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The Potential Use of Hypochlorous Acid and a Smart Prefabricated Sanitising Chamber to Reduce Occupation-Related COVID-19 Exposure.
Nguyen, Kate; Bui, Dinh; Hashemi, Mahak; Hocking, Dianna M; Mendis, Priyan; Strugnell, Richard A; Dharmage, Shyamali C.
  • Nguyen K; School of Engineering, RMIT University, Melbourne, Victoria, Australia.
  • Bui D; Centre of Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Victoria, Australia.
  • Hashemi M; School of Engineering, RMIT University, Melbourne, Victoria, Australia.
  • Hocking DM; ARC Training Centre on Advanced Manufacturing of Prefabricated Housing, The University of Melbourne, Melbourne, Victoria, Australia.
  • Mendis P; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
  • Strugnell RA; ARC Training Centre on Advanced Manufacturing of Prefabricated Housing, The University of Melbourne, Melbourne, Victoria, Australia.
  • Dharmage SC; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Risk Manag Healthc Policy ; 14: 247-252, 2021.
Article in English | MEDLINE | ID: covidwho-1052463
Semantic information from SemMedBD (by NLM)
1. hypochlorous acid DISRUPTS Occupational Exposure
Subject
hypochlorous acid
Predicate
DISRUPTS
Object
Occupational Exposure
2. hypochlorous acid DISRUPTS Occupational Exposure
Subject
hypochlorous acid
Predicate
DISRUPTS
Object
Occupational Exposure
ABSTRACT
This work is part of a project on the development of a smart prefabricated sanitising chamber (SPSC) to provide extra measures against the transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Stabilised hypochlorous acid (HOCl) is an approved disinfectant against SARS-CoV-2 by the Environmental Protection Association US in its liquid form on non-porous surfaces. This review is extended to cover its viricidal/bactericidal efficacy in aerosolised or sprayed form which showed an effective dose of as low as 20 ppm and the exposure duration of at least 60 s. The aerosolised application was also recommended with particle size of less than 200 µm to increase the contact with pathogens. The review also includes the safety and toxicity of HOCl with different concentrations. The review calls for more investigations into the effect of HOCl in mist and fog form on the respiratory system when transitioning through the proposed SPSC.

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Type of study: Determinantes_sociais_saude Language: English Journal: Risk Manag Healthc Policy Clinical aspect: Etiology Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Type of study: Determinantes_sociais_saude Language: English Journal: Risk Manag Healthc Policy Clinical aspect: Etiology Year: 2021
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