri Bordignon; de Noronha, Lucia; Raboni, Sonia Mara.

Emerg Infect Dis ; 27(2): 638-641, 2021 Feb.

Article in English | MEDLINE | ID: covidwho-1048932

ABSTRACT

ABSTRACT

We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic infiltrate in muscle in the placenta and fetal tissue. Placenta and umbilical cord blood tested positive for the virus by PCR, confirming transplacental transmission.

Subject(s)

COVID-19/transmission; Infectious Disease Transmission, Vertical; Pregnancy Complications, Infectious/virology; SARS-CoV-2; Adult; COVID-19/virology; Female; Fetal Death/etiology; Fetus/virology; Humans; Placenta/virology; Pregnancy

Keywords

2019 novel coronavirus disease; Brazil; COVID-19; RT-PCR; SARS-CoV-2; autopsy; congenital transmission; coronavirus; coronavirus disease; diagnosis; intrauterine transmission; placenta; pregnancy; respiratory infections; saliva; severe acute respiratory syndrome coronavirus 2; stillbirth; swabs; testing; upper respiratory swab samples; viruses; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / Infectious Disease Transmission, Vertical / SARS-CoV-2 / COVID-19 Type of study: Case report Limits: Adult / Female / Humans / Pregnancy Language: English Journal: Emerg Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article

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